Protein name:
Malonyl-CoA decarboxylase, mitochondrial (MCD) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced.
Subcellular Location:
Mitochondrion
Cytoplasm
Peroxisome
Protein Attributes:
50:
MRGLGPGLRA | RRLLPLRSPP | RPPGPRGRRL | CGGLAASAMD | ELLRRAVPPT |
100:
PAYELREKTP | APAEGQCADF | VSFYGGLAEA | SQRAELLGRL | AQGFGVDHGQ |
150:
VAEQSAGVLQ | LRQQAREAAV | LLQAEDRLRY | ALVPRYRGLF | HHISKLDGGV |
200:
RFLVQLRADL | LEAQALKLVE | GPHVREMNGV | LKSMLSEWFS | SGFLNLERVT |
250:
WHSPCEVLQK | ISECEAVHPV | KNWMDMKRRV | GPYRRCYFFS | HCSTPGEPLV |
300:
VLHVALTGDI | SNNIQGIVKE | CPPTETEERN | RIAAAIFYSI | SLTQQGLQGV |
350:
ELGTFLIKRV | VKELQKEFPQ | LGAFSSLSPI | PGFTKWLLGL | LNVQGKEHGR |
400:
NELFTDSECQ | EISAVTGNPV | HESLKGFLSS | GEWVKSEKLT | QALQGPLMRL |
450:
CAWYLYGEKH | RGYALNPVAN | FHLQNGAVMW | RINWMADSSL | KGLTSSCGLM |
492:
VNYRYYLEET | GPNSISYLGS | KNIKASEQIL | SLVAQFQNNS | KL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Polyclonal Antibody for Mouse MCD
Polyclonal Antibody for Mouse MCD
Polyclonal Antibody for Mouse MCD
Monoclonal Antibody for Mouse MCD
Monoclonal Antibody for Mouse MCD
Monoclonal Antibody for Mouse MCD
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Cerebellum .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
129 .
strain :
C57BL/6J .
strain :
FVB/N .
tissue :
Mammary tumor .
3.
"Mouse malonyl-CoA decarboxylase: genome structure, cDNA cloning, expression and promoter study."
Kim N.H.
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Lee G.Y.
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Kim Y.S.
Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-175
strain :
129S6/SvEvTac .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;ACETYLATION AT LYS-58; LYS-167; LYS-210; LYS-316; LYS-388; LYS-441 AND LYS-471;MUTAGENESIS OF LYS-471
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-167; LYS-221 AND LYS-385;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
7.
"Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
Rardin M.J.
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-385;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .