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Index > Protein center > Cldn2(Gene name) > Mouse
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  • Cldn2 (Gene name),
  • Claudin-2 (Protein name ),  CLD2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cldn2;
    Protein name:
    Claudin-2;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
    Function:
    Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
    Subcellular Location:
    Cell junction tight junction Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    230
    Sequence:
    50:
    MASLGVQLVG | YILGLLGLLG | TSIAMLLPNW | RTSSYVGASI | VTAVGFSKGL | 
    100:
    WMECATHSTG | ITQCDIYSTL | LGLPADIQAA | QAMMVTSSAM | SSLACIISVV | 
    150:
    GMRCTVFCQD | SRAKDRVAVV | GGVFFILGGI | LGFIPVAWNL | HGILRDFYSP | 
    200:
    LVPDSMKFEI | GEALYLGIIS | ALFSLVAGVI | LCFSCSPQGN | RTNYYDGYQA | 
    230:
    QPLATRSSPR | SAQQPKAKSE | FNSYSLTGYV | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Claudin-2
    Cat.:
    E11710h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Claudin-2
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse Claudin-2
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse Claudin-2
    Cat.:
    E11710m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Claudin-2
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Claudin-2
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Claudin-2
    Cat.:
    U11710h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Claudin-2
    Cat.:
    U11710m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Claudin-2
    Polyclonal Antibody for Mouse Claudin-2
    Polyclonal Antibody for Mouse Claudin-2
    Cat.:
    P11710Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Claudin-2
    Monoclonal Antibody for Mouse Claudin-2
    Monoclonal Antibody for Mouse Claudin-2
    Monoclonal Antibody for Mouse Claudin-2
    Monoclonal Antibody for Mouse Claudin-2
    Protein for Mouse Claudin-2
    Protein for Mouse Claudin-2
    Protein for Mouse Claudin-2
    Protein for Mouse Claudin-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin."
      Furuse M. , Fujita K. , Hiiragi T. , Fujimoto K. , Tsukita S.
      J. Cell Biol.141:1539-1550(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Liver.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      strain: FVB/N.
      tissue: Brain.
      tissue: Kidney.
    4. 4.
      "Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions."
      Kubota K. , Furuse M. , Sasaki H. , Sonoda N. , Fujita K. , Nagafuchi A. , Tsukita S.
      Curr. Biol.9:1035-1038(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "Manner of interaction of heterogeneous claudin species within and between tight junction strands."
      Furuse M. , Sasaki H. , Tsukita S.
      J. Cell Biol.147:891-903(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CLDN1 AND CLDN3
    6. 6.
      "Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins."
      Itoh M. , Furuse M. , Morita K. , Kubota K. , Saitou M. , Tsukita S.
      J. Cell Biol.147:1351-1363(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TJP1; TJP2 AND TJP3
    7. 7.
      "Cloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alpha."
      Sakaguchi T. , Gu X. , Golden H.M. , Suh E. , Rhoads D.B. , Reinecker H.-C.
      J. Biol. Chem.277:21361-21370(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION
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