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Index > Protein center > CNNM2(Gene name) > Human
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  • CNNM2 (Gene name),
  • Metal transporter CNNM2 (Protein name ),  CNNM2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CNNM2(ACDP2);
    Protein name:
    Metal transporter CNNM2;
    Alternative:
    Cyclin-M2;Ancient conserved domain-containing protein 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+).
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    875
    Sequence:
    50:
    MIGCGACEPK | VKMAGGQAAA | ALPTWKMAAR | RSLSARGRGI | LQAAAGRLLP | 
    100:
    LLLLSCCCGA | GGCAAVGENE | ETVIIGLRLE | DTNDVSFMEG | GALRVSERTR | 
    150:
    VKLRVYGQNI | NNETWSRIAF | TEHERRRHSP | GERGLGGPAP | PEPDSGPQRC | 
    200:
    GIRTSDIIIL | PHIILNRRTS | GIIEIEIKPL | RKMEKSKSYY | LCTSLSTPAL | 
    250:
    GAGGSGSTGG | AVGGKGGSGV | AGLPPPPWAE | TTWIYHDGED | TKMIVGEEKK | 
    300:
    FLLPFWLQVI | FISLLLCLSG | MFSGLNLGLM | ALDPMELRIV | QNCGTEKEKN | 
    350:
    YAKRIEPVRR | QGNYLLCSLL | LGNVLVNTTL | TILLDDIAGS | GLVAVVVSTI | 
    400:
    GIVIFGEIVP | QAICSRHGLA | VGANTIFLTK | FFMMMTFPAS | YPVSKLLDCV | 
    450:
    LGQEIGTVYN | REKLLEMLRV | TDPYNDLVKE | ELNIIQGALE | LRTKTVEDVM | 
    500:
    TPLRDCFMIT | GEAILDFNTM | SEIMESGYTR | IPVFEGERSN | IVDLLFVKDL | 
    550:
    AFVDPDDCTP | LKTITKFYNH | PLHFVFNDTK | LDAMLEEFKK | GKSHLAIVQR | 
    600:
    VNNEGEGDPF | YEVLGIVTLE | DVIEEIIKSE | ILDETDLYTD | NRTKKKVAHR | 
    650:
    ERKQDFSAFK | QTDSEMKVKI | SPQLLLAMHR | FLATEVEAFS | PSQMSEKILL | 
    700:
    RLLKHPNVIQ | ELKYDEKNKK | APEYYLYQRN | KPVDYFVLIL | QGKVEVEAGK | 
    750:
    EGMKFEASAF | SYYGVMALTA | SPVPLSLSRT | FVVSRTELLA | AGSPGENKSP | 
    800:
    PRPCGLNHSD | SLSRSDRIDA | VTPTLGSSNN | QLNSSLLQVY | IPDYSVRALS | 
    850:
    DLQFVKISRQ | QYQNALMASR | MDKTPQSSDS | ENTKIELTLT | ELHDGLPDET | 
    875:
    ANLLNEQNCV | THSKANHSLH | NEGAI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    UniGene:
    SMR:
    MIM:
    Pfam:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Metal transporter CNNM2
    Cat.:
    E6002r
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    Packing:
    96T
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    ELISA Kit for Human Metal transporter CNNM2
    Cat.:
    E6002m
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    Packing:
    96T
    ELISA Kit for Human Metal transporter CNNM2
    Cat.:
    E6002h
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    Packing:
    96T
    CLIA Kit for Human Metal transporter CNNM2
    Cat.:
    U6002h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Metal transporter CNNM2
    Cat.:
    U6002m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Metal transporter CNNM2
    Cat.:
    U6002r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Metal transporter CNNM2
    Cat.:
    P6002Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Metal transporter CNNM2
    Cat.:
    P6002Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Metal transporter CNNM2
    Cat.:
    P6002Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Metal transporter CNNM2
    Monoclonal Antibody for Human Metal transporter CNNM2
    Monoclonal Antibody for Human Metal transporter CNNM2
    Protein for Human Metal transporter CNNM2
    Protein for Human Metal transporter CNNM2
    Protein for Human Metal transporter CNNM2

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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 242-875 (ISOFORM 1)
      tissue: Colon.
      tissue: Placenta.
      tissue: Teratocarcinoma.
    2. 2.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: B-cell.
    4. 4.
      "Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP)."
      Wang C.-Y. , Shi J.-D. , Yang P. , Kumar P.G. , Li Q.-Z. , Run Q.-G. , Su Y.-C. , Scott H.S. , Kao K.-J. , She J.-X.
      Gene306:37-44(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 210-875 (ISOFORM 1)
    5. 5.
      "CNNM2, encoding a basolateral protein required for renal Mg2+ handling, is mutated in dominant hypomagnesemia."
      Stuiver M. , Lainez S. , Will C. , Terryn S. , Gunzel D. , Debaix H. , Sommer K. , Kopplin K. , Thumfart J. , Kampik N.B. , Querfeld U. , Willnow T.E. , Nemec V. , Wagner C.A. , Hoenderop J.G. , Devuyst O. , Knoers N.V. , Bindels R.J. , more...
      Am. J. Hum. Genet.88:333-343(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;VARIANT HOMG6 ILE-568;CHARACTERIZATION OF VARIANT HOMG6 ILE-568;VARIANT GLN-38
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