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Index > Protein center > Bche(Gene name) > Mouse
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  • Bche (Gene name),
  • Cholinesterase (Protein name ),  CHLE_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Bche;
    Protein name:
    Cholinesterase;
    Alternative:
    Butyrylcholine esterase;Acylcholine acylhydrolase;Pseudocholinesterase;Choline esterase II;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homotetramer; disulfide-linked. Dimer of dimers.
    Function:
    Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    603
    Sequence:
    50:
    MQTQHTKVTQ | THFLLWILLL | CMPFGKSHTE | EDFIITTKTG | RVRGLSMPVL | 
    100:
    GGTVTAFLGI | PYAQPPLGSL | RFKKPQPLNK | WPDIHNATQY | ANSCYQNIDQ | 
    150:
    AFPGFQGSEM | WNPNTNLSED | CLYLNVWIPV | PKPKNATVMV | WIYGGGFQTG | 
    200:
    TSSLPVYDGK | FLARVERVIV | VSMNYRVGAL | GFLAFPGNPD | APGNMGLFDQ | 
    250:
    QLALQWVQRN | IAAFGGNPKS | ITIFGESAGA | ASVSLHLLCP | QSYPLFTRAI | 
    300:
    LESGSSNAPW | AVKHPEEARN | RTLTLAKFTG | CSKENEMEMI | KCLRSKDPQE | 
    350:
    ILRNERFVLP | SDSILSINFG | PTVDGDFLTD | MPHTLLQLGK | VKKAQILVGV | 
    400:
    NKDEGTAFLV | YGAPGFSKDN | DSLITRKEFQ | EGLNMYFPGV | SRLGKEAVLF | 
    450:
    YYVDWLGEQS | PEVYRDALDD | VIGDYNIICP | ALEFTKKFAE | LENNAFFYFF | 
    500:
    EHRSSKLPWP | EWMGVMHGYE | IEFVFGLPLG | RRVNYTRAEE | IFSRSIMKTW | 
    550:
    ANFAKYGHPN | GTQGNSTMWP | VFTSTEQKYL | TLNTEKSKIY | SKLRAPQCQF | 
    600:
    WRLFFPKVLE | MTGDIDETEQ | EWKAGFHRWS | NYMMDWQNQF | NDYTSKKESC | 
    603:
    TAL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cholinesterase
    Cat.:
    E8904h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Cholinesterase
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse Cholinesterase
    Cat.:
    E8904m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Cholinesterase
    Cat.:
    E8904b
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    ELISA Kit for Mouse Cholinesterase
    Cat.:
    E8904p
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Cholinesterase
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Cholinesterase
    Cat.:
    U8904m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cholinesterase
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Cholinesterase
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Cholinesterase
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Cholinesterase
    Cat.:
    U8904h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Cholinesterase
    Cat.:
    U8904b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Cholinesterase
    Polyclonal Antibody for Mouse Cholinesterase
    Cat.:
    P8904Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cholinesterase
    Polyclonal Antibody for Mouse Cholinesterase
    Polyclonal Antibody for Mouse Cholinesterase
    Polyclonal Antibody for Mouse Cholinesterase
    Cat.:
    P8904Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Cholinesterase
    Monoclonal Antibody for Mouse Cholinesterase
    Monoclonal Antibody for Mouse Cholinesterase
    Monoclonal Antibody for Mouse Cholinesterase
    Monoclonal Antibody for Mouse Cholinesterase
    Monoclonal Antibody for Mouse Cholinesterase
    Protein for Mouse Cholinesterase
    Protein for Mouse Cholinesterase
    Protein for Mouse Cholinesterase
    Protein for Mouse Cholinesterase
    Protein for Mouse Cholinesterase
    Protein for Mouse Cholinesterase

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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning of mouse acetylcholinesterase: tissue distribution of alternatively spliced mRNA species."
      Rachinsky T.L. , Camp S. , Li Y. , Ekstroem T.J. , Newton M. , Taylor P.
      Neuron5:317-327(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Liver.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "Use of the polymerase chain reaction for homology probing of butyrylcholinesterase from several vertebrates."
      Arpagaus M. , Chatonnet A. , Masson P. , Newton M. , Vaughan T.A. , Bartels C.F. , Nogueira C.P. , la Du B.N. , Lockridge O.
      J. Biol. Chem.266:6966-6974(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 97-237
      tissue: Liver.
    5. 5.
      "Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity."
      Hartmann J. , Kiewert C. , Duysen E.G. , Lockridge O. , Greig N.H. , Klein J.
      J. Neurochem.100:1421-1429(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    6. 6.
      "Butyrylcholinesterase and the control of synaptic responses in acetylcholinesterase knockout mice."
      Girard E. , Bernard V. , Minic J. , Chatonnet A. , Krejci E. , Molgo J.
      Life Sci.80:2380-2385(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission."
      Duysen E.G. , Li B. , Darvesh S. , Lockridge O.
      Toxicology233:60-69(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
    8. 8.
      "The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency."
      Li B. , Duysen E.G. , Carlson M. , Lockridge O.
      J. Pharmacol. Exp. Ther.324:1146-1154(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
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