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Index > Protein center > CHAC1(Gene name) > Human
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  • CHAC1 (Gene name),
  • Cation transport regulator-like protein 1 (Protein name ),  CHAC1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CHAC1(BOTCH);
    Protein name:
    Cation transport regulator-like protein 1;
    Alternative:
    Blocks Notch protein(Botch);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Pro-apoptotic component of the unfolded protein response pathway. May mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade.
    Subcellular Location:
    Cytoplasm cytosol
    Protein Attributes:
    Sequence length:
    264
    Sequence:
    50:
    MGGAQLELPS | GARPGVCVRR | SFRAHAGDQP | RRPPGPIPVP | GTMKQESAAP | 
    100:
    NTPPTSQSPT | PSAQFPRNDG | DPQALWIFGY | GSLVWRPDFA | YSDSRVGFVR | 
    150:
    GYSRRFWQGD | TFHRGSDKMP | GRVVTLLEDH | EGCTWGVAYQ | VQGEQVSKAL | 
    200:
    KYLNVREAVL | GGYDTKEVTF | YPQDAPDQPL | KALAYVATPQ | NPGYLGPAPE | 
    250:
    EAIATQILAC | RGFSGHNLEY | LLRLADFMQL | CGPQAQDEHL | AAIVDAVGTM | 
    264:
    LPCFCPTEQA | LALV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cation transport regulator-like protein 1
    Cat.:
    E7513h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Cation transport regulator-like protein 1
    Cat.:
    E7513m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Cation transport regulator-like protein 1
    Cat.:
    E7513r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Cation transport regulator-like protein 1
    Cat.:
    U7513h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cation transport regulator-like protein 1
    Cat.:
    U7513r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cation transport regulator-like protein 1
    Cat.:
    U7513m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Cation transport regulator-like protein 1
    Cat.:
    P7513Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cation transport regulator-like protein 1
    Cat.:
    P7513Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cation transport regulator-like protein 1
    Cat.:
    P7513Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Cation transport regulator-like protein 1
    Monoclonal Antibody for Human Cation transport regulator-like protein 1
    Monoclonal Antibody for Human Cation transport regulator-like protein 1
    Protein for Human Cation transport regulator-like protein 1
    Protein for Human Cation transport regulator-like protein 1
    Protein for Human Cation transport regulator-like protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 9-264 (ISOFORM 1)
      tissue: Liver.
      tissue: Muscle.
    2. 3.
      "Cloning and analyzing of a new chaC like cDNA from human kidney."
      Zheng J.M. , Liu Z.H. , Li L.S.
      Submitted (2004-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 41-264 (ISOFORM 2)
    3. 4.
      "CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascade."
      Mungrue I.N. , Pagnon J. , Kohannim O. , Gargalovic P.S. , Lusis A.J.
      J. Immunol.182:466-476(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION;SUBCELLULAR LOCATION
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 6.
      "Mammalian proapoptotic factor ChaC1 and its homologues function as gamma-glutamyl cyclotransferases acting specifically on glutathione."
      Kumar A. , Tikoo S. , Maity S. , Sengupta S. , Sengupta S. , Kaur A. , Bachhawat A.K.
      EMBO Rep.13:1095-1101(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;MUTAGENESIS OF GLU-157
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