Gene name:
Cnnm4 (Acdp4;Kiaa1592) ;
Protein name:
Metal transporter CNNM4 ;
Alternative:
Cyclin-M4 ;Ancient conserved domain-containing protein 4 (mACDP4) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with COX11.
Function:
Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MAPGGGGGRR | DGWPARGRLL | LAALLLLWTR | AASGQSSPQQ | SVILGMRLAS |
100:
CNKSCGMNPD | GIIFVSEGST | VNLRLYGHSL | GDISSNLISF | TEVDDAEAVH |
150:
NSTNCLELTK | DLVVQRLVNV | SRGNTSGMLV | VITKFLRRSE | NMKLYALCTR |
200:
PRADGPWTRW | TDKDSLLFMV | EEHGRFLPLW | LHILLVMVLL | VLSGIFSGLN |
250:
LGLMALDPME | LRIVQNCGTE | KERKYARKIE | PIRRKGNYLL | CSLLLGNVLV |
300:
NTSLTILLDN | LIGSGIMAVA | SSTIGIVIFG | EILPQALCSR | HGLAVGANTI |
350:
VLTKVFMLLT | FPLSFPISKL | LDFVLGQEIR | TVYNREKLME | MLKVTEPYND |
400:
LVKEELNMIQ | GALELRTKTV | EDIMTQLHDC | FMIRSDAILD | FNTMSEIMES |
450:
GYTRIPVFED | EQSNIVDILY | VKDLAFVDPD | DCTPLKTITR | FYNHPVHFVF |
500:
HDTKLDAMLE | EFKKGKSHLA | IVQKVNNEGE | GDPFYEVLGL | VTLEDVIEEI |
550:
IKSEILDESD | MYTDNRTRKR | VSVKNKRDFS | AFKDTDNELK | VKISPQLLLA |
600:
AHRFLATEVP | QFSPSLMSEK | ILLRLLKYPD | VIQELRFNEH | NRYCVRHYLY |
650:
TRNKPADCFV | LILQGKVEVE | AGKENMKFET | GAFSYYGTMA | LSVAPPDRSP |
700:
ALPTPLSRSA | SLSYPDRNTD | LTSTSLAGSN | QFGSCILGQY | VSDFSVRALT |
750:
DLQYIKITRQ | QYQNGLMASR | MDNSPQPTFD | GCATCSENFM | ERPELPPVDE |
771:
TTTLLNERNS | LLHRASEEET | I
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Mouse Metal transporter CNNM4
ELISA Kit for Mouse Metal transporter CNNM4
ELISA Kit for Mouse Metal transporter CNNM4
CLIA Kit for Mouse Metal transporter CNNM4
CLIA Kit for Mouse Metal transporter CNNM4
CLIA Kit for Mouse Metal transporter CNNM4
Polyclonal Antibody for Mouse Metal transporter CNNM4
Polyclonal Antibody for Mouse Metal transporter CNNM4
Polyclonal Antibody for Mouse Metal transporter CNNM4
Monoclonal Antibody for Mouse Metal transporter CNNM4
Monoclonal Antibody for Mouse Metal transporter CNNM4
Monoclonal Antibody for Mouse Metal transporter CNNM4
Protein for Mouse Metal transporter CNNM4
Protein for Mouse Metal transporter CNNM4
Protein for Mouse Metal transporter CNNM4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N.
,
Kikuno R.
,
Ohara R.
,
Inamoto S.
,
Koseki H.
,
Hiraoka S.
,
Saga Y.
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Seino S.
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Nishimura M.
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Kaisho T.
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Hoshino K.
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Kitamura H.
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Nagase T.
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Ohara O.
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Koga H.
DNA Res.11:205-218(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Embryonic tail .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 99-771;TISSUE SPECIFICITY
tissue :
Brain .
3.
"Mutations in CNNM4 cause recessive cone-rod dystrophy with amelogenesis imperfecta."
Polok B.
,
Escher P.
,
Ambresin A.
,
Chouery E.
,
Bolay S.
,
Meunier I.
,
Nan F.
,
Hamel C.
,
Munier F.L.
,
Thilo B.
,
Megarbane A.
,
Schorderet D.F.
Am. J. Hum. Genet.84:259-265(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;FUNCTION
4.
"Mutations in CNNM4 cause Jalili syndrome, consisting of autosomal-recessive cone-rod dystrophy and amelogenesis imperfecta."
Parry D.A.
,
Mighell A.J.
,
El-Sayed W.
,
Shore R.C.
,
Jalili I.K.
,
Dollfus H.
,
Bloch-Zupan A.
,
Carlos R.
,
Carr I.M.
,
Downey L.M.
,
Blain K.M.
,
Mansfield D.C.
,
Shahrabi M.
,
Heidari M.
,
Aref P.
,
Abbasi M.
,
Michaelides M.
,
Moore A.T.
,
Kirkham J.
,
Inglehearn C.F.
more...
Am. J. Hum. Genet.84:266-273(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;FUNCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-661 AND SER-766;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY