Gene name:
CHSY3 (CHSY2;CSS3) ;
Protein name:
Chondroitin sulfate synthase 3 ;
Alternative:
Chondroitin glucuronyltransferase 3 ;Carbohydrate synthase 2 ;Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II ;Chondroitin synthase 2 (ChSy-2) ;N-acetylgalactosaminyltransferase 3 ;N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.
Subcellular Location:
Golgi apparatus
Golgi stack membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MAVRSRRPWM | SVALGLVLGF | TAASWLIAPR | VAELSERKRR | GSSLCSYYGR |
100:
SAAGPRAGAQ | QPLPQPQSRP | RQEQSPPPAR | QDLQGPPLPE | AAPGITSFRS |
150:
SPWQQPPPLQ | QRRRGREPEG | ATGLPGAPAA | EGEPEEEDGG | AAGQRRDGRP |
200:
GSSHNGSGDG | GAAAPSARPR | DFLYVGVMTA | QKYLGSRALA | AQRTWARFIP |
250:
GRVEFFSSQQ | PPNAGQPPPP | LPVIALPGVD | DSYPPQKKSF | MMIKYMHDHY |
300:
LDKYEWFMRA | DDDVYIKGDK | LEEFLRSLNS | SKPLYLGQTG | LGNIEELGKL |
350:
GLEPGENFCM | GGPGMIFSRE | VLRRMVPHIG | ECLREMYTTH | EDVEVGRCVR |
400:
RFGGTQCVWS | YEMQQLFHEN | YEHNRKGYIQ | DLHNSKIHAA | ITLHPNKRPA |
450:
YQYRLHNYML | SRKISELRYR | TIQLHRESAL | MSKLSNTEVS | KEDQQLGVIP |
500:
SFNHFQPRER | NEVIEWEFLT | GKLLYSAAEN | QPPRQSLSSI | LRTALDDTVL |
550:
QVMEMINENA | KSRGRLIDFK | EIQYGYRRVN | PMHGVEYILD | LLLLYKRHKG |
600:
RKLTVPVRRH | AYLQQLFSKP | FFRETEELDV | NSLVESINSE | TQSFSFISNS |
650:
LKILSSFQGA | KEMGGHNEKK | VHILVPLIGR | YDIFLRFMEN | FENMCLIPKQ |
700:
NVKLVIILFS | RDSGQDSSKH | IELIKGYQNK | YPKAEMTLIP | MKGEFSRGLG |
750:
LEMASAQFDN | DTLLLFCDVD | LIFREDFLQR | CRDNTIQGQQ | VYYPIIFSQY |
800:
DPKVTNGGNP | PTDDYFIFSK | KTGFWRDYGY | GITCIYKSDL | LGAGGFDTSI |
850:
QGWGLEDVDL | YNKVILSGLR | PFRSQEVGVV | HIFHPVHCDP | NLDPKQYKMC |
882:
LGSKASTFAS | TMQLAELWLE | KHLGVRYNRT | LS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Chondroitin sulfate synthase 3
ELISA Kit for Human Chondroitin sulfate synthase 3
CLIA Kit for Human Chondroitin sulfate synthase 3
CLIA Kit for Human Chondroitin sulfate synthase 3
Polyclonal Antibody for Human Chondroitin sulfate synthase 3
Polyclonal Antibody for Human Chondroitin sulfate synthase 3
Monoclonal Antibody for Human Chondroitin sulfate synthase 3
Monoclonal Antibody for Human Chondroitin sulfate synthase 3
Protein for Human Chondroitin sulfate synthase 3
Protein for Human Chondroitin sulfate synthase 3
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Chondroitin sulfate synthase-3. Molecular cloning and characterization."
Yada T.
,
Sato T.
,
Kaseyama H.
,
Gotoh M.
,
Iwasaki H.
,
Kikuchi N.
,
Kwon Y.-D.
,
Togayachi A.
,
Kudo T.
,
Watanabe H.
,
Narimatsu H.
,
Kimata K.
J. Biol. Chem.278:39711-39725(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;COFACTOR;TISSUE SPECIFICITY
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Pancreas .
tissue :
Placenta .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]