ABCG1 CLIA Kit for Human(Homo sapiens) | EIAab.comABCG1 CLIA Kit for Human(Homo sapiens)

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ABCG1 (Gene name),

ATP-binding cassette sub-family G member 1 (Protein name ), ABCG1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ABCG1(ABC8;WHT1);

Protein name:

ATP-binding cassette sub-family G member 1;

Alternative:

White protein homolog;ATP-binding cassette transporter 8;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

May form heterodimers with several heterologous partners of the ABCG subfamily.

Function:

Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.

Subcellular Location:

Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes.

Protein Attributes:

Sequence length:

678

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

678:

DFIVLGIFFI | SLRLIAYFVL | RYKIRAER

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF01061

SMR:

P45844

MIM:

603076

KEGG:

hsa:9619

String:

P45844

UniGene:

Hs.124649

Uniprot:

P45844

FOR

ELISA Kit for Human ATP-binding cassette sub-family G member 1

Cat.:

E9149h

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Manual:

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Packing:

96T

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ELISA Kit for Human ATP-binding cassette sub-family G member 1

Cat.:

E9149m

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MSDS:

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Packing:

96T

CLIA Kit for Human ATP-binding cassette sub-family G member 1

Cat.:

U9149m

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MSDS:

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Packing:

96T

CLIA Kit for Human ATP-binding cassette sub-family G member 1

Cat.:

U9149h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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Polyclonal Antibody for Human ATP-binding cassette sub-family G member 1

Cat.:

P9149Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ATP-binding cassette sub-family G member 1

Cat.:

P9149Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human ATP-binding cassette sub-family G member 1

Protein for Human ATP-binding cassette sub-family G member 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3."
Chen H.M. , Rossier C. , Lalioti M.D. , Lynn A. , Chakravarti A. , Perrin G. , Antonarakis S.E.
Am. J. Hum. Genet.59:66-75(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3-678 (ISOFORMS 1 AND 4)
tissue: Retina.
2.

"Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region."
Berry A. , Scott H.S. , Kudoh J. , Talior I. , Korostishevsky M. , Wattenhofer M. , Guipponi M. , Barras C. , Rossier C. , Shibuya K. , Wang J. , Kawasaki K. , Asakawa S. , Minoshima S. , Shimizu N. , Antonarakis S.E. , Bonne-Tamir B.
Genomics68:22-29(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
3.

"The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux."
Porsch-Oezcueruemez M. , Langmann T. , Heimerl S. , Borsukova H. , Kaminski W.E. , Drobnik W. , Honer C. , Schumacher C. , Schmitz G.
J. Biol. Chem.276:12427-12433(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1);REPRESSION BY ZNF202
4.

"Genomic sequence and structure of the human ABCG1 (ABC8) gene."
Lorkowski S. , Rust S. , Engel T. , Jung E. , Tegelkamp K. , Galinski E.A. , Assmann G. , Cullen P.
Biochem. Biophys. Res. Commun.280:121-131(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 2; 3; 4; 5; 6 AND 7)
5.

"Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein."
Kennedy M.A. , Venkateswaran A. , Tarr P.T. , Xenarios I. , Kudoh J. , Shimizu N. , Edwards P.A.
J. Biol. Chem.276:39438-39447(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 8);VARIANT LEU-668
6.

"The DNA sequence of human chromosome 21."
Hattori M. , Fujiyama A. , Taylor T.D. , Watanabe H. , Yada T. , Park H.-S. , Toyoda A. , Ishii K. , Totoki Y. , Choi D.-K. , Groner Y. , Soeda E. , Ohki M. , Takagi T. , Sakaki Y. , Taudien S. , Blechschmidt K. , Polley A. , more...
Nature405:311-319(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (ISOFORM 1)
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
tissue: Brain.
8.

"Isolation and characterization of a mammalian homolog of the Drosophila white gene."
Croop J.M. , Tiller G.E. , Fletcher J.A. , Lux M.L. , Raab E. , Goldenson D. , Son D. , Arciniegas S. , Wu R.
Gene185:77-85(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 33-678
tissue: Fetal brain.
9.

"Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols."
Venkateswaran A. , Repa J.J. , Lobaccaro J.-M.A. , Bronson A. , Mangelsdorf D.J. , Edwards P.A.
J. Biol. Chem.275:14700-14707(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;PROBABLE FUNCTION
10.

"ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport."
Klucken J. , Buechler C. , Orso E. , Kaminski W.E. , Porsch-Oezcueruemez M. , Liebisch G. , Kapinsky M. , Diederich W. , Drobnik W. , Dean M. , Allikmets R. , Schmitz G.
Proc. Natl. Acad. Sci. U.S.A.97:817-822(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;PROBABLE FUNCTION
11.

"Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway."
Kaplan R. , Gan X. , Menke J.G. , Wright S.D. , Cai T.-Q.
J. Lipid Res.43:952-959(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
12.

"Role of ABCG1 and other ABCG family members in lipid metabolism."
Schmitz G. , Langmann T. , Heimerl S.
J. Lipid Res.42:1513-1520(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
13.

"Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease."
Lorkowski S. , Kratz M. , Wenner C. , Schmidt R. , Weitkamp B. , Fobker M. , Reinhardt J. , Rauterberg J. , Galinski E.A. , Cullen P.
Biochem. Biophys. Res. Commun.283:821-830(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
14.

"Antibody-based protein profiling of the human chromosome 21."
Uhlen M. , Oksvold P. , Algenas C. , Hamsten C. , Fagerberg L. , Klevebring D. , Lundberg E. , Odeberg J. , Ponten F. , Kondo T. , Sivertsson A.
Mol. Cell. Proteomics11:0-0(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;MISCELLANEOUS
15.

"Characterization of palmitoylation of ATP binding cassette transporter G1: Effect on protein trafficking and function."
Gu H.M. , Li G. , Gao X. , Berthiaume L.G. , Zhang D.W.
Biochim. Biophys. Acta1831:1067-1078(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-30; CYS-154; CYS-315; CYS-394 AND CYS-406;MUTAGENESIS OF CYS-30; CYS-154; CYS-315; CYS-394 AND CYS-406

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