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Index > Protein center > Inhba(Gene name) > Mouse
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  • Inhba (Gene name),
  • Inhibin beta A chain (Protein name ),  INHBA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Inhba;
    Protein name:
    Inhibin beta A chain;
    Alternative:
    Activin beta-A chain;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interacts with FST and FSTL3.
    Function:
    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    424
    Sequence:
    50:
    MPLLWLRGFL | LASCWIIVRS | SPTPGSEGHG | SAPDCPSCAL | ATLPKDGPNS | 
    100:
    QPEMVEAVKK | HILNMLHLKK | RPDVTQPVPK | AALLNAIRKL | HVGKVGENGY | 
    150:
    VEIEDDIGRR | AEMNELMEQT | SEIITFAESG | TARKTLHFEI | SKEGSDLSVV | 
    200:
    ERAEVWLFLK | VPKANRTRTK | VTIRLFQQQK | HPQGSLDTGD | EAEEMGLKGE | 
    250:
    RSELLLSEKV | VDARKSTWHI | FPVSSSIQRL | LDQGKSSLDV | RIACEQCQES | 
    300:
    GASLVLLGKK | KKKEVDGDGK | KKDGSDGGLE | EEKEQSHRPF | LMLQARQSED | 
    350:
    HPHRRRRRGL | ECDGKVNICC | KKQFFVSFKD | IGWNDWIIAP | SGYHANYCEG | 
    400:
    ECPSHIAGTS | GSSLSFHSTV | INHYRMRGHS | PFANLKSCCV | PTKLRPMSML | 
    424:
    YYDDGQNIIK | KDIQNMIVEE | CGCS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Inhibin beta A chain
    Cat.:
    E0838h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Inhibin beta A chain
    Cat.:
    E0838m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Inhibin beta A chain
    Cat.:
    E0838r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Inhibin beta A chain
    Cat.:
    E0838p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Inhibin beta A chain
    Cat.:
    E0838b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Inhibin beta A chain
    Cat.:
    E0838c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Inhibin beta A chain
    Cat.:
    U0838b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Inhibin beta A chain
    Cat.:
    U0838p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Inhibin beta A chain
    Cat.:
    U0838r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Inhibin beta A chain
    Cat.:
    U0838m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Inhibin beta A chain
    Cat.:
    U0838h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Inhibin beta A chain
    Cat.:
    U0838c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Inhibin beta A chain
    Polyclonal Antibody for Mouse Inhibin beta A chain
    Cat.:
    P0838Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Inhibin beta A chain
    Cat.:
    P0838Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Inhibin beta A chain
    Cat.:
    P0838Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Inhibin beta A chain
    Polyclonal Antibody for Mouse Inhibin beta A chain
    Monoclonal Antibody for Mouse Inhibin beta A chain
    Monoclonal Antibody for Mouse Inhibin beta A chain
    Monoclonal Antibody for Mouse Inhibin beta A chain
    Monoclonal Antibody for Mouse Inhibin beta A chain
    Monoclonal Antibody for Mouse Inhibin beta A chain
    Monoclonal Antibody for Mouse Inhibin beta A chain
    Protein for Mouse Inhibin beta A chain
    Protein for Mouse Inhibin beta A chain
    Protein for Mouse Inhibin beta A chain
    Protein for Mouse Inhibin beta A chain
    Protein for Mouse Inhibin beta A chain
    Protein for Mouse Inhibin beta A chain

    R&D Technical Data

             12% SDS-PAGE Analysis

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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 7.5%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 9.7%

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    Recovery

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    91-103

    Plasma

    101

    95-107

     

     

     

     

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    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-104%

    93-101%

    95-105%

    91-108%

    EDTA plasma(n=5)

    89-96%

    93-106%

    92-97%

    94-106%

    heparin plasma(n=5)

    93-105%

     

    94-108%

    101-111%

    92-109%

     

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    References
    1. 1.
      "Activins are expressed in preimplantation mouse embryos and in ES and EC cells and are regulated on their differentiation."
      Albano P.M. , Groome N. , Smith J.C.
      Development117:711-723(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N-3.
      tissue: Mammary tumor.
    3. 3.
      "A mesoderm-inducing factor produced by WEHI-3 murine myelomonocytic leukemia cells is activin A."
      Albano R.M. , Godsave S.F. , Huylebroeck D. , Van Nimmen K. , Isaacs H.V. , Slack J.M. , Smith J.C.
      Development110:435-443(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 309-325
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