Protein name:
Chromodomain-helicase-DNA-binding protein 1 (CHD-1) ;
Alternative:
ATP-dependent helicase CHD1 ;
Organism:
Chicken (Gallus gallus).
General Annotation
Sub Unit:
Component of the SAGA complex (By similarity). Interacts with SSRP1.
Function:
ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin remodeling, but also required to maintain a specific chromatin configuration across the genome. Required for maintaining open chromatin and pluripotency in embryonic stem cells (By similarity). Required for centromeric localization of CENPA.
Subcellular Location:
Nucleus
Chromosome
centromere
Protein Attributes:
50:
MNGHSDEESV | RNSSGESRSD | DDSGSASGSG | SGSSSGSSSD | GSSSQSGSSD |
100:
SESGSESGSQ | SESESDTSRE | KKQVQAKPPK | ADGSEFWKSS | PSILAVQRSA |
150:
VLKKQQQQQK | AASSDSGSEE | DSSSSEDSAD | DSSSETKKKK | HKDEDWQMSG |
200:
SGSVSGTGSD | SESEEDGDKS | SCEESESDYE | PKNKVKSRKP | PSRIKPKSGK |
250:
KSTGQKKRQL | DSSEEEEDDD | EDYDKRGSRR | QATVNVSYKE | AEETKTDSDD |
300:
LLEVCGEDVP | QTEEDEFETI | EKFMDSRIGR | KGATGASTTI | YAVEVDGDPN |
350:
AGFEKSKELG | EIQYLIKWKG | WSHIHNTWET | EETLKQQNVK | GMKKLDNYKK |
400:
KDQETKRWLK | NASPEDVEYY | NCQQELTDDL | HKQYQIVERI | IAHSNQKSAA |
450:
GYPDYYCKWQ | GLPYSECSWE | DGALIAKKFQ | ARIDEYFSRN | QSKTTPFKDC |
500:
KVLKQRPRFV | ALKKQPSYIG | GHESLELRDY | QLNGLNWLAH | SWCKGNSCIL |
550:
ADEMGLGKTI | QTISFLNYLF | HEHQLYGPFL | LVVPLSTLTS | WQREIQTWAP |
600:
QMNAVVYLGD | ITSRNMIRTH | EWMHPQTKRL | KFNILLTTYE | ILLKDKSFLG |
650:
GLNWAFIGVD | EAHRLKNDDS | LLYKTLIDFK | SNHRLLITGT | PLQNSLKELW |
700:
SLLHFIMPEK | FSSWEDFEEE | HGKGREYGYA | SLHKELEPFL | LRRVKKDVEK |
750:
SLPAKVEQIL | RMEMSALQKQ | YYKWILTRNY | KALSKGSKGS | TSGFLNIMME |
800:
LKKCCNHCYL | IKPPDDNEFY | NKQEALQHLI | RSSGKLILLD | KLLIRLRERG |
850:
NRVLIFSQMV | RMLDILAEYL | KYRQFPFQRL | DGSIKGELRK | QALDHFNAEG |
900:
SEDFCFLLST | RAGGLGINLA | SADTVVIFDS | DWNPQNDLQA | QARAHRIGQK |
950:
KQVNIYRLVT | KGSVEEDILE | RAKKKMVLDH | LVIQRMDTTG | KTVLHTGSTP |
1000:
SSSTPFNKEE | LSAILKFGAE | ELFKEPEGEE | QEPQEMDIDE | ILKRAETREN |
1050:
EPGPLTVGDE | LLSQFKVANF | SNMDEDDIEL | EPERNSRNWE | EIIPESQRRR |
1100:
IEEEERQKEL | EEIYMLPRMR | NCAKQISFNG | SEGRRSRSRR | YSGSDSDSIT |
1150:
ERKRPKKRGR | PRTIPRENIK | GFSDAEIRRF | IKSYKKFGGP | LERLDAVARD |
1200:
AELVDKSETD | LRRLGELVHN | GCIKALKDNS | SGQERAGGRL | GKVKGPTFRI |
1250:
SGVQVNAKLV | ISHEEELAPL | HKSIPSDPEE | RKRYVIPCHT | KAAHFDIDWG |
1300:
KEDDSNLLVG | IYEYGYGSWE | MIKMDPDLSL | TQKILPDDPD | KKPQAKQLQT |
1350:
RADYLIKLLN | KDLARKEAQR | LAGAGNSKRR | KTRNKKNKMK | ASKIKEEIKS |
1400:
DSSPQPSEKS | DEDDDEEDNK | VNEIKSENKE | KSKKIPLLDT | PVHITATSEP |
1450:
VPISEESEEL | DQKTFSVCKE | RMRPVKAALK | QLDRPEKGLS | EREQLEHTRQ |
1500:
CLIKIGDHIT | ECLKEYTNPE | QIKQWRKNLW | IFVSKFTEFD | ARKLHKLYKH |
1550:
AIKKRQESQQ | HNDQNISSNV | NTHVIRNPDV | ERLKETTNHD | DSSRDSYSSD |
1600:
RHLSQYHDHH | KDRHQGDAYK | KSDSRKRPYS | AFSNGKDHRD | WDHYKQDSRY |
1650:
YSDSKHRKLD | DHRSRDHRSN | LEGNLKDSRG | HSDHRSHSDH | RIHSDHRSTS |
1700:
EYSHHKSSRD | YRYHSDWQMD | HRASGSGPRS | PLDQRSPYGS | RSPLGHRSPF |
1719:
EHSSDHKSTP | EHTWSSRKT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Human
Mouse
ELISA Kit for Chicken CHD-1
ELISA Kit for Chicken CHD-1
ELISA Kit for Chicken CHD-1
CLIA Kit for Chicken CHD-1
CLIA Kit for Chicken CHD-1
CLIA Kit for Chicken CHD-1
Polyclonal Antibody for Chicken CHD-1
Polyclonal Antibody for Chicken CHD-1
Polyclonal Antibody for Chicken CHD-1
Monoclonal Antibody for Chicken CHD-1
Monoclonal Antibody for Chicken CHD-1
Monoclonal Antibody for Chicken CHD-1
Protein for Chicken CHD-1
Protein for Chicken CHD-1
Protein for Chicken CHD-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH SSRP1