Gene name:
IREB2 (RCJMB04_5d21) ;
Protein name:
Iron-responsive element-binding protein 2 (IRE-BP 2) ;
Alternative:
Organism:
Chicken (Gallus gallus).
General Annotation
Function:
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MDALRPGSPY | QPIIEELRNY | PQKRFYNVSK | LGGTKYDVLP | YSIRVLFESS |
100:
IRNCDGFLVK | ETDAMNILDW | KTKQNDVEVP | FCPARVVLQD | FTGIPAMVDF |
150:
AAMREAVRNA | GGDPVKVNPA | CPTDLTVDHS | LQIDFSKCAI | QNAPNPGGGE |
200:
AQKPTAKLSP | LKGQPRKLPC | RGQSSCKGPC | SAGELSRASG | QFSAQIENTP |
250:
ILCPFHLQPV | PEPETVLKNQ | EMEFGRNRER | LQFFKWSSKV | FKNTSIIPPE |
300:
TGMAHQVNLE | YLSRVVFDVE | DFLYPDSVVG | TDSHTTMVNG | LGILGWGVGG |
350:
IETEAVMLGM | PVTLTLPEVV | GCELTGTASP | LATSIDIVLG | ITKHLRQAEV |
400:
AGKFVEFFGS | GVSQLSVADR | TTIANMCPEY | GAILSFFPVD | NVTLKHLRHT |
450:
GFDEAKLEVM | EAYLKAVKLF | RNGESSSREP | EYSQVVQISL | SSIIPHVSGP |
500:
KRSQDRVAVN | NMKSDFQTCL | NEKAGVKGFQ | IAAEKQNDVV | PVQYEGNQYE |
550:
LSHGCVVIAA | VISCTNNCNP | SVMLAAGLLA | KKAVEAGLEV | KPYIRTSLSP |
600:
GSGMVTHYLS | SSGVLPYLSK | LGFEVVGYGC | STCVGNTAPL | PEAIRNAIKQ |
650:
GDIIACGVLS | GTKNFEGRLC | DCVRANYLAS | PPLVVAYAIA | GTVRIDFETE |
700:
PLGTGFNGRS | IYLRDIWPTR | KELHTVEEEC | VISSMFKELK | EKMEKGNKRW |
750:
NSLEAPESPL | FPWDLKSTYI | RCPSFFDKLA | KEPVSLQPIE | NAHVLLYLGD |
800:
SVTTDHISPA | GSIARSSAAA | KYLTNKGLTP | REFNSYGARR | GNDAVMTRGT |
850:
FANIKLLNKF | IGKPAPKTIH | FPSGQTLDVF | EAAELYQKEG | IPVIILAGKK |
900:
YGLGSSRDWA | AKGPFLLGVK | AVLAESYEKV | HKSQLIGIGI | APLQFLPGEN |
950:
PNTLGLTGRE | QFSILFPPEL | SPKMTLDIKT | STGKVFSVFA | LFENDVEITL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Rat
Mouse
Pig
ELISA Kit for Chicken IRE-BP 2
ELISA Kit for Chicken IRE-BP 2
ELISA Kit for Chicken IRE-BP 2
ELISA Kit for Chicken IRE-BP 2
ELISA Kit for Chicken IRE-BP 2
CLIA Kit for Chicken IRE-BP 2
CLIA Kit for Chicken IRE-BP 2
CLIA Kit for Chicken IRE-BP 2
CLIA Kit for Chicken IRE-BP 2
CLIA Kit for Chicken IRE-BP 2
Polyclonal Antibody for Chicken IRE-BP 2
Polyclonal Antibody for Chicken IRE-BP 2
Polyclonal Antibody for Chicken IRE-BP 2
Polyclonal Antibody for Chicken IRE-BP 2
Polyclonal Antibody for Chicken IRE-BP 2
Monoclonal Antibody for Chicken IRE-BP 2
Monoclonal Antibody for Chicken IRE-BP 2
Monoclonal Antibody for Chicken IRE-BP 2
Monoclonal Antibody for Chicken IRE-BP 2
Monoclonal Antibody for Chicken IRE-BP 2
Protein for Chicken IRE-BP 2
Protein for Chicken IRE-BP 2
Protein for Chicken IRE-BP 2
Protein for Chicken IRE-BP 2
Protein for Chicken IRE-BP 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis."
Caldwell R.B.
,
Kierzek A.M.
,
Arakawa H.
,
Bezzubov Y.
,
Zaim J.
,
Fiedler P.
,
Kutter S.
,
Blagodatski A.
,
Kostovska D.
,
Koter M.
,
Plachy J.
,
Carninci P.
,
Hayashizaki Y.
,
Buerstedde J.-M.
Genome Biol.6:R6.1-R6.9(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
CB .
tissue :
Bursa of Fabricius .