EP300 CLIA Kit for Human(Homo sapiens) | EIAab.comEP300 CLIA Kit for Human(Homo sapiens)

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EP300 (Gene name),

Histone acetyltransferase p300 (Protein name ), EP300_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

EP300(P300);

Protein name:

Histone acetyltransferase p300(p300 HAT);

Alternative:

E1A-associated protein p300;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with phosphorylated CREB1 (By similarity). Interacts with HIF1A; the interaction is stimulated in response to hypoxia and inhibited by CITED2. Interacts (via N-terminus) with TFAP2A (via N-terminus); the interaction requires CITED2. Interacts (via CH1 domain) with CITED2 (via C-terminus). Interacts with CITED1 (unphosphorylated form preferentially and via C-terminus). Interacts with ESR1; the interaction is estrogen-dependent and enhanced by CITED1. Interacts with DTX1, EID1, ELF3, FEN1, LEF1, NCOA1, NCOA6, NR3C1, PCAF, PELP1, PRDM6, SP1, SP3, SPIB, SRY, TCF7L2, TP53, SATB1, SRCAP, TTC5, JMY and TRERF1. The TAZ-type 1 domain interacts with HIF1A. Probably part of a complex with HIF1A and CREBBP. Part of a complex containing CARM1 and NCOA2/GRIP1. Interacts with ING4 and this interaction may be indirect. Interacts with ING5. Interacts with the C-terminal region of CITED4. Interacts with HTLV-1 Tax and p30II. Interacts with and acetylates HIV-1 Tat. Non-sumoylated EP300 preferentially interacts with SENP3. Interacts with SS18L1/CREST. Interacts with ALX1 (via homeobox domain). Interacts with NEUROD1; the interaction is inhibited by NR0B2. Interacts with TCF3. Interacts (via CREB-binding domain) with MYOCD (via C-terminus) (By similarity). Binds to HIPK2 (By similarity). Interacts with ROCK2 and PPARG. Forms a complex made of CDK9, CCNT1/cyclin-T1, EP300 and GATA4 that stimulates hypertrophy in cardiomyocytes.

Function:

Functions as histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Acetylates the 'Lys-131' residue of ALX1 and acts as its coactivator in the presence of CREBBP. Acts as a TFAP2A-mediated transcriptional coactivator in presence of CITED2. Plays a role as a coactivator of NEUROD1-dependent transcription of the secretin and p21 genes and controls terminal differentiation of cells in the intestinal epithelium. Promotes cardiac myocyte enlargement.

Subcellular Location:

Cytoplasm Nucleus In the presence of ALX1 relocalizes from the cytoplasm to the nucleus. Co-localizes with ROCK2 in the nucleus.

Protein Attributes:

Sequence length:

2414

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2414:

DLNSNLSQST | LDIH

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00439

SMR:

Q09472

STRING:

9606.ENSP00000263253

KEGG:

hsa:2033

MIM:

602700

String:

Q09472

UniGene:

Hs.517517

Uniprot:

Q09472

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ELISA Kit for Human p300 HAT

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E15334h

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96T

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ELISA Kit for Human p300 HAT

Cat.:

E15334m

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96T

CLIA Kit for Human p300 HAT

Cat.:

U15334m

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96T

CLIA Kit for Human p300 HAT

Cat.:

U15334h

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Packing:

96T

Polyclonal Antibody for Human p300 HAT

Cat.:

P15334Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human p300 HAT

Cat.:

P15334Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human p300 HAT

Protein for Human p300 HAT

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor."
Eckner R. , Ewen M.E. , Newsome D. , Gerdes M. , Decaprio J.A. , Lawrence J.B. , Livingston D.M.
Genes Dev.8:869-884(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PRO-2223
2.

"The DNA sequence of human chromosome 22."
Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"MOZ is fused to p300 in an acute monocytic leukemia with t(8;22)."
Chaffanet M. , Gressin L. , Preudhomme C. , Soenen-Cornu V. , Birnbaum D. , Pebusque M.-J.
Genes Chromosomes Cancer28:138-144(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 27-42;CHROMOSOMAL TRANSLOCATION WITH KAT6A
5.

"Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP."
Lundblad J.R. , Kwok R.P.S. , Laurance M.E. , Harter M.L. , Goodman R.H.
Nature374:85-88(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 552-660
6.

"A transcriptional switch mediated by cofactor methylation."
Xu W. , Chen H. , Du K. , Asahara H. , Tini M. , Emerson B.M. , Montminy M. , Evans R.M.
Science294:2507-2511(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;INTERACTION WITH CARM1;METHYLATION AT ARG-580 AND ARG-604;FUNCTION
7.

"The transcriptional coactivators p300 and CBP are histone acetyltransferases."
Ogryzko V.V. , Schiltz R.L. , Russanova V. , Howard B.H. , Nakatani Y.
Cell87:953-959(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;FUNCTION
8.

"A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A."
Yang X.-J. , Ogryzko V.V. , Nishikawa J. , Howard B.H. , Nakatani Y.
Nature382:319-324(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PCAF
9.

"An essential role for p300/CBP in the cellular response to hypoxia."
Arany Z. , Huang L.E. , Eckner R. , Bhattacharya S. , Jiang C. , Goldberg M.A. , Bunn H.F. , Livingston D.M.
Proc. Natl. Acad. Sci. U.S.A.93:12969-12973(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIF1A AND CREBBP
10.

"Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300."
Bex F. , Yin M.-J. , Burny A. , Gaynor R.B.
Mol. Cell. Biol.18:2392-2405(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTLV-1 TAX
11.

"Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex."
Fryer C.J. , Archer T.K.
Nature393:88-91(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NR3C1
12.

"HIV-1 tat transcriptional activity is regulated by acetylation."
Kiernan R.E. , Vanhulle C. , Schiltz L. , Adam E. , Xiao H. , Maudoux F. , Calomme C. , Burny A. , Nakatani Y. , Jeang K.-T. , Benkirane M. , Van Lint C.
EMBO J.18:6106-6118(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIV-1 TAT
13.

"Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1."
Bhattacharya S. , Michels C.M. , Leung M.K. , Arany Z.P. , Kung A.L. , Livingston D.M.
Genes Dev.13:64-75(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CITED2 AND HIF1A;MUTAGENESIS OF 371-THR--LEU-376 AND 413-VAL--LYS-418
14.

"Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD."
Lau P. , Bailey P. , Dowhan D.H. , Muscat G.E.
Nucleic Acids Res.27:411-420(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RORA
15.

"The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors."
Yahata T. , de Caestecker M.P. , Lechleider R.J. , Andriole S. , Roberts A.B. , Isselbacher K.J. , Shioda T.
J. Biol. Chem.275:8825-8834(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CITED1
16.

"A novel transcriptional repression domain mediates p21(WAF1/CIP1) induction of p300 transactivation."
Snowden A.W. , Anderson L.A. , Webster G.A. , Perkins N.D.
Mol. Cell. Biol.20:2676-2686(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN TRANSCRIPTIONAL REPRESSION
17.

Snowden A.W. , Anderson L.A. , Webster G.A. , Perkins N.D.
Mol. Cell. Biol.20:5360-5360(2000)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
18.

"Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle."
Miyake S. , Sellers W.R. , Safran M. , Li X. , Zhao W. , Grossman S.R. , Gan J. , DeCaprio J.A. , Adams P.D. , Kaelin W.G. Jr.
Mol. Cell. Biol.20:8889-8902(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EID1
19.

"A novel Rb- and p300-binding protein inhibits transactivation by MyoD."
MacLellan W.R. , Xiao G. , Abdellatif M. , Schneider M.D.
Mol. Cell. Biol.20:8903-8915(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EID1
20.

"Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator."
Ko L. , Cardona G.R. , Chin W.W.
Proc. Natl. Acad. Sci. U.S.A.97:6212-6217(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCOA6
21.

"Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones."
Deng L. , de la Fuente C. , Fu P. , Wang L. , Donnelly R. , Wade J.D. , Lambert P. , Li H. , Lee C.-G. , Kashanchi F.
Virology277:278-295(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIV-1 TAT
22.

"Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein."
Yahata T. , Shao W. , Endoh H. , Hur J. , Coser K.R. , Sun H. , Ueda Y. , Kato S. , Isselbacher K.J. , Brown M. , Shioda T.
Genes Dev.15:2598-2612(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ESR1
23.

"Regulation of transcription by AMP-activated protein kinase: phosphorylation of p300 blocks its interaction with nuclear receptors."
Yang W. , Hong Y.H. , Shen X.Q. , Frankowski C. , Camp H.S. , Leff T.
J. Biol. Chem.276:38341-38344(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-89;MUTAGENESIS OF SER-89;INTERACTION WITH PPARG
24.

"Adenovirus DNA binding protein interacts with the SNF2-related CBP activator protein (SrCap) and inhibits SrCap-mediated transcription."
Xu X. , Chackalaparampil I. , Monroy M.A. , Cannella M.T. , Pesek E. , Chrivia J. , Yaciuk P.
J. Virol.75:10033-10040(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SRCAP
25.

"The oncoprotein Tax binds the SRC-1-interacting domain of CBP/p300 to mediate transcriptional activation."
Scoggin K.E.S. , Ulloa A. , Nyborg J.K.
Mol. Cell. Biol.21:5520-5530(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTLV-1 TAX
26.

"Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300."
Zhang W. , Nisbet J.W. , Albrecht B. , Ding W. , Kashanchi F. , Bartoe J.T. , Lairmore M.D.
J. Virol.75:9885-9895(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTLV-1 ACCESSORY PROTEIN P30II
27.

"A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression."
Gizard F. , Lavallee B. , DeWitte F. , Hum D.W.
J. Biol. Chem.276:33881-33892(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRERF1
28.

"Molecular cloning and characterization of PELP1, a novel human coregulator of estrogen receptor alpha."
Vadlamudi R.K. , Wang R.-A. , Mazumdar A. , Kim Y.-S. , Shin J. , Sahin A. , Kumar R.
J. Biol. Chem.276:38272-38279(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PELP1
29.

"Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor."
Yamamoto N. , Yamamoto S. , Inagaki F. , Kawaichi M. , Fukamizu A. , Kishi N. , Matsuno K. , Nakamura K. , Weinmaster G. , Okano H. , Nakafuku M.
J. Biol. Chem.276:45031-45040(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DTX1
30.

"Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300."
Hasan S. , Stucki M. , Hassa P.O. , Imhof R. , Gehrig P. , Hunziker P. , Hubscher U. , Hottiger M.O.
Mol. Cell7:1221-1231(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH FEN1
31.

"Interaction between the hematopoietic Ets transcription factor Spi-B and the coactivator CREB-binding protein associated with negative cross-talk with c-Myb."
Yamamoto H. , Kihara-Negishi F. , Yamada T. , Suzuki M. , Nakano T. , Oikawa T.
Cell Growth Differ.13:69-75(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SPIB
32.

"Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2."
Braganca J. , Swingler T. , Marques F.I.R. , Jones T. , Eloranta J.J. , Hurst H.C. , Shioda T. , Bhattacharya S.
J. Biol. Chem.277:8559-8565(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CITED4
33.

"Synergy among nuclear receptor coactivators: selective requirement for protein methyltransferase and acetyltransferase activities."
Lee Y.-H. , Koh S.S. , Zhang X. , Cheng X. , Stallcup M.R.
Mol. Cell. Biol.22:3621-3632(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH CARM1 AND NCOA2
34.

"Acetylation inactivates the transcriptional repressor BCL6."
Bereshchenko O.R. , Gu W. , Dalla-Favera R.
Nat. Genet.32:606-613(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN BCL6 ACETYLATION
35.

"p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity."
Shiseki M. , Nagashima M. , Pedeux R.M. , Kitahama-Shiseki M. , Miura K. , Okamura S. , Onogi H. , Higashimoto Y. , Appella E. , Yokota J. , Harris C.C.
Cancer Res.63:2373-2378(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ING4 AND ING5
36.

"Identification of a promoter-specific transcriptional activation domain at the C-terminus of the Wnt effector protein T-cell factor 4."
Hecht A. , Stemmler M.P.
J. Biol. Chem.278:3776-3785(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;INTERACTION WITH TCF7L2 AND LEF1
37.

"Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2."
Braganca J. , Eloranta J.J. , Bamforth S.D. , Ibbitt J.C. , Hurst H.C. , Bhattacharya S.
J. Biol. Chem.278:16021-16029(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CITED2 AND TFAP2A;MUTAGENESIS OF ASP-1399
38.

"Acetylated SP3 is a transcriptional activator."
Ammanamanchi S. , Freeman J.W. , Brattain M.G.
J. Biol. Chem.278:35775-35780(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SP3
39.

"P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain."
Iioka T. , Furukawa K. , Yamaguchi A. , Shindo H. , Yamashita S. , Tsukazaki T.
J. Bone Miner. Res.18:1419-1429(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH ALX1
40.

"SATB1 makes a complex with p300 and represses gp91(phox) promoter activity."
Fujii Y. , Kumatori A. , Nakamura M.
Microbiol. Immunol.47:803-811(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SATB1
41.

"P300 transcriptional repression is mediated by SUMO modification."
Girdwood D. , Bumpass D. , Vaughan O.A. , Thain A. , Anderson L.A. , Snowden A.W. , Garcia-Wilson E. , Perkins N.D. , Hay R.T.
Mol. Cell11:1043-1054(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-1020 AND LYS-1024;MUTAGENESIS OF LYS-1020 AND LYS-1024
42.

"Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300."
Rossow K.L. , Janknecht R.
Oncogene22:151-156(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DDX5
43.

"Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53."
An W. , Kim J. , Roeder R.G.
Cell117:735-748(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TP53;FUNCTION
44.

"Regulation of human SRY subcellular distribution by its acetylation/deacetylation."
Thevenet L. , Mejean C. , Moniot B. , Bonneaud N. , Galeotti N. , Aldrian-Herrada G. , Poulat F. , Berta P. , Benkirane M. , Boizet-Bonhoure B.
EMBO J.23:3336-3345(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SRY
45.

"Histone acetyltransferase-dependent chromatin remodeling and the vascular clock."
Curtis A.M. , Seo S.B. , Westgate E.J. , Rudic R.D. , Smyth E.M. , Chakravarti D. , FitzGerald G.A. , McNamara P.
J. Biol. Chem.279:7091-7097(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH NPAS2; ARNTL/BMAL1 AND CLOCK
46.

"Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86."
Wang H. , Fang R. , Cho J.-Y. , Libermann T.A. , Oettgen P.
J. Biol. Chem.279:25241-25250(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ELF3
47.

"Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53."
Dornan D. , Eckert M. , Wallace M. , Shimizu H. , Ramsay E. , Hupp T.R. , Ball K.L.
Mol. Cell. Biol.24:10083-10098(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IRF1
48.

"Regulation of the p300 HAT domain via a novel activation loop."
Thompson P.R. , Wang D. , Wang L. , Fulco M. , Pediconi N. , Zhang D. , An W. , Ge Q. , Roeder R.G. , Wong J. , Levrero M. , Sartorelli V. , Cotter R.J. , Cole P.A.
Nat. Struct. Mol. Biol.11:308-315(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-1499; LYS-1549; LYS-1554; LYS-1558 AND LYS-1560
49.

"Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD."
Kim J.Y. , Chu K. , Kim H.J. , Seong H.A. , Park K.C. , Sanyal S. , Takeda J. , Ha H. , Shong M. , Tsai M.J. , Choi H.S.
Mol. Endocrinol.18:776-790(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NEUROD1 AND TCF3
50.

"Dendrite development regulated by CREST, a calcium-regulated transcriptional activator."
Aizawa H. , Hu S.-C. , Bobb K. , Balakrishnan K. , Ince G. , Gurevich I. , Cowan M. , Ghosh A.
Science303:197-202(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SS18L1/CREST
51.

"Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease."
Roelfsema J.H. , White S.J. , Ariyuerek Y. , Bartholdi D. , Niedrist D. , Papadia F. , Bacino C.A. , den Dunnen J.T. , van Ommen G.-J.B. , Breuning M.H. , Hennekam R.C. , Peters D.J.M.
Am. J. Hum. Genet.76:572-580(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN RSTS2
52.

"SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1."
Bouras T. , Fu M. , Sauve A.A. , Wang F. , Quong A.A. , Perkins N.D. , Hay R.T. , Gu W. , Pestell R.G.
J. Biol. Chem.280:10264-10276(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEACETYLATION BY SIRT1;ACETYLATION AT LYS-1020 AND LYS-1024;MUTAGENESIS OF LYS-1020 AND LYS-1024
53.

"The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription."
Perrot V. , Rechler M.M.
Mol. Endocrinol.19:2283-2298(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FOXO1;FUNCTION;MUTAGENESIS OF ASP-1399
54.

"Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination."
Lee Y.-H. , Coonrod S.A. , Kraus W.L. , Jelinek M.A. , Stallcup M.R.
Proc. Natl. Acad. Sci. U.S.A.102:3611-3616(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METHYLATION AT ARG-2142;CITRULLINATION AT ARG-2142;INTERACTION WITH NCOA2;MUTAGENESIS OF ARG-2056; ARG-2088 AND ARG-2142
55.

"Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase."
Tanaka T. , Nishimura D. , Wu R.C. , Amano M. , Iso T. , Kedes L. , Nishida H. , Kaibuchi K. , Hamamori Y.
J. Biol. Chem.281:15320-15329(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH ROCK2;PHOSPHORYLATION AT SER-89
56.

"The transcriptional activity of CITED1 is regulated by phosphorylation in a cell cycle-dependent manner."
Shi G. , Boyle S.C. , Sparrow D.B. , Dunwoodie S.L. , Shioda T. , de Caestecker M.P.
J. Biol. Chem.281:27426-27435(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CITED1
57.

"Kinetic and mass spectrometric analysis of p300 histone acetyltransferase domain autoacetylation."
Karanam B. , Jiang L. , Wang L. , Kelleher N.L. , Cole P.A.
J. Biol. Chem.281:40292-40301(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-1336 AND LYS-1473;IDENTIFICATION BY MASS SPECTROMETRY
58.

"HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription."
Qiu Y. , Zhao Y. , Becker M. , John S. , Parekh B.S. , Huang S. , Hendarwanto A. , Martinez E.D. , Chen Y. , Lu H. , Adkins N.L. , Stavreva D.A. , Wiench M. , Georgel P.T. , Schiltz R.L. , Hager G.L.
Mol. Cell22:669-679(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN ACETYLATION OF HDAC1
59.

"Sp1 deacetylation induced by phorbol ester recruits p300 to activate 12(S)-lipoxygenase gene transcription."
Hung J.J. , Wang Y.T. , Chang W.C.
Mol. Cell. Biol.26:1770-1785(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SP1
60.

"MTA1, a transcriptional activator of breast cancer amplified sequence 3."
Gururaj A.E. , Singh R.R. , Rayala S.K. , Holm C. , den Hollander P. , Zhang H. , Balasenthil S. , Talukder A.H. , Landberg G. , Kumar R.
Proc. Natl. Acad. Sci. U.S.A.103:6670-6675(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH MTA1
61.

Gururaj A.E. , Singh R.R. , Rayala S.K. , Holm C. , den Hollander P. , Zhang H. , Balasenthil S. , Talukder A.H. , Landberg G. , Kumar R.
Proc. Natl. Acad. Sci. U.S.A.110:4147-4148(2013)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
62.

"Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion."
Ohoka N. , Hattori T. , Kitagawa M. , Onozaki K. , Hayashi H.
J. Biol. Chem.282:35687-35694(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DDIT3
63.

"Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF."
Shin S. , Janknecht R.
J. Cell. Biochem.101:1252-1265(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DDX17
64.

"Acetylation of Sirt2 by p300 attenuates its deacetylase activity."
Han Y. , Jin Y.H. , Kim Y.J. , Kang B.Y. , Choi H.J. , Kim D.W. , Yeo C.Y. , Lee K.Y.
Biochem. Biophys. Res. Commun.375:576-580(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN ACETYLATION OF SIRT2
65.

"PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis."
Wee H.-J. , Voon D.C.-C. , Bae S.-C. , Ito Y.
Blood112:3777-3787(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY HIPK2
66.

"PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation."
Shima Y. , Shima T. , Chiba T. , Irimura T. , Pandolfi P.P. , Kitabayashi I.
Mol. Cell. Biol.28:7126-7138(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FBXO3-MEDIATED DEGRADATION
67.

"The SIRT2 deacetylase regulates autoacetylation of p300."
Black J.C. , Mosley A. , Kitada T. , Washburn M. , Carey M.
Mol. Cell32:449-455(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-418; LYS-423; LYS-1542; LYS-1546; LYS-1549; LYS-1699; LYS-1704 AND LYS-1707;DEACETYLATION BY SIRT2;FUNCTION IN TRANSCRIPTIONAL REGULATION
68.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
69.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
70.

"SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation."
Huang C. , Han Y. , Wang Y. , Sun X. , Yan S. , Yeh E.T.H. , Chen Y. , Cang H. , Li H. , Shi G. , Cheng J. , Tang X. , Yi J.
EMBO J.28:2748-2762(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SENP3;SUMOYLATION
71.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
72.

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-636; LYS-977; LYS-1542; LYS-1546; LYS-1554; LYS-1555; LYS-1558; LYS-1560 AND LYS-1583;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
73.

"Cyclin-dependent kinase-9 is a component of the p300/GATA4 complex required for phenylephrine-induced hypertrophy in cardiomyocytes."
Sunagawa Y. , Morimoto T. , Takaya T. , Kaichi S. , Wada H. , Kawamura T. , Fujita M. , Shimatsu A. , Kita T. , Hasegawa K.
J. Biol. Chem.285:9556-9568(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN COMPLEX WITH CCNT1; CDK9 AND GATA4
74.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
75.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1038;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
76.

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
77.

"Human ALKBH4 interacts with proteins associated with transcription."
Bjornstad L.G. , Meza T.J. , Otterlei M. , Olafsrud S.M. , Meza-Zepeda L.A. , Falnes P.O.
PLoS ONE7:E49045-E49045(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ALKBH4
78.

"Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer."
Tropberger P. , Pott S. , Keller C. , Kamieniarz-Gdula K. , Caron M. , Richter F. , Li G. , Mittler G. , Liu E.T. , Buhler M. , Margueron R. , Schneider R.
Cell152:859-872(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY
79.

"A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters."
Hatzi K. , Jiang Y. , Huang C. , Garrett-Bakelman F. , Gearhart M.D. , Giannopoulou E.G. , Zumbo P. , Kirouac K. , Bhaskara S. , Polo J.M. , Kormaksson M. , Mackerell A.D. Jr. , Xue F. , Mason C.E. , Hiebert S.W. , Prive G.G. , Cerchietti L. , Bardwell V.J. , more...
Cell Rep.4:578-588(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS ACETYLTRANSFERASE OF H3K27
80.

"Kruppel-like factor 15 is critical for vascular inflammation."
Lu Y. , Zhang L. , Liao X. , Sangwung P. , Prosdocimo D.A. , Zhou G. , Votruba A.R. , Brian L. , Han Y.J. , Gao H. , Wang Y. , Shimizu K. , Weinert-Stein K. , Khrestian M. , Simon D.I. , Freedman N.J. , Jain M.K.
J. Clin. Invest.123:4232-4241(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KLF15
81.

