Protein name:
Calnexin ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Partial T-cell antigen receptor complexes can escape the ER of immature thymocytes in association with their molecular chaperone to be expressed at low levels on the cell surface where they may function as a signaling complex to regulate thymocyte maturation.
Subcellular Location:
Endoplasmic reticulum membrane
Single-pass type I membrane protein
Melanosome
When bound to CD3 epsilon chains, calnexin's ER retention signal can be masked, permitting it to escape ER retention.
Protein Attributes:
50:
MEGKWLLCLL | LVLGTAAVEA | HDGHDDDAID | IEDDLDDVIE | EVEDSKSKSD |
100:
ASTPPSPKVT | YKAPVPTGEV | YFADSFDRGS | LSGWILSKAK | KDDTDDEIAK |
150:
YDGKWEVDEM | KETKLPGDKG | LVLMSRAKHH | AISAKLNKPF | LFDTKPLIVQ |
200:
YEVNFQNGIE | CGGAYVKLLS | KTAELSLDQF | HDKTPYTIMF | GPDKCGEDYK |
250:
LHFIFRHKNP | KTGVYEEKHA | KRPDADLKTY | FTDKKTHLYT | LILNPDNSFE |
300:
ILVDQSVVNS | GNLLNDMTPP | VNPSREIEDP | EDRKPEDWDE | RPKIADPDAV |
350:
KPDDWDEDAP | SKIPDEEATK | PEGWLDDEPE | YIPDPDAEKP | EDWDEDMDGE |
400:
WEAPQIANPK | CESAPGCGVW | QRPMIDNPNY | KGKWKPPMID | NPNYQGIWKP |
450:
RKIPNPDFFE | DLEPFKMTPF | SAIGLELWSM | TSDIFFDNFI | ISGDRRVVDD |
500:
WANDGWGLKK | AADGAAEPGV | VLQMLEAAEE | RPWLWVVYIL | TVALPVFLVI |
550:
LFCCSGKKQS | NAMEYKKTDA | PQPDVKDEEG | KEEEKNKRDE | EEEEEKLEEK |
591:
QKSDAEEDGV | TGSQDEEDSK | PKAEEDEILN | RSPRNRKPRR | E
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Dog
Mouse
Rat
ELISA Kit for Mouse Calnexin
ELISA Kit for Mouse Calnexin
ELISA Kit for Mouse Calnexin
ELISA Kit for Mouse Calnexin
CLIA Kit for Mouse Calnexin
CLIA Kit for Mouse Calnexin
CLIA Kit for Mouse Calnexin
CLIA Kit for Mouse Calnexin
Polyclonal Antibody for Mouse Calnexin
Polyclonal Antibody for Mouse Calnexin
Polyclonal Antibody for Mouse Calnexin
Polyclonal Antibody for Mouse Calnexin
Monoclonal Antibody for Mouse Calnexin
Monoclonal Antibody for Mouse Calnexin
Monoclonal Antibody for Mouse Calnexin
Monoclonal Antibody for Mouse Calnexin
Protein for Mouse Calnexin
Protein for Mouse Calnexin
Protein for Mouse Calnexin
Protein for Mouse Calnexin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Mammary gland .
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-155
strain :
C57BL/6J .
tissue :
Eye .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 21-591
strain :
BALB/c .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN THYMOCYTE MATURATION;SUBCELLULAR LOCATION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-553;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Teratocarcinoma .
7.
"Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
Munton R.P.
,
Tweedie-Cullen R.
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Livingstone-Zatchej M.
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Mol. Cell. Proteomics6:283-293(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain cortex .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-553; SER-563 AND SER-582;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-582;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH SGIP1