GLP1R CLIA Kit for Human(Homo sapiens) | EIAab.comGLP1R CLIA Kit for Human(Homo sapiens)

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GLP1R (Gene name),

Glucagon-like peptide 1 receptor (Protein name ), GLP1R_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

GLP1R;

Protein name:

Glucagon-like peptide 1 receptor(GLP-1 receptor;GLP-1-R;GLP-1R);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

463

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

463:

SSMYTATCQA | SCS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

138032

SMR:

P43220

UniGene:

Hs.389103

String:

P43220

KEGG:

hsa:2740

Pfam:

PF00002

STRING:

9606.ENSP00000362353

Uniprot:

P43220

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ELISA Kit for Human GLP-1 receptor

Cat.:

E10276r

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Packing:

96T

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ELISA Kit for Human GLP-1 receptor

Cat.:

E10276h

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96T

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ELISA Kit for Human GLP-1 receptor

Cat.:

E10276m

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96T

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CLIA Kit for Human GLP-1 receptor

Cat.:

U10276m

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MSDS:

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Packing:

96T

CLIA Kit for Human GLP-1 receptor

Cat.:

U10276h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human GLP-1 receptor

Cat.:

U10276r

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Human GLP-1 receptor

Cat.:

P10276Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human GLP-1 receptor

Protein for Human GLP-1 receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor."
Thorens B. , Porret A. , Buehler L. , Deng S. , Morel P. , Widmann C.
Diabetes42:1678-1682(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PHE-260
tissue: Pancreatic islet.
2.

"Cloning and functional expression of the human glucagon-like peptide-1 (GLP-1) receptor."
Dillon J.S. , Tanizawa Y. , Wheeler M.B. , Leng X. , Ligon B.B. , Rabin D.U. , Yoo-Warren H. , Permutt M. , Boyd A.E.
Endocrinology133:1907-1910(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PHE-260
tissue: Pancreas.
3.

"Cloning and functional expression of a human glucagon-like peptide-1 receptor."
Graziano M.P. , Hey P.J. , Borkowski D. , Chicchi G.C. , Strader C.D.
Biochem. Biophys. Res. Commun.196:141-146(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PHE-260
tissue: Gastric carcinoma.
4.

"Signal transduction of the GLP-1-receptor cloned from a human insulinoma."
van Eyll B. , Lankat-Buttgereit B. , Bode H.P. , Goeke R. , Goeke B.
FEBS Lett.348:7-13(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Insulinoma.
5.

"Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences."
Wei Y. , Mojsov S.
FEBS Lett.358:219-224(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT PHE-260
tissue: Pancreas.
6.

"Genome-wide discovery and analysis of human seven transmembrane helix receptor genes."
Suwa M. , Sato T. , Okouchi I. , Arita M. , Futami K. , Matsumoto S. , Tsutsumi S. , Aburatani H. , Asai K. , Akiyama Y.
Submitted (2001-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

NIEHS SNPs program
Submitted (2003-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LEU-7; LYS-20; HIS-44; GLN-131; SER-168; PHE-260; THR-316; CYS-333 AND GLN-421
8.

"The DNA sequence and analysis of human chromosome 6."
Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT PHE-260
10.

"Cloning and characterization of the 5' flanking sequences (promoter region) of the human GLP-1 receptor gene."
Lankat-Buttgereit B. , Goeke B.
Peptides18:617-624(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-26
tissue: Placenta.
11.

"Functional coupling of Cys-226 and Cys-296 in the glucagon-like peptide-1 (GLP-1) receptor indicates a disulfide bond that is close to the activation pocket."
Mann R.J. , Al-Sabah S. , de Maturana R.L. , Sinfield J.K. , Donnelly D.
Peptides31:2289-2293(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BOND
12.

"Glucagon like-peptide-1 receptor is covalently modified by endogenous mono-ADP-ribosyltransferase."
Dezelak M. , Bavec A.
Mol. Biol. Rep.39:4375-4381(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ADP-RIBOSYLATION AT CYS-341 AND ARG-348
13.

"Regulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerization."
Whitaker G.M. , Lynn F.C. , McIntosh C.H. , Accili E.A.
PLoS ONE7:E32675-E32675(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-63; ASN-82 AND ASN-115;SUBUNIT
14.

"Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain."
Runge S. , Thogersen H. , Madsen K. , Lau J. , Rudolph R.
J. Biol. Chem.283:11340-11347(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 24-145 IN COMPLEX WITH ANTAGONIST EXENDIN-4;DISULFIDE BONDS

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