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Index > Protein center > MLLT3(Gene name) > Human
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  • MLLT3 (Gene name),
  • Protein AF-9 (Protein name ),  AF9_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MLLT3(AF9;YEATS3);
    Protein name:
    Protein AF-9;
    Alternative:
    Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein;ALL1-fused gene from chromosome 9 protein;YEATS domain-containing protein 3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with BCOR. Interacts with CBX8.
    Function:
    N/A
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    568
    Sequence:
    50:
    MASSCAVQVK | LELGHRAQVR | KKPTVEGFTH | DWMVFVRGPE | HSNIQHFVEK | 
    100:
    VVFHLHESFP | RPKRVCKDPP | YKVEESGYAG | FILPIEVYFK | NKEEPRKVRF | 
    150:
    DYDLFLHLEG | HPPVNHLRCE | KLTFNNPTED | FRRKLLKAGG | DPNRSIHTSS | 
    200:
    SSSSSSSSSS | SSSSSSSSSS | SSSSSSSSSS | SSSSSSSSSS | TSFSKPHKLM | 
    250:
    KEHKEKPSKD | SREHKSAFKE | PSRDHNKSSK | ESSKKPKENK | PLKEEKIVPK | 
    300:
    MAFKEPKPMS | KEPKPDSNLL | TITSGQDKKA | PSKRPPISDS | EELSAKKRKK | 
    350:
    SSSEALFKSF | SSAPPLILTC | SADKKQIKDK | SHVKMGKVKI | ESETSEKKKS | 
    400:
    TLPPFDDIVD | PNDSDVEENI | SSKSDSEQPS | PASSSSSSSS | SFTPSQTRQQ | 
    450:
    GPLRSIMKDL | HSDDNEEESD | EVEDNDNDSE | MERPVNRGGS | RSRRVSLSDG | 
    500:
    SDSESSSASS | PLHHEPPPPL | LKTNNNQILE | VKSPIKQSKS | DKQIKNGECD | 
    550:
    KAYLDELVEL | HRRLMTLRER | HILQQIVNLI | EETGHFHITN | TTFDFDLCSL | 
    568:
    DKTTVRKLQS | YLETSGTS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    UniGene:
    KEGG:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein AF-9
    Cat.:
    E15508h
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Protein AF-9
    Cat.:
    E15508m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Protein AF-9
    Cat.:
    U15508h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Protein AF-9
    Cat.:
    U15508m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Protein AF-9
    Cat.:
    P15508Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Protein AF-9
    Cat.:
    P15508Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Protein AF-9
    Monoclonal Antibody for Human Protein AF-9
    Protein for Human Protein AF-9
    Protein for Human Protein AF-9

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs."
      Nakamura T. , Alder H. , Gu Y. , Prasad R. , Canaani O. , Kamada N. , Gale R.P. , Lange B. , Crist W.M. , Nowell P.C. , Croce C.M. , Canaani E.
      Proc. Natl. Acad. Sci. U.S.A.90:4631-4635(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Brain.
      tissue: Synovium.
    3. 3.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Testis.
    6. 6.
      "BCoR, a novel corepressor involved in BCL-6 repression."
      Huynh K.D. , Fischle W. , Verdin E. , Bardwell V.J.
      Genes Dev.14:1810-1823(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BCOR
    7. 7.
      "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3."
      Garcia-Cuellar M.P. , Zilles O. , Schreiner S.A. , Birke M. , Winkler T.H. , Slany R.K.
      Oncogene20:411-419(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CBX8
    8. 8.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-294 AND SER-483;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-288; SER-294 AND SER-483;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-412; SER-419 AND SER-429;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    12. 12.
      "HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription."
      He N. , Liu M. , Hsu J. , Xue Y. , Chou S. , Burlingame A. , Krogan N.J. , Alber T. , Zhou Q.
      Mol. Cell38:428-438(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE SEC COMPLEX
    13. 13.
      "AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia."
      Lin C. , Smith E.R. , Takahashi H. , Lai K.C. , Martin-Brown S. , Florens L. , Washburn M.P. , Conaway J.W. , Conaway R.C. , Shilatifard A.
      Mol. Cell37:429-437(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE SEC COMPLEX
    14. 14.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-483;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    15. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE SEC COMPLEX
    16. 16.
      "The super elongation complex (SEC) family in transcriptional control."
      Luo Z. , Lin C. , Shilatifard A.
      Nat. Rev. Mol. Cell Biol.13:543-547(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON THE SUPER ELONGATION COMPLEX
    17. 17.
      "Human ALKBH4 interacts with proteins associated with transcription."
      Bjornstad L.G. , Meza T.J. , Otterlei M. , Olafsrud S.M. , Meza-Zepeda L.A. , Falnes P.O.
      PLoS ONE7:E49045-E49045(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ALKBH4
    18. 18.
      "Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding."
      Leach B.I. , Kuntimaddi A. , Schmidt C.R. , Cierpicki T. , Johnson S.A. , Bushweller J.H.
      Structure21:176-183(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 490-568 IN COMPLEX WITH AFF1
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