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Index > Protein center > Chac1(Gene name) > Rat
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  • Chac1 (Gene name),
  • Cation transport regulator-like protein 1 (Protein name ),  CHAC1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Chac1(Botch;Npg7);
    Protein name:
    Cation transport regulator-like protein 1;
    Alternative:
    Neuroprotective protein 7;Blocks Notch protein(Botch);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with NOTCH1 (via extracellular region).
    Function:
    Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade.
    Subcellular Location:
    Golgi apparatus Trans-Golgi network Cytoplasm Cytosol
    Protein Attributes:
    Sequence length:
    222
    Sequence:
    50:
    MKQESAAQST | PPPSLSPAPS | AQPSWEDGDP | QALWIFGYGS | LVWKPDFAYS | 
    100:
    DSRVGFVRGY | SRRFWQGDTF | HRGSDKMPGR | VVTLLEDHEG | CTWGVAYQVR | 
    150:
    GEQVSEALKY | LNVREAVLGG | YDTKEVTFYP | QDTPDQPLTA | LAYVATPQNP | 
    200:
    GYLGPAPEEV | IATQILACRG | FSGHNLEYLL | RLADFMQLCG | PQAQDEHLEA | 
    222:
    IVDAVGSLLP | CSYLSEQPLA | LI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Cation transport regulator-like protein 1
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    E7513h
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    96T
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    ELISA Kit for Rat Cation transport regulator-like protein 1
    Cat.:
    E7513m
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    Packing:
    96T
    ELISA Kit for Rat Cation transport regulator-like protein 1
    Cat.:
    E7513r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Cation transport regulator-like protein 1
    Cat.:
    U7513h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Cation transport regulator-like protein 1
    Cat.:
    U7513r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Cation transport regulator-like protein 1
    Cat.:
    U7513m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Cation transport regulator-like protein 1
    Cat.:
    P7513Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Cation transport regulator-like protein 1
    Cat.:
    P7513Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Cation transport regulator-like protein 1
    Cat.:
    P7513Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Cation transport regulator-like protein 1
    Monoclonal Antibody for Rat Cation transport regulator-like protein 1
    Monoclonal Antibody for Rat Cation transport regulator-like protein 1
    Protein for Rat Cation transport regulator-like protein 1
    Protein for Rat Cation transport regulator-like protein 1
    Protein for Rat Cation transport regulator-like protein 1

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    Linearity
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    References
    1. 1.
      "Functional identification of neuroprotective molecules."
      Dai C. , Liang D. , Li H. , Sasaki M. , Dawson T.M. , Dawson V.L.
      PLoS ONE5:E15008-E15008(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: CD Charles River.
    2. 2.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
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