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Index > Protein center > Ccna1(Gene name) > Mouse
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  • Ccna1 (Gene name),
  • Cyclin-A1 (Protein name ),  CCNA1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ccna1;
    Protein name:
    Cyclin-A1;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with INCA1 and KLHDC9 (By similarity). Interacts with the CDK2 and CDC2 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Found in a complex with CDK2, CABLES1 and CCNE1.
    Function:
    May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
    Subcellular Location:
    Nucleus Cytoplasm cytoskeleton spindle In oocytes at least, it associates with the spindle during metaphase.
    Protein Attributes:
    Sequence length:
    421
    Sequence:
    50:
    MHRQSSKSGV | ALPPVGQGPD | ACQMLSRAQL | GQDPPQRTVL | GVLTENEQYR | 
    100:
    RTCGQEITAI | RCFSGSENVF | PAAGKKVLSD | HGVNEPAKRG | FDIYMDDPEQ | 
    150:
    GDRDTCSGKE | GIIFEDVYEV | DTSMLKSDLH | FLLDFNTVSP | MLVDPTTHAQ | 
    200:
    SEEATDFGSD | VINVTEYAEE | IHRYLREAEV | RHRPKAHYMR | KQPDITEGMR | 
    250:
    AILVDWLVEV | GEEYKLRTET | LYLAVNFLDR | FLSCMSVLRG | KLQLVGTAAI | 
    300:
    LLASKYEEIY | PPDVDEFVYI | TDDTYTKRQL | LRMEHLLLKV | LAFDLTVPTT | 
    350:
    NQFLLQYLRR | QGVCIRTENL | AKYVAELSLL | EADPFLKYLP | SLVAAAAYCL | 
    400:
    ANYIVNRHFW | PETLAAFTGY | SLNEIVPCLS | ELHKACLSIP | HRPQQAIREK | 
    421:
    YKASKYLHVS | LMEPPVVLPL | Q
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Cyclin-A1
    Cat.:
    E10115h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Cyclin-A1
    Cat.:
    E10115r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Cyclin-A1
    Cat.:
    E10115m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cyclin-A1
    Cat.:
    U10115r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cyclin-A1
    Cat.:
    U10115h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Cyclin-A1
    Cat.:
    U10115m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Cyclin-A1
    Cat.:
    P10115Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cyclin-A1
    Cat.:
    P10115Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Cyclin-A1
    Cat.:
    P10115Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Cyclin-A1
    Monoclonal Antibody for Mouse Cyclin-A1
    Monoclonal Antibody for Mouse Cyclin-A1
    Protein for Mouse Cyclin-A1
    Protein for Mouse Cyclin-A1
    Protein for Mouse Cyclin-A1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A distinct cyclin A is expressed in germ cells in the mouse."
      Sweeney C. , Murphy M. , Kubelka M. , Ravnik S.E. , Hawkins C.F. , Wolgemuth D.J. , Carrington M.
      Development122:53-64(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Testis.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Testis.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      "Cyclin A1 is required for meiosis in the male mouse."
      Liu D. , Matzuk M.M. , Sung W.K. , Guo Q. , Wang P. , Wolgemuth D.J.
      Nat. Genet.20:377-380(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "Regulation of meiosis during mammalian spermatogenesis: the A-type cyclins and their associated cyclin-dependent kinases are differentially expressed in the germ-cell lineage."
      Ravnik S.E. , Wolgemuth D.J.
      Dev. Biol.207:408-418(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
      strain: Swiss Webster.
    6. 6.
      "Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers."
      Wu C.-L. , Kirley S.D. , Xiao H. , Chuang Y. , Chung D.C. , Zukerberg L.R.
      Cancer Res.61:7325-7332(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH CDK2; CABLES1 AND CCNE1
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