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Index > Protein center > C9(Gene name) > Rat
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  • C9 (Gene name),
  • Complement component C9 (Protein name ),  CO9_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    C9;
    Protein name:
    Complement component C9;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Component of the membrane attack complex (MAC). MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9.
    Function:
    Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
    Subcellular Location:
    Secreted Cell membrane Multi-pass membrane protein Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore.
    Protein Attributes:
    Sequence length:
    554
    Sequence:
    50:
    MASGVTITLA | IAIFALEINA | QAPEPTPREE | PSADALLPID | CRMSTWSQWS | 
    100:
    QCDPCLKQRF | RSRSIEVFGQ | FQGKSCADAL | GDRQHCEPTQ | ECEEVQENCG | 
    150:
    NDFQCETGRC | IKRKLLCNGD | NDCGDFSDES | DCESDPRLPC | RDRVVEESEL | 
    200:
    GRTAGYGINI | LGMDPLGTPF | DNEFYNGLCD | RVRDGNTLTY | YRKPWNVAFL | 
    250:
    AYETKADKNF | RTENYEEQFE | MFKTIVRDRT | TSFNANLALK | FTITEAPIKK | 
    300:
    VGVDEVSPEK | NSSKPKDSSV | DFQFSYFKKE | NFQRLSSYLS | QTKKMFLHVK | 
    350:
    GMIQLGRFVM | RNRGVMLTTT | FLDDVKALPV | SYEKGEYFGF | LETYGTHYSS | 
    400:
    SGSLGGLYEL | IYVLDKASMK | EKGVELSDVK | RCLGFNLDVS | LYTPLQTALE | 
    450:
    GPSLTANVNH | SDCLKTGDGK | VVNISRDHII | DDVISFIRGG | TRKQAVLLKE | 
    500:
    KLLRGAKTID | VNDFINWASS | LDDAPALISQ | KLSPIYNLIP | LTMKDAYAKK | 
    550:
    QNMEKAIEDY | VNEFSARKCY | PCQNGGTAIL | LDGQCMCSCT | IKFKGIACEI | 
    554:
    SKQR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Complement component C9
    Cat.:
    E14963h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Complement component C9
    MSDS:
    Please sign in first.
    ELISA Kit for Rat Complement component C9
    MSDS:
    Please sign in first.
    ELISA Kit for Rat Complement component C9
    Cat.:
    E14963m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Complement component C9
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Complement component C9
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Complement component C9
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Complement component C9
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Complement component C9
    Cat.:
    U14963h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Complement component C9
    Cat.:
    U14963m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Complement component C9
    Polyclonal Antibody for Rat Complement component C9
    Polyclonal Antibody for Rat Complement component C9
    Polyclonal Antibody for Rat Complement component C9
    Polyclonal Antibody for Rat Complement component C9
    Monoclonal Antibody for Rat Complement component C9
    Monoclonal Antibody for Rat Complement component C9
    Monoclonal Antibody for Rat Complement component C9
    Monoclonal Antibody for Rat Complement component C9
    Monoclonal Antibody for Rat Complement component C9
    Protein for Rat Complement component C9
    Protein for Rat Complement component C9
    Protein for Rat Complement component C9
    Protein for Rat Complement component C9
    Protein for Rat Complement component C9

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The administration of complement component C9 enhances the survival of neonatal rats with Escherichia coli sepsis."
      Lassiter H.A. , Walz B.M. , Wilson J.L. , Jung E. , Calisi C.R. , Goldsmith L.J. , Wilson R.A. , Morgan B.P. , Feldhoff R.C.
      Pediatr. Res.42:128-136(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
    2. 2.
      "Cloning of rat C9: consequences for homologous restriction of complement."
      Hinchliffe S.J. , Van den Berg C.W. , Rushmere N.K. , Morgan B.P.
      Submitted (1996-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
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