Protein name:
Carbohydrate sulfotransferase 3 ;
Alternative:
Chondroitin 6-sulfotransferase ;Chondroitin 6-O-sulfotransferase 1 (C6ST-1) ;Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0 (GST-0) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen.
Subcellular Location:
Golgi apparatus membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MEKGLTLPQD | CRDFVHSLKM | RSKYALFLVF | VVIVFVFIEK | ENKIISRVSD |
100:
KLKQIPQALA | DANSTDPALI | LAENASLLSL | SELDSAFSQL | QSRLRNLSLQ |
150:
LGVEPAMEAA | GEEEEEQRKE | EEPPRPAVAG | PRRHVLLMAT | TRTGSSFVGE |
200:
FFNQQGNIFY | LFEPLWHIER | TVSFEPGGAN | AAGSALVYRD | VLKQLFLCDL |
250:
YVLEHFITPL | PEDHLTQFMF | RRGSSRSLCE | DPVCTPFVKK | VFEKYHCKNR |
300:
RCGPLNVTLA | AEACRRKEHM | ALKAVRIRQL | EFLQPLAEDP | RLDLRVIQLV |
350:
RDPRAVLASR | MVAFAGKYKT | WKKWLDDEGQ | DGLREEEVQR | LRGNCESIRL |
400:
SAELGLRQPA | WLRGRYMLVR | YEDVARGPLQ | KAREMYRFAG | IPLTPQVEDW |
450:
IQKNTQAAHD | GSGIYSTQKN | SSEQFEKWRF | SMPFKLAQVV | QAACGPAMRL |
479:
FGYKLARDAA | ALTNRSVSLL | EERGTFWVT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Mouse
Human
Rat
ELISA Kit for Human Carbohydrate sulfotransferase 3
ELISA Kit for Human Carbohydrate sulfotransferase 3
ELISA Kit for Human Carbohydrate sulfotransferase 3
ELISA Kit for Human Carbohydrate sulfotransferase 3
CLIA Kit for Human Carbohydrate sulfotransferase 3
CLIA Kit for Human Carbohydrate sulfotransferase 3
CLIA Kit for Human Carbohydrate sulfotransferase 3
CLIA Kit for Human Carbohydrate sulfotransferase 3
Polyclonal Antibody for Human Carbohydrate sulfotransferase 3
Polyclonal Antibody for Human Carbohydrate sulfotransferase 3
Polyclonal Antibody for Human Carbohydrate sulfotransferase 3
Polyclonal Antibody for Human Carbohydrate sulfotransferase 3
Monoclonal Antibody for Human Carbohydrate sulfotransferase 3
Monoclonal Antibody for Human Carbohydrate sulfotransferase 3
Monoclonal Antibody for Human Carbohydrate sulfotransferase 3
Monoclonal Antibody for Human Carbohydrate sulfotransferase 3
Protein for Human Carbohydrate sulfotransferase 3
Protein for Human Carbohydrate sulfotransferase 3
Protein for Human Carbohydrate sulfotransferase 3
Protein for Human Carbohydrate sulfotransferase 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
tissue :
Fetal brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
tissue :
Placenta .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLN-357
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT SEDC-JD GLN-304
5.
"Congenital joint dislocations caused by carbohydrate sulfotransferase 3 deficiency in recessive Larsen syndrome and humero-spinal dysostosis."
Hermanns P.
,
Unger S.
,
Rossi A.
,
Perez-Aytes A.
,
Cortina H.
,
Bonafe L.
,
Boccone L.
,
Setzu V.
,
Dutoit M.
,
Sangiorgi L.
,
Pecora F.
,
Reicherter K.
,
Nishimura G.
,
Spranger J.
,
Zabel B.
,
Superti-Furga A.
Am. J. Hum. Genet.82:1368-1374(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS SEDC-JD TRP-222; PRO-259; PRO-307 AND LYS-372;VARIANT GLN-357;CHARACTERIZATION OF VARIANTS SEDC-JD TRP-222 AND PRO-259
6.
Hermanns P.
,
Unger S.
,
Rossi A.
,
Perez-Aytes A.
,
Cortina H.
,
Bonafe L.
,
Boccone L.
,
Setzu V.
,
Dutoit M.
,
Sangiorgi L.
,
Pecora F.
,
Reicherter K.
,
Nishimura G.
,
Spranger J.
,
Zabel B.
,
Superti-Furga A.
Am. J. Hum. Genet.83:293-293(2008)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ERRATUM