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Index > Protein center > CHST3(Gene name) > Human
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  • CHST3 (Gene name),
  • Carbohydrate sulfotransferase 3 (Protein name ),  CHST3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    CHST3;
    Protein name:
    Carbohydrate sulfotransferase 3;
    Alternative:
    Chondroitin 6-sulfotransferase;Chondroitin 6-O-sulfotransferase 1(C6ST-1);Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0(GST-0);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen.
    Subcellular Location:
    Golgi apparatus membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    479
    Sequence:
    50:
    MEKGLTLPQD | CRDFVHSLKM | RSKYALFLVF | VVIVFVFIEK | ENKIISRVSD | 
    100:
    KLKQIPQALA | DANSTDPALI | LAENASLLSL | SELDSAFSQL | QSRLRNLSLQ | 
    150:
    LGVEPAMEAA | GEEEEEQRKE | EEPPRPAVAG | PRRHVLLMAT | TRTGSSFVGE | 
    200:
    FFNQQGNIFY | LFEPLWHIER | TVSFEPGGAN | AAGSALVYRD | VLKQLFLCDL | 
    250:
    YVLEHFITPL | PEDHLTQFMF | RRGSSRSLCE | DPVCTPFVKK | VFEKYHCKNR | 
    300:
    RCGPLNVTLA | AEACRRKEHM | ALKAVRIRQL | EFLQPLAEDP | RLDLRVIQLV | 
    350:
    RDPRAVLASR | MVAFAGKYKT | WKKWLDDEGQ | DGLREEEVQR | LRGNCESIRL | 
    400:
    SAELGLRQPA | WLRGRYMLVR | YEDVARGPLQ | KAREMYRFAG | IPLTPQVEDW | 
    450:
    IQKNTQAAHD | GSGIYSTQKN | SSEQFEKWRF | SMPFKLAQVV | QAACGPAMRL | 
    479:
    FGYKLARDAA | ALTNRSVSLL | EERGTFWVT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Carbohydrate sulfotransferase 3
    ELISA Kit for Human Carbohydrate sulfotransferase 3
    ELISA Kit for Human Carbohydrate sulfotransferase 3
    ELISA Kit for Human Carbohydrate sulfotransferase 3
    CLIA Kit for Human Carbohydrate sulfotransferase 3
    CLIA Kit for Human Carbohydrate sulfotransferase 3
    CLIA Kit for Human Carbohydrate sulfotransferase 3
    CLIA Kit for Human Carbohydrate sulfotransferase 3
    Polyclonal Antibody for Human Carbohydrate sulfotransferase 3
    Polyclonal Antibody for Human Carbohydrate sulfotransferase 3
    Polyclonal Antibody for Human Carbohydrate sulfotransferase 3
    Polyclonal Antibody for Human Carbohydrate sulfotransferase 3
    Monoclonal Antibody for Human Carbohydrate sulfotransferase 3
    Monoclonal Antibody for Human Carbohydrate sulfotransferase 3
    Monoclonal Antibody for Human Carbohydrate sulfotransferase 3
    Monoclonal Antibody for Human Carbohydrate sulfotransferase 3
    Protein for Human Carbohydrate sulfotransferase 3
    Protein for Human Carbohydrate sulfotransferase 3
    Protein for Human Carbohydrate sulfotransferase 3
    Protein for Human Carbohydrate sulfotransferase 3

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and expression of human chondroitin 6-sulfotransferase."
      Fukuta M. , Kobayashi Y. , Uchimura K. , Kimata K. , Habuchi O.
      Biochim. Biophys. Acta1399:57-61(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
      tissue: Fetal brain.
    2. 2.
      "Functional expression and genomic structure of human chondroitin 6-sulfotransferase."
      Tsutsumi K. , Shimakawa H. , Kitagawa H. , Sugahara K.
      FEBS Lett.441:235-241(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
      tissue: Placenta.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLN-357
      tissue: Liver.
    4. 4.
      "Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement."
      Thiele H. , Sakano M. , Kitagawa H. , Sugahara K. , Rajab A. , Hoehne W. , Ritter H. , Leschik G. , Nuernberg P. , Mundlos S.
      Proc. Natl. Acad. Sci. U.S.A.101:10155-10160(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SEDC-JD GLN-304
    5. 5.
      "Congenital joint dislocations caused by carbohydrate sulfotransferase 3 deficiency in recessive Larsen syndrome and humero-spinal dysostosis."
      Hermanns P. , Unger S. , Rossi A. , Perez-Aytes A. , Cortina H. , Bonafe L. , Boccone L. , Setzu V. , Dutoit M. , Sangiorgi L. , Pecora F. , Reicherter K. , Nishimura G. , Spranger J. , Zabel B. , Superti-Furga A.
      Am. J. Hum. Genet.82:1368-1374(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SEDC-JD TRP-222; PRO-259; PRO-307 AND LYS-372;VARIANT GLN-357;CHARACTERIZATION OF VARIANTS SEDC-JD TRP-222 AND PRO-259
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
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