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Index > Protein center > Htr2c(Gene name) > Rat
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  • Htr2c (Gene name),
  • 5-hydroxytryptamine receptor 2C (Protein name ),  5HT2C_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Htr2c(5ht1c;Htr1c);
    Protein name:
    5-hydroxytryptamine receptor 2C(5-HT-2C;5-HT2C;5-HTR2C);
    Alternative:
    Serotonin receptor 2C;5-hydroxytryptamine receptor 1C(5-HT-1C;5-HT1C);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with MPDZ. Interacts with ARRB2.
    Function:
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    460
    Sequence:
    50:
    MVNLGNAVRS | LLMHLIGLLV | WQFDISISPV | AAIVTDTFNS | SDGGRLFQFP | 
    100:
    DGVQNWPALS | IVVIIIMTIG | GNILVIMAVS | MEKKLHNATN | YFLMSLAIAD | 
    150:
    MLVGLLVMPL | SLLAILYDYV | WPLPRYLCPV | WISLDVLFST | ASIMHLCAIS | 
    200:
    LDRYVAIRNP | IEHSRFNSRT | KAIMKIAIVW | AISIGVSVPI | PVIGLRDESK | 
    250:
    VFVNNTTCVL | NDPNFVLIGS | FVAFFIPLTI | MVITYFLTIY | VLRRQTLMLL | 
    300:
    RGHTEEELAN | MSLNFLNCCC | KKNGGEEENA | PNPNPDQKPR | RKKKEKRPRG | 
    350:
    TMQAINNEKK | ASKVLGIVFF | VFLIMWCPFF | ITNILSVLCG | KACNQKLMEK | 
    400:
    LLNVFVWIGY | VCSGINPLVY | TLFNKIYRRA | FSKYLRCDYK | PDKKPPVRQI | 
    450:
    PRVAATALSG | RELNVNIYRH | TNERVARKAN | DPEPGIEMQV | ENLELPVNPS | 
    460:
    NVVSERISSV | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat 5-HT-2C
    Cat.:
    E10285r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat 5-HT-2C
    Cat.:
    E10285m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat 5-HT-2C
    Cat.:
    E10285h
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    96T
    ELISA Kit for Rat 5-HT-2C
    Cat.:
    E10285d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat 5-HT-2C
    Cat.:
    U10285r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat 5-HT-2C
    Cat.:
    U10285m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat 5-HT-2C
    Cat.:
    U10285h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat 5-HT-2C
    Cat.:
    U10285d
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat 5-HT-2C
    Polyclonal Antibody for Rat 5-HT-2C
    Cat.:
    P10285Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat 5-HT-2C
    Cat.:
    P10285Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat 5-HT-2C
    Cat.:
    P10285Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat 5-HT-2C
    Monoclonal Antibody for Rat 5-HT-2C
    Monoclonal Antibody for Rat 5-HT-2C
    Monoclonal Antibody for Rat 5-HT-2C
    Protein for Rat 5-HT-2C
    Protein for Rat 5-HT-2C
    Protein for Rat 5-HT-2C
    Protein for Rat 5-HT-2C

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    References
    1. 1.
      "Molecular characterization of a functional cDNA encoding the serotonin 1c receptor."
      Julius D. , McDermott A.B. , Axel R. , Jessell T.M.
      Science241:558-564(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION;SUBCELLULAR LOCATION
    2. 2.
      "Agonist-induced phosphorylation of the serotonin 5-HT2C receptor regulates its interaction with multiple PDZ protein 1."
      Parker L.L. , Backstrom J.R. , Sanders-Bush E. , Shieh B.H.
      J. Biol. Chem.278:21576-21583(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MPDZ;MUTAGENESIS OF SER-458 AND SER-459
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