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Index > Protein center > CLEC5A(Gene name) > Pig
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  • CLEC5A (Gene name),
  • C-type lectin domain family 5 member A (Protein name ),  CLC5A_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CLEC5A(CLECSF5;MDL1);
    Protein name:
    C-type lectin domain family 5 member A;
    Alternative:
    Myeloid DAP12-associating lectin 1(MDL-1);C-type lectin superfamily member 5;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Monomer (By similarity). Homodimer (By similarity). The majority of CLEC5A is expressed as a monomeric form on macrophages (By similarity). Interacts with TYROBP/DAP12 (By similarity). The interaction with TYROBP is required for CLEC5 cell surface expression (By similarity). Interacts with HCST/DAP10 (By similarity). Forms an CLEC5A/TYROBP/HCST trimolecular complex depending almost solely on TYROBP.
    Function:
    Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation.
    Subcellular Location:
    Cell membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    185
    Sequence:
    50:
    MNWHMIISGL | IVVVLKIVGM | TFFLLYFPQI | FGEHNVSFSP | TERPGTVPQI | 
    100:
    FGSSNVSFTP | TESFGTVCPT | GWDFHQGRCF | FLSTSENSWN | NSMNFCKQKG | 
    150:
    STLAIVNTPE | KLKFLQNISG | AEKYFIGLLY | QPAEKMWRWI | NNSVFNGSVI | 
    185:
    SHSHNFNCVT | IGLTKTFDAA | SCDVNYRSIC | EKSAQ
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Pig C-type lectin domain family 5 member A
    ELISA Kit for Pig C-type lectin domain family 5 member A
    ELISA Kit for Pig C-type lectin domain family 5 member A
    CLIA Kit for Pig C-type lectin domain family 5 member A
    CLIA Kit for Pig C-type lectin domain family 5 member A
    CLIA Kit for Pig C-type lectin domain family 5 member A
    Polyclonal Antibody for Pig C-type lectin domain family 5 member A
    Polyclonal Antibody for Pig C-type lectin domain family 5 member A
    Polyclonal Antibody for Pig C-type lectin domain family 5 member A
    Monoclonal Antibody for Pig C-type lectin domain family 5 member A
    Monoclonal Antibody for Pig C-type lectin domain family 5 member A
    Monoclonal Antibody for Pig C-type lectin domain family 5 member A
    Protein for Pig C-type lectin domain family 5 member A
    Protein for Pig C-type lectin domain family 5 member A
    Protein for Pig C-type lectin domain family 5 member A

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and expression pattern of porcine myeloid DAP12-associating lectin-1."
      Yim D. , Jie H.-B. , Sotiriadis J. , Kim Y.-S. , Kim Y.B.
      Cell. Immunol.209:42-48(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH TYROBP
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