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Index > Protein center > Fscn2(Gene name) > Mouse
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  • Fscn2 (Gene name),
  • Fascin-2 (Protein name ),  FSCN2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Fscn2;
    Protein name:
    Fascin-2;
    Alternative:
    Retinal fascin;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Important for maintaining functional hair-cell bundless in the inner ear. May stiffen the longer stereocilia of hair-cell bundles in the inner ear enabling better force transmission to tip links.
    Subcellular Location:
    Cytoplasm cytoskeleton Cell projection stereocilium Found mostly in longer hair-cell stereocilia and, in all stereocilia, present in gradient with the highest concentration at stereocilia tips.
    Protein Attributes:
    Sequence length:
    492
    Sequence:
    50:
    MPTNGLHQVL | KIQFGLVNDA | DRYLTAESFG | FKVNASAASL | KRKQIWVLEP | 
    100:
    DPGQGTAVLF | RSSHLGRYLS | AEEDGRVACE | MDQPGRDCRF | LVLPQPDGRW | 
    150:
    VLQSEPHGRF | FGGIEDRLSC | FATAISPAEL | WTVHLAIHPQ | AHLLSVSRRR | 
    200:
    YVHLCLQEDE | MAADGDMPWG | VDALVTLIFQ | SRRYCLKSYD | SRYLRSDGRL | 
    250:
    VWEPEAHACY | TLEFKAGKLA | FKDCDGRYLA | PVGPAGTLKA | GRNTRPSKDE | 
    300:
    LFDLEQSHPQ | VVLVAANRRY | ISVRQGINVS | ANQDEELGHE | TFLMQIDQET | 
    350:
    KKCTFYSSTG | GYWTLVTHGG | IQATATQVSA | NTMFEIEWHG | RRVALKASNG | 
    400:
    RFVCMKKNGQ | LAAISDFVGE | DELFTLKLIN | RPLLVLRGLD | GFVCHRRGSN | 
    450:
    QLDTNRSTYD | VFHLSFRDGA | YQIRGRGGGF | WYTGSHGSVC | SDGDLAEDFL | 
    492:
    FEFRERGRLA | IRALSGKYLR | GGASGLLRAD | ADLPVGEALW | EY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Fascin-2
    Cat.:
    E0322h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Fascin-2
    Cat.:
    E0322b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Fascin-2
    Cat.:
    E0322m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Fascin-2
    Cat.:
    U0322m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Fascin-2
    Cat.:
    U0322b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Fascin-2
    Cat.:
    U0322h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse Fascin-2
    Cat.:
    P0322Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Fascin-2
    Polyclonal Antibody for Mouse Fascin-2
    Cat.:
    P0322Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Fascin-2
    Monoclonal Antibody for Mouse Fascin-2
    Monoclonal Antibody for Mouse Fascin-2
    Protein for Mouse Fascin-2
    Protein for Mouse Fascin-2
    Protein for Mouse Fascin-2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Hippocampus.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice."
      Shin J.B. , Longo-Guess C.M. , Gagnon L.H. , Saylor K.W. , Dumont R.A. , Spinelli K.J. , Pagana J.M. , Wilmarth P.A. , David L.L. , Gillespie P.G. , Johnson K.R.
      J. Neurosci.30:9683-9694(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;VARIANT PREBYCUSIS HIS-109
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