"Differential regulation of estrogen receptor alpha expression in breast cancer cells by metastasis-associated protein 1."
Kang H.J. , Lee M.H. , Kang H.L. , Kim S.H. , Ahn J.R. , Na H. , Na T.Y. , Kim Y.N. , Seong J.K. , Lee M.O.
Cancer Res.74:1484-1494(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HDAC4 AND HDAC5
82.

"Constitutive nuclear localization of an alternatively spliced sirtuin-2 isoform."
Rack J.G. , Vanlinden M.R. , Lutter T. , Aasland R. , Ziegler M.
J. Mol. Biol.426:1677-1691(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION;DEACETYLATION BY SIRT2;INTERACTION WITH EP300
83.

"Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha."
Freedman S.J. , Sun Z.-Y.J. , Poy F. , Kung A.L. , Livingston D.M. , Wagner G. , Eck M.J.
Proc. Natl. Acad. Sci. U.S.A.99:5367-5372(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 302-418 IN COMPLEX WITH HIF1A PEPTIDE AND ZINC IONS
84.

"Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2."
Freedman S.J. , Sun Z.Y. , Kung A.L. , France D.S. , Wagner G. , Eck M.J.
Nat. Struct. Biol.10:504-512(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 323-423 IN COMPLEX WITH 216-259 OF CITED2 AND ZINC IONS;INTERACTION WITH CITED2;MUTAGENESIS OF LEU-344 AND LEU-345
85.

"The structural basis of protein acetylation by the p300/CBP transcriptional coactivator."
Liu X. , Wang L. , Zhao K. , Thompson P.R. , Hwang Y. , Marmorstein R. , Cole P.A.
Nature451:846-850(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 1287-1666 IN COMPLEX WITH LYS-COA;MUTAGENESIS OF THR-1357; SER-1396; TYR-1397; GLU-1505; ASP-1625 AND ASP-1628
86.

"Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation."
Feng H. , Jenkins L.M.M. , Durell S.R. , Hayashi R. , Mazur S.J. , Cherry S. , Tropea J.E. , Miller M. , Wlodawer A. , Appella E. , Bai Y.
Structure17:202-210(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1723-1812;INTERACTION WITH TP53
87.

"Histone recognition and large-scale structural analysis of the human bromodomain family."
Filippakopoulos P. , Picaud S. , Mangos M. , Keates T. , Lambert J.P. , Barsyte-Lovejoy D. , Felletar I. , Volkmer R. , Muller S. , Pawson T. , Gingras A.C. , Arrowsmith C.H. , Knapp S.
Cell149:214-231(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.33 ANGSTROMS) OF 1040-1161
88.

"Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation."
Delvecchio M. , Gaucher J. , Aguilar-Gurrieri C. , Ortega E. , Panne D.
Nat. Struct. Mol. Biol.20:1040-1046(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 1043-1519 AND 1581-1666 OF MUTANT PHE-1467 IN COMPLEX WITH ZINC;CATALYTIC ACTIVITY;FUNCTION;AUTOACETYLATION;MUTAGENESIS OF PHE-1170; CYS-1204; GLU-1242; ASP-1399; TYR-1467 AND 1645-ARG-ARG-1646
89.

"Structure of the p300 histone acetyltransferase bound to acetyl-coenzyme A and its analogues."
Maksimoska J. , Segura-Pena D. , Cole P.A. , Marmorstein R.
Biochemistry53:3415-3422(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.94 ANGSTROMS) OF 1287-1664 OF MUTANT PHE-1467 IN COMPLEX WITH ACETYL-COA AND COENZYME A
90.

"Mutations truncating the EP300 acetylase in human cancers."
Gayther S.A. , Batley S.J. , Linger L. , Bannister A. , Thorpe K. , Chin S.-F. , Daigo Y. , Russell P. , Wilson A. , Sowter H.M. , Delhanty J.D.A. , Ponder B.A.J. , Kouzarides T. , Caldas C.
Nat. Genet.24:300-303(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PRO-827; GLY-1013; TYR-1650 AND GLN-2221;POSSIBLE INVOLVEMENT IN CANCER

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