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Index > Protein center > ASGR2(Gene name) > Human
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  • ASGR2 (Gene name),
  • Asialoglycoprotein receptor 2 (Protein name ),  ASGR2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    ASGR2(CLEC4H2);
    Protein name:
    Asialoglycoprotein receptor 2(ASGP-R 2;ASGPR 2);
    Alternative:
    Hepatic lectin H2(HL-2);C-type lectin domain family 4 member H2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    The functioning ligand-binding unit of this receptor is thought to be at least a dimer. Interacts with LASS2.
    Function:
    Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    311
    Sequence:
    50:
    MAKDFQDIQQ | LSSEENDHPF | HQGEGPGTRR | LNPRRGNPFL | KGPPPAQPLA | 
    100:
    QRLCSMVCFS | LLALSFNILL | LVVICVTGSQ | SEGHGGAQLQ | AELRSLKEAF | 
    150:
    SNFSSSTLTE | VQAISTHGGS | VGDKITSLGA | KLEKQQQDLK | ADHDALLFHL | 
    200:
    KHFPVDLRFV | ACQMELLHSN | GSQRTCCPVN | WVEHQGSCYW | FSHSGKAWAE | 
    250:
    AEKYCQLENA | HLVVINSWEE | QKFIVQHTNP | FNTWIGLTDS | DGSWKWVDGT | 
    300:
    DYRHNYKNWA | VTQPDNWHGH | ELGGSEDCVE | VQPDGRWNDD | FCLQVYRWVC | 
    311:
    EKRRNATGEV | A
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    UniGene:
    MIM:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human ASGP-R 2
    Cat.:
    E9488h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human ASGP-R 2
    Cat.:
    E9488r
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human ASGP-R 2
    Cat.:
    E9488m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human ASGP-R 2
    Cat.:
    U9488h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ASGP-R 2
    Cat.:
    U9488m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ASGP-R 2
    Cat.:
    U9488r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human ASGP-R 2
    Cat.:
    P9488Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ASGP-R 2
    Cat.:
    P9488Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ASGP-R 2
    Cat.:
    P9488Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ASGP-R 2
    Monoclonal Antibody for Human ASGP-R 2
    Monoclonal Antibody for Human ASGP-R 2
    Protein for Human ASGP-R 2
    Protein for Human ASGP-R 2
    Protein for Human ASGP-R 2

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    References
    1. 1.
      "Sequence of a second human asialoglycoprotein receptor: conservation of two receptor genes during evolution."
      Spiess M. , Lodish H.F.
      Proc. Natl. Acad. Sci. U.S.A.82:6465-6469(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ARG-85
    2. 2.
      "Differences in the abundance of variably spliced transcripts for the second asialoglycoprotein receptor polypeptide, H2, in normal and transformed human liver."
      Paietta E. , Stockert R.J. , Racevskis J.
      Hepatology15:395-402(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ARG-85
      tissue: Liver.
    3. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ARG-85
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Liver.
    5. 6.
      "Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1."
      Pan H. , Qin W.-X. , Huo K.-K. , Wan D.-F. , Yu Y. , Xu Z.-G. , Hu Q.-D. , Gu K.T. , Zhou X.-M. , Jiang H.-Q. , Zhang P.-P. , Huang Y. , Li Y.-Y. , Gu J.-R.
      Genomics77:58-64(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LASS2
    6. 7.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-102
      tissue: Plasma.
    7. 8.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-102 AND ASN-170
      tissue: Liver.
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