Cirbp ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCirbp ELISA Kit for Rat(Rattus norvegicus)

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Cirbp (Gene name),

Cold-inducible RNA-binding protein (Protein name ), CIRBP_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Cirbp(Cirp);

Protein name:

Cold-inducible RNA-binding protein;

Alternative:

Glycine-rich RNA-binding protein CIRP;A18 hnRNP;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with EIF4G1. Associates with ribosomes.

Function:

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor. Promotes assembly of stress granules (SGs), when overexpressed.

Subcellular Location:

Nucleus nucleoplasm Cytoplasm Translocates from the nucleus to the cytoplasm after exposure to UV radiation. Translocates from the nucleus to the cytoplasm into stress granules upon various cytoplasmic stresses, such as osmotic and heat shocks. Its recruitment into stress granules occurs in the absence of TIAR proteins.

Protein Attributes:

Sequence length:

172

Sequence:

50:

100:

150:

172:

YGYRSSGGSY | RDSYDSYATH | NE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P60825

UniGene:

Rn.28931

SMR:

P60825

Pfam:

PF00076

Uniprot:

P60825

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ELISA Kit for Rat Cold-inducible RNA-binding protein

Cat.:

E12931r

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96T

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ELISA Kit for Rat Cold-inducible RNA-binding protein

Cat.:

E12931m

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96T

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ELISA Kit for Rat Cold-inducible RNA-binding protein

Cat.:

E12931h

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96T

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CLIA Kit for Rat Cold-inducible RNA-binding protein

Cat.:

U12931m

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Packing:

96T

CLIA Kit for Rat Cold-inducible RNA-binding protein

Cat.:

U12931h

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Packing:

96T

CLIA Kit for Rat Cold-inducible RNA-binding protein

Cat.:

U12931r

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Packing:

96T

Polyclonal Antibody for Rat Cold-inducible RNA-binding protein

Cat.:

P12931Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Cold-inducible RNA-binding protein

Protein for Rat Cold-inducible RNA-binding protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Expression of cold inducible-RNA-binding protein (CIRP) in the rat brain."
Xue J. , Nishiyama H. , Fujita J.
Submitted (1997-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Wistar.
tissue: Testis.

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