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Index > Protein center > Apba1(Gene name) > Rat
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  • Apba1 (Gene name),
  • Amyloid beta A4 precursor protein-binding family A member 1 (Protein name ),  APBA1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Apba1(Mint1;X11);
    Protein name:
    Amyloid beta A4 precursor protein-binding family A member 1;
    Alternative:
    Neuron-specific X11 protein;Adapter protein X11alpha;Neuronal Munc18-1-interacting protein 1(Mint-1);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Part of a multimeric complex containing Munc18-1 and syntaxin-1. Also part of the brain-specific heterotrimeric complex LIN-10/X11-alpha, LIN-2/CASK, and LIN7. Binds to the cytoplasmic domain of amyloid protein (APP).
    Function:
    Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-AAP.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    839
    Sequence:
    50:
    MNHLEGSAEV | EVADEAPGGE | VNESVEADLE | HPEVEEEQQP | SPPPPAGHAP | 
    100:
    EDHRAHPAPP | PPPPPQEEEE | ERGECLARSA | STESGFHNHT | DTAEGDVLAA | 
    150:
    ARDGYEAERA | QDADDESAYA | VQYRPEAEEY | TEQAEAEHAE | AAQRRALPNH | 
    200:
    LHFHSLEHEE | AMNAAYSGYV | YTHRLFHRAE | DEPYAEPYAD | YGGLQEHVYE | 
    250:
    EIGDAPELEA | RDGLRLYERE | RDEAAAYRQE | ALGARLHHYD | ERSDGESDSP | 
    300:
    EKEAEFAPYP | RMDSYEQEED | IDQIVAEVKQ | SMSSQSLDKA | AEDMPEAEQD | 
    350:
    LERAPTPGGG | HPDSPGLPAP | AGQQQRVVGT | PGGSEVGQRY | SKEKRDAISL | 
    400:
    AIKDIKEAIE | EVKTRTIRSP | YTPDEPKEPI | WVMRQDISPT | RDCDDQRPVD | 
    450:
    GDSPSPGSSS | PLGAESSITP | LHPGDPTEAS | TNKESRKSLA | SFPTYVEVPG | 
    500:
    PCDPEDLIDG | IIFAANYLGS | TQLLSDKTPS | KNVRMMQAQE | AVSRIKTAQK | 
    550:
    LAKSRKKAPE | GESQPMTEVD | LFISTQRIKV | LNADTQEPMM | DHPLRTISYI | 
    600:
    ADIGNIVVLM | ARRRMPRSNS | QENVEASHPS | QDAKRQYKMI | CHVFESEDAQ | 
    650:
    LIAQSIGQAF | SVAYQEFLRA | NGINPEDLSQ | KEYSDLLNTQ | DMYNDDLIHF | 
    700:
    SKSENCKDVF | IEKQKGEILG | VVIVESGWGS | ILPTVIIANM | MHGGPAEKSG | 
    750:
    KLNIGDQIMS | INGTSLVGLP | LSTCQSIIKG | LKNQSRVKLN | IVRCPPVTTV | 
    800:
    LIRRPDLRYQ | LGFSVQNGII | CSLMRGGIAE | RGGVRVGHRI | IEINGQSVVA | 
    839:
    TPHEKIVHIL | SNAVGEIHMK | TMPAAMYRLL | TAQEQPVYI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    SMR:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    E10313r
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    E10313h
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    E10313m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    U10313h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    U10313m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    U10313r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    P10313Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    P10313Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Cat.:
    P10313Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Monoclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Monoclonal Antibody for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Protein for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Protein for Rat Amyloid beta A4 precursor protein-binding family A member 1
    Protein for Rat Amyloid beta A4 precursor protein-binding family A member 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mints, Munc18-interacting proteins in synaptic vesicle exocytosis."
      Okamoto M. , Suedhof T.C.
      J. Biol. Chem.272:31459-31464(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Brain.
    2. 2.
      "A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain."
      Butz S. , Okamoto M. , Suedhof T.C.
      Cell94:773-782(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CASK AND LIN7
      tissue: Testis.
    3. 3.
      "An X11alpha/FSBP complex represses transcription of the GSK3beta gene promoter."
      Lau K.F. , Perkinton M.S. , Rodriguez L. , McLoughlin D.M. , Miller C.C.
      NeuroReport21:761-766(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH FSBP
    4. 4.
      "Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing."
      Matos M.F. , Xu Y. , Dulubova I. , Otwinowski Z. , Richardson J.M. , Tomchick D.R. , Rizo J. , Ho A.
      Proc. Natl. Acad. Sci. U.S.A.109:3802-3807(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 453-643;AUTOINHIBITORY DOMAIN;MUTAGENESIS OF TYR-633;INTERACTION WITH APP
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