HSPA8 CLIA Kit for Bovine(Bos taurus) | EIAab.comHSPA8 CLIA Kit for Bovine(Bos taurus)

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HSPA8 (Gene name),

Heat shock cognate 71 kDa protein (Protein name ), HSP7C_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

HSPA8(HSC70);

Protein name:

Heat shock cognate 71 kDa protein;

Alternative:

Heat shock 70 kDa protein 8;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with PACRG. Interacts with HSPH1/HSP105. Interacts with IRAK1BP1 and BAG1. Interacts with DNAJC7. Interacts with CITED1 (via N-terminus); the interaction suppresses the association of CITED1 to p300/CBP and Smad-mediated transcription transactivation.

Function:

Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone.

Subcellular Location:

Cytoplasm Melanosome Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock.

Protein Attributes:

Sequence length:

650

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Bt.12309

STRING:

9913.ENSBTAP00000017497

String:

P19120

Pfam:

PF00012

SMR:

P19120

KEGG:

bta:281831

Uniprot:

P19120

FOR

ELISA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

E1094r

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96T

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ELISA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

E1094c

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96T

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ELISA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

E1094h

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ELISA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

E1094m

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96T

ELISA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

E1094b

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96T

CLIA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

U1094c

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MSDS:

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Packing:

96T

CLIA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

U1094r

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

U1094h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

U1094b

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MSDS:

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Packing:

96T

CLIA Kit for Bovine Heat shock cognate 71 kDa protein

Cat.:

U1094m

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96T

Polyclonal Antibody for Bovine Heat shock cognate 71 kDa protein

Cat.:

P1094Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine Heat shock cognate 71 kDa protein

Cat.:

P1094Rb-h

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40ug/0.2ml

Polyclonal Antibody for Bovine Heat shock cognate 71 kDa protein

Cat.:

P1094Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine Heat shock cognate 71 kDa protein

Monoclonal Antibody for Bovine Heat shock cognate 71 kDa protein

Protein for Bovine Heat shock cognate 71 kDa protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Nucleotide sequence of the cDNA of a bovine 70 kilodalton heat shock cognate protein."
Deluca-Flaherty C. , McKay D.B.
Nucleic Acids Res.18:5569-5569(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain cortex.
2.

"Characterization of 954 bovine full-CDS cDNA sequences."
Harhay G.P. , Sonstegard T.S. , Keele J.W. , Heaton M.P. , Clawson M.L. , Snelling W.M. , Wiedmann R.T. , Van Tassell C.P. , Smith T.P.L.
BMC Genomics6:166-166(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Crossbred X Angus.
tissue: Ileum.
4.

"Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein."
Flaherty K.M. , de Luca-Flaherty C. , McKay D.B.
Nature346:623-628(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 1-385 IN COMPLEX WITH ADP
5.

"Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. II. Structure of the active site with ADP or ATP bound to wild type and mutant ATPase fragment."
Flaherty K.M. , Wilbanks S.M. , Deluca-Flaherty C. , McKay D.B.
J. Biol. Chem.269:12899-12907(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 1-385 IN COMPLEXES WITH ADP AND ATP
6.

"Structural replacement of active site monovalent cations by the epsilon-amino group of lysine in the ATPase fragment of bovine Hsc70."
Wilbanks S.M. , McKay D.B.
Biochemistry37:7456-7462(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 1-385 IN COMPLEX WITH ADP
7.

"The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change."
Sousa M.C. , McKay D.B.
Biochemistry37:15392-15399(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 1-381 IN COMPLEX WITH ADP
8.

"Mapping the role of active site residues for transducing an ATP-induced conformational change in the bovine 70-kDa heat shock cognate protein."
Johnson E.R. , McKay D.B.
Biochemistry38:10823-10830(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 1-381 OF MUTANTS
9.

"Structure of the Hsp110:Hsc70 nucleotide exchange machine."
Schuermann J.P. , Jiang J. , Cuellar J. , Llorca O. , Wang L. , Gimenez L.E. , Jin S. , Taylor A.B. , Demeler B. , Morano K.A. , Hart P.J. , Valpuesta J.M. , Lafer E.M. , Sousa R.
Mol. Cell31:232-243(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.12 ANGSTROMS) OF 2-554 IN COMPLEX WITH ADP

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