Cth ELISA Kit for Mouse(Mus musculus) | EIAab.comCth ELISA Kit for Mouse(Mus musculus)

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Cth (Gene name),

Cystathionine gamma-lyase (Protein name ), CGL_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cth;

Protein name:

Cystathionine gamma-lyase;

Alternative:

Gamma-cystathionase;Gamma-cystathionase;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotetramer (By similarity). Interacts with CALM in a calcium-dependent manner.

Function:

Catalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

398

Sequence:

50:

100:

150:

200:

250:

300:

350:

398:

AIMTHASVPE | KDRATLGIND | TLIRLSVGLE | DEQDLLEDLD | RALKAAHP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:107869

SMR:

Q8VCN5

UniGene:

Mm.28301

String:

Q8VCN5

Pfam:

PF01053

Uniprot:

Q8VCN5

FOR

ELISA Kit for Mouse Cystathionine gamma-lyase

Cat.:

E1538h

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Packing:

96T

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ELISA Kit for Mouse Cystathionine gamma-lyase

Cat.:

E1538r

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Packing:

96T

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ELISA Kit for Mouse Cystathionine gamma-lyase

Cat.:

E1538m

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Cystathionine gamma-lyase

Cat.:

E1538p

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Cystathionine gamma-lyase

Cat.:

E1538b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Cystathionine gamma-lyase

Cat.:

U1538r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Cystathionine gamma-lyase

Cat.:

U1538p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Cystathionine gamma-lyase

Cat.:

U1538h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse Cystathionine gamma-lyase

Cat.:

U1538m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Cystathionine gamma-lyase

Cat.:

U1538b

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Cystathionine gamma-lyase

Cat.:

P1538Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Cystathionine gamma-lyase

Cat.:

P1538Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Cystathionine gamma-lyase

Cat.:

P1538Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Cystathionine gamma-lyase

Protein for Mouse Cystathionine gamma-lyase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression."
Ishii I. , Akahoshi N. , Yu X.-N. , Kobayashi Y. , Namekata K. , Komaki G. , Kimura H.
Biochem. J.381:113-123(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];TISSUE SPECIFICITY
strain: 129/SvJ.
strain: C57BL/6J.
tissue: Kidney.
tissue: Spleen.
2.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Kidney.
4.

"H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase."
Yang G. , Wu L. , Jiang B. , Yang W. , Qi J. , Cao K. , Meng Q. , Mustafa A.K. , Mu W. , Zhang S. , Snyder S.H. , Wang R.
Science322:587-590(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION;INTERACTION WITH CALM;ENZYME REGULATION
5.

"H2S signals through protein S-sulfhydration."
Mustafa A.K. , Gadalla M.M. , Sen N. , Kim S. , Mu W. , Gazi S.K. , Barrow R.K. , Yang G. , Wang R. , Snyder S.H.
Sci. Signal.2:RA72-RA72(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS CYSTEINE-PROTEIN SULFHYDRASE;DISRUPTION PHENOTYPE
6.

"Hydrogen sulfide-linked sulfhydration of NF-kappaB mediates its antiapoptotic actions."
Sen N. , Paul B.D. , Gadalla M.M. , Mustafa A.K. , Sen T. , Xu R. , Kim S. , Snyder S.H.
Mol. Cell45:13-24(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS CYSTEINE-PROTEIN SULFHYDRASE

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