EPHB6 CLIA Kit for Human(Homo sapiens) | EIAab.comEPHB6 CLIA Kit for Human(Homo sapiens)

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EPHB6 (Gene name),

Ephrin type-B receptor 6 (Protein name ), EPHB6_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

EPHB6;

Protein name:

Ephrin type-B receptor 6;

Alternative:

Tyrosine-protein kinase-defective receptor EPH-6;HEP;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with CBL and EPHB1. Interacts with FYN; this interaction takes place in a ligand-independent manner.

Function:

Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.

Subcellular Location:

Isoform 3 Secreted

Protein Attributes:

Sequence length:

1021

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1021:

KLLHHIQLLQ | QHLRQQGSVE | V

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O15197

STRING:

9606.ENSP00000376684

UniGene:

Hs.380089

KEGG:

hsa:2051

MIM:

602757

Pfam:

PF01404

Pfam:

PF14575

SMR:

O15197

Uniprot:

O15197

FOR

ELISA Kit for Human Ephrin type-B receptor 6

Cat.:

E10779h

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Manual:

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Packing:

96T

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ELISA Kit for Human Ephrin type-B receptor 6

Cat.:

E10779r

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MSDS:

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Packing:

96T

ELISA Kit for Human Ephrin type-B receptor 6

Cat.:

E10779m

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Packing:

96T

CLIA Kit for Human Ephrin type-B receptor 6

Cat.:

U10779m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Ephrin type-B receptor 6

Cat.:

U10779r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Ephrin type-B receptor 6

Cat.:

U10779h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Ephrin type-B receptor 6

Cat.:

P10779Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Ephrin type-B receptor 6

Cat.:

P10779Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Ephrin type-B receptor 6

Cat.:

P10779Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Ephrin type-B receptor 6

Protein for Human Ephrin type-B receptor 6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Expression of a kinase-defective Eph-like receptor in the normal human brain."
Matsuoka H. , Iwata N. , Ito M. , Shimoyama M. , Nagata A. , Chihara K. , Takai S. , Matsui T.
Biochem. Biophys. Res. Commun.235:487-492(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
2.

SeattleSNPs variation discovery resource
Submitted (2003-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-122; ARG-282; ALA-324 AND GLN-499
3.

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"Human chromosome 7: DNA sequence and biology."
Scherer S.W. , Cheung J. , MacDonald J.R. , Osborne L.R. , Nakabayashi K. , Herbrick J.-A. , Carson A.R. , Parker-Katiraee L. , Skaug J. , Khaja R. , Zhang J. , Hudek A.K. , Li M. , Haddad M. , Duggan G.E. , Fernandez B.A. , Kanematsu E. , Gentles S. , more...
Science300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Brain.
7.

"Identification of EphB6 variant-derived epitope peptides recognized by cytotoxic T-lymphocytes from HLA-A24+ malignant glioma patients."
Jin M. , Komohara Y. , Shichijo S. , Harada M. , Yamanaka R. , Miyamoto S. , Nikawa J. , Itoh K. , Yamada A.
Oncol. Rep.19:1277-1283(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 16-1021 (ISOFORM 3)
8.

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z. , Henzel W.J.
Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 32-46
9.

"The kinase-null EphB6 receptor undergoes transphosphorylation in a complex with EphB1."
Freywald A. , Sharfe N. , Roifman C.M.
J. Biol. Chem.277:3823-3828(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CBL AND EPHB1;PHOSPHORYLATION
10.

"The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptor-mediated responses."
Freywald A. , Sharfe N. , Rashotte C. , Grunberger T. , Roifman C.M.
J. Biol. Chem.278:10150-10156(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
11.

"Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration."
Matsuoka H. , Obama H. , Kelly M.L. , Matsui T. , Nakamoto M.
J. Biol. Chem.280:29355-29363(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH FYN;PHOSPHORYLATION
12.

"Erythropoietin-producing hepatocyte B6 variant-derived peptides with the ability to induce glioma-reactive cytotoxic T lymphocytes in human leukocyte antigen-A2+ glioma patients."
Jin M. , Komohara Y. , Shichijo S. , Yamanaka R. , Nikawa J. , Itoh K. , Yamada A.
Cancer Sci.99:1656-1662(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
13.

"EphB6 receptor significantly alters invasiveness and other phenotypic characteristics of human breast carcinoma cells."
Fox B.P. , Kandpal R.P.
Oncogene28:1706-1713(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
14.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] ASN-360; PRO-603; GLN-719 AND GLY-930
15.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] SER-122; THR-170; VAL-221; HIS-282; GLN-309; ALA-324; LEU-332; VAL-662; SER-743; HIS-813; LYS-875 AND VAL-993

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