CHKA ELISA Kit for Human(Homo sapiens) | EIAab.comCHKA ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > CHKA(Gene name) > Human

CHKA (Gene name),

Choline kinase alpha (Protein name ), CHKA_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

CHKA(CHK;CKI);

Protein name:

Choline kinase alpha(CK);

Alternative:

2.7.1.82;Ethanolamine kinase;(EK);CHETK-alpha;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer with CHKB (By similarity). Homodimer.

Function:

Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

457

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

457:

QKRKLGV

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

P35790

KEGG:

hsa:1119

Pfam:

PF01633

SMR:

P35790

MIM:

118491

STRING:

9606.ENSP00000265689

UniGene:

Hs.77221

Uniprot:

P35790

FOR

ELISA Kit for Human CK

Cat.:

E1985m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human CK

Cat.:

E1985r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human CK

Cat.:

E1985h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human CK

Cat.:

U1985h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human CK

Cat.:

U1985m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human CK

Cat.:

U1985r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human CK

Cat.:

P1985Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human CK

Cat.:

P1985Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human CK

Cat.:

P1985Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human CK

Protein for Human CK

Cat.:

R1985h

Price:

Please sign in first.

Packing:

1mg

Purity:

>90%

Protein for Human CK

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning of a human choline kinase cDNA by complementation of the yeast cki mutation."
Hosaka K. , Tanaka S. , Nikawa J. , Yamashita S.
FEBS Lett.304:229-232(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANTS GLY-220 AND GLN-422
tissue: Testis.
4.

"Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment."
Gallego-Ortega D. , Ramirez de Molina A. , Ramos M.A. , Valdes-Mora F. , Barderas M.G. , Sarmentero-Estrada J. , Lacal J.C.
PLoS ONE4:E7819-E7819(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES
5.

"Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine."
Malito E. , Sekulic N. , Too W.C. , Konrad M. , Lavie A.
J. Mol. Biol.364:136-151(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) OF 50-439 IN COMPLEX WITH ADP AND PHOSPHOCHOLINE;SUBUNIT;BIOPHYSICOCHEMICAL PROPERTIES
6.

"Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity."
Hong B.S. , Allali-Hassani A. , Tempel W. , Finerty P.J. Jr. , Mackenzie F. , Dimov S. , Vedadi M. , Park H.W.
J. Biol. Chem.285:16330-16340(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 75-457 IN COMPLEX WITH HEMICHOLINIUM-3 AND ADP

Product Feedback Wall

* Email:
*Comments: