Comt CLIA Kit for Rat(Rattus norvegicus) | EIAab.comComt CLIA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Comt(Gene name) > Rat

Comt (Gene name),

Catechol O-methyltransferase (Protein name ), COMT_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Comt;

Protein name:

Catechol O-methyltransferase;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

N/A

Function:

Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.

Subcellular Location:

Isoform 1 Cell membrane Single-pass type II membrane protein Extracellular side

Protein Attributes:

Sequence length:

264

Sequence:

50:

100:

150:

200:

250:

264:

EKAIYQGPSS | PDKS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P22734

STRING:

10116.ENSRNOP00000043148

UniGene:

Rn.220

String:

P22734

Pfam:

PF01596

KEGG:

rno:24267

Uniprot:

P22734

FOR

ELISA Kit for Rat Catechol O-methyltransferase

Cat.:

E9267h

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Packing:

96T

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ELISA Kit for Rat Catechol O-methyltransferase

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ELISA Kit for Rat Catechol O-methyltransferase

Cat.:

E9267m

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Packing:

96T

ELISA Kit for Rat Catechol O-methyltransferase

Cat.:

E9267r

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96T

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ELISA Kit for Rat Catechol O-methyltransferase

Cat.:

E9267b

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Packing:

96T

CLIA Kit for Rat Catechol O-methyltransferase

Cat.:

U9267b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Catechol O-methyltransferase

Cat.:

U9267m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Catechol O-methyltransferase

MSDS:

Please sign in first.

CLIA Kit for Rat Catechol O-methyltransferase

Cat.:

U9267h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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CLIA Kit for Rat Catechol O-methyltransferase

Cat.:

U9267r

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Packing:

96T

Polyclonal Antibody for Rat Catechol O-methyltransferase

Cat.:

P9267Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Catechol O-methyltransferase

Cat.:

P9267Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Catechol O-methyltransferase

Monoclonal Antibody for Rat Catechol O-methyltransferase

Protein for Rat Catechol O-methyltransferase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Production of rat soluble and membrane-bound catechol O-methyltransferase forms from bifunctional mRNAs."
Tenhunen J. , Ulmanen I.
Biochem. J.296:595-600(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE INITIATION
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Heart.
3.

"Molecular cloning and characterization of rat liver catechol-O-methyltransferase."
Salminen M. , Lundstroem K. , Tilgmann C. , Savolainen R. , Kalkkinen N. , Ulmanen I.
Gene93:241-247(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] OF 11-264
4.

"Cell-free synthesis of rat and human catechol O-methyltransferase. Insertion of the membrane-bound form into microsomal membranes in vitro."
Ulmanen I. , Lundstroem K.
Eur. J. Biochem.202:1013-1020(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-10;CHARACTERIZATION OF THE TWO FORMS
5.

"Crystal structure of catechol O-methyltransferase."
Vidgren J. , Svensson L.A. , Liljas A.
Nature368:354-358(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 44-264
6.

"Structure-based design, synthesis, and in vitro evaluation of bisubstrate inhibitors for catechol O-methyltransferase (COMT)."
Masjost B. , Ballmer P. , Borroni E. , Zuercher G. , Winkler F.K. , Jakob-Roetne R. , Diederich F.
Chemistry6:971-982(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.63 ANGSTROMS) OF 44-264 IN COMPLEX WITH SUBSTRATE ANALOG
7.

"Kinetics and crystal structure of catechol-O-methyltransferase complex with co-substrate and a novel inhibitor with potential therapeutic application."
Bonifacio M.J. , Archer M. , Rodrigues M.L. , Matias P.M. , Learmonth D.A. , Carrondo M.A. , Soares-da-Silva P.
Mol. Pharmacol.62:795-805(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 44-264 IN COMPLEX WITH S-ADENOSYL-L-METHIONINE AND SUBSTRATE ANALOG
8.

"Comparative study of ortho- and meta-nitrated inhibitors of catechol-O-methyltransferase: interactions with the active site and regioselectivity of O-methylation."
Palma P.N. , Rodrigues M.L. , Archer M. , Bonifacio M.J. , Loureiro A.I. , Learmonth D.A. , Carrondo M.A. , Soares-da-Silva P.
Mol. Pharmacol.70:143-153(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 44-264 IN COMPLEX WITH SUBSTRATE ANALOG;BIOPHYSICOCHEMICAL PROPERTIES

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