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Index > Protein center > CLCN4(Gene name) > Human
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  • CLCN4 (Gene name),
  • H(+)/Cl(-) exchange transporter 4 (Protein name ),  CLCN4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CLCN4;
    Protein name:
    H(+)/Cl(-) exchange transporter 4;
    Alternative:
    Chloride transporter ClC-4;Chloride channel protein 4(ClC-4);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons.
    Subcellular Location:
    Early endosome membrane Multi-pass membrane protein Late endosome membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    760
    Sequence:
    50:
    MVNAGAMSGS | GNLMDFLDEP | FPDVGTYEDF | HTIDWLREKS | RDTDRHRKIT | 
    100:
    SKSKESIWEF | IKSLLDAWSG | WVVMLLIGLL | AGTLAGVIDL | AVDWMTDLKE | 
    150:
    GVCLSAFWYS | HEQCCWTSNE | TTFEDRDKCP | LWQKWSELLV | NQSEGASAYI | 
    200:
    LNYLMYILWA | LLFAFLAVSL | VRVFAPYACG | SGIPEIKTIL | SGFIIRGYLG | 
    250:
    KWTLLIKTVT | LVLVVSSGLS | LGKEGPLVHV | ACCCGNFFSS | LFSKYSKNEG | 
    300:
    KRREVLSAAA | AAGVSVAFGA | PIGGVLFSLE | EVSYYFPLKT | LWRSFFAALV | 
    350:
    AAFTLRSINP | FGNSRLVLFY | VEYHTPWYMA | ELFPFILLGV | FGGLWGTLFI | 
    400:
    RCNIAWCRRR | KTTRLGKYPV | LEVIVVTAIT | AIIAYPNPYT | RQSTSELISE | 
    450:
    LFNDCGALES | SQLCDYINDP | NMTRPVDDIP | DRPAGVGVYT | AMWQLALALI | 
    500:
    FKIVVTIFTF | GMKIPSGLFI | PSMAVGAIAG | RMVGIGVEQL | AYHHHDWIIF | 
    550:
    RNWCRPGADC | VTPGLYAMVG | AAACLGGVTR | MTVSLVVIMF | ELTGGLEYIV | 
    600:
    PLMAAAVTSK | WVADAFGKEG | IYEAHIHLNG | YPFLDVKDEF | THRTLATDVM | 
    650:
    RPRRGEPPLS | VLTQDSMTVE | DVETLIKETD | YNGFPVVVSR | DSERLIGFAQ | 
    700:
    RRELILAIKN | ARQRQEGIVS | NSIMYFTEEP | PELPANSPHP | LKLRRILNLS | 
    750:
    PFTVTDHTPM | ETVVDIFRKL | GLRQCLVTRS | GRLLGIITKK | DVLRHMAQMA | 
    760:
    NQDPESIMFN | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    KEGG:
    MIM:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human H(+)/Cl(-) exchange transporter 4
    ELISA Kit for Human H(+)/Cl(-) exchange transporter 4
    ELISA Kit for Human H(+)/Cl(-) exchange transporter 4
    CLIA Kit for Human H(+)/Cl(-) exchange transporter 4
    CLIA Kit for Human H(+)/Cl(-) exchange transporter 4
    CLIA Kit for Human H(+)/Cl(-) exchange transporter 4
    Polyclonal Antibody for Human H(+)/Cl(-) exchange transporter 4
    Polyclonal Antibody for Human H(+)/Cl(-) exchange transporter 4
    Polyclonal Antibody for Human H(+)/Cl(-) exchange transporter 4
    Monoclonal Antibody for Human H(+)/Cl(-) exchange transporter 4
    Monoclonal Antibody for Human H(+)/Cl(-) exchange transporter 4
    Monoclonal Antibody for Human H(+)/Cl(-) exchange transporter 4
    Protein for Human H(+)/Cl(-) exchange transporter 4
    Protein for Human H(+)/Cl(-) exchange transporter 4
    Protein for Human H(+)/Cl(-) exchange transporter 4

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Retina.
    2. 2.
      "Identification of an acid-activated Cl- channel from human skeletal muscles."
      Kawasaki M. , Fukuma T. , Yamauchi K. , Sakamoto H. , Marumo F. , Sasaki S.
      Am. J. Physiol.277:C948-C954(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Skeletal muscle.
    3. 3.
      "A chloride channel (ClC-4) in human lens epithelium."
      Rae J.L.
      Submitted (1999-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Lens epithelium.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain.
      tissue: Cerebellum.
    5. 5.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    8. 8.
      "Determinants of anion-proton coupling in mammalian endosomal CLC proteins."
      Zdebik A.A. , Zifarelli G. , Bergsdorf E.-Y. , Soliani P. , Scheel O. , Jentsch T.J. , Pusch M.
      J. Biol. Chem.283:4219-4227(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF GLU-224 AND GLU-281
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