SPINK1 CLIA Kit for Human(Homo sapiens) | EIAab.comSPINK1 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > SPINK1(Gene name) > Human

SPINK1 (Gene name),

Pancreatic secretory trypsin inhibitor (Protein name ), ISK1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

SPINK1(PSTI);

Protein name:

Pancreatic secretory trypsin inhibitor;

Alternative:

Tumor-associated trypsin inhibitor(TATI);Serine protease inhibitor Kazal-type 1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

Sequence:

50:

79:

GNTYPNECVL | CFENRKRQTS | ILIQKSGPC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:6690

Pfam:

PF00050

UniGene:

Hs.407856

STRING:

9606.ENSP00000296695

String:

P00995

SMR:

P00995

MIM:

167790

Uniprot:

P00995

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ELISA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

E1420h

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96T

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ELISA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

E1420p

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96T

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ELISA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

E1420r

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Packing:

96T

ELISA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

E1420b

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96T

ELISA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

E1420d

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96T

CLIA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

U1420p

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96T

CLIA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

U1420r

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Packing:

96T

CLIA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

U1420b

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Packing:

96T

CLIA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

U1420h

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Packing:

96T

CLIA Kit for Human Pancreatic secretory trypsin inhibitor

Cat.:

U1420d

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96T

Polyclonal Antibody for Human Pancreatic secretory trypsin inhibitor

Cat.:

P1420Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Pancreatic secretory trypsin inhibitor

Cat.:

P1420Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Pancreatic secretory trypsin inhibitor

Monoclonal Antibody for Human Pancreatic secretory trypsin inhibitor

Protein for Human Pancreatic secretory trypsin inhibitor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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Citations

[1].

"Serine protease inhibitor Kazal type 1 promotes epithelial–mesenchymal transition through EGFR signaling pathway in prostate cancer"

C Wang, L Wang, B Su, et al.

From:The Prostate

References

1.

"Primary structure of human pancreatic secretory trypsin inhibitor (PSTI) gene."
Horii A. , Kobayashi T. , Tomita N. , Yamamoto T. , Fukushige S. , Murotsu T. , Ogawa M. , Mori T. , Matsubara K.
Biochem. Biophys. Res. Commun.149:635-641(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Molecular cloning and nucleotide sequence of human pancreatic secretory trypsin inhibitor (PSTI) cDNA."
Yamamoto T. , Nakamura Y. , Nishide T. , Emi M. , Ogawa M. , Mori T. , Matsubara K.
Biochem. Biophys. Res. Commun.132:605-612(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Expression of pancreatic secretory trypsin inhibitor gene in neoplastic tissues."
Tomita N. , Horii A. , Yamamoto T. , Ogawa M. , Mori T. , Matsubara K.
FEBS Lett.225:113-119(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis."
Witt H. , Luck W. , Hennies H.C. , Classen M. , Kage A. , Lass U. , Landt O. , Becker M.
Nat. Genet.25:213-216(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS PCTT PRO-14 AND SER-34;VARIANT SER-55
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pancreas.
tissue: Spleen.
6.

"The primary structure of the human pancreatic secretory trypsin inhibitor. Amino acid sequence of the reduced S-aminoethylated protein."
Bartelt D.C. , Shapanka R. , Greene L.J.
Arch. Biochem. Biophys.179:189-199(1977) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-79
7.

"Purification and characterization of a tumor-associated trypsin inhibitor from the urine of a patient with ovarian cancer."
Huhtala M.-L. , Pesonen K. , Kalkkinen N. , Stenman U.-H.
J. Biol. Chem.257:13713-13716(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-46
8.

"Three-dimensional structure of a recombinant variant of human pancreatic secretory trypsin inhibitor (Kazal type)."
Hecht H.-J. , Szardenings M. , Collins J. , Schomburg D.
J. Mol. Biol.225:1095-1103(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS)
9.

"Solution structure of a variant of human pancreatic secretory trypsin inhibitor determined by nuclear magnetic resonance spectroscopy."
Klaus W. , Schomburg D.
J. Mol. Biol.229:695-706(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF MUTANT LEU-41/ARG-44
10.

"Mutational analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene in hereditary and sporadic chronic pancreatitis."
Chen J.-M. , Mercier B. , Audrezet M.-P. , Ferec C.
J. Med. Genet.37:67-69(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PCTT SER-34;VARIANT SER-55
11.

"SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent."
Hassan Z. , Mohan V. , Ali L. , Allotey R. , Barakat K. , Faruque M.O. , Deepa R. , McDermott M.F. , Jackson A.E. , Cassell P. , Curtis D. , Gelding S.V. , Vijayaravaghan S. , Gyr N. , Whitcomb D.C. , Azad Khan A.K. , Hitman G.A.
Am. J. Hum. Genet.71:964-968(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TCP SER-34;INVOLVEMENT IN FIBROCALCULOUS PANCREATIC DIABETES
12.

"Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis."
Chandak G.R. , Idris M.M. , Reddy D.N. , Bhaskar S. , Sriram P.V.J. , Singh L.
J. Med. Genet.39:347-351(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TCP SER-34;VARIANT SER-55
13.

"Gene symbol: Spink1-Omim 167790. Disease: hereditary pancreatitis."
Deybach J.-C.D. , Phung L. , Lamoril J. , Bouizegarene P. , Levy P. , Deybach J.-C. , Ruszniewski P.
Hum. Genet.113:369-369(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PCTT PHE-12

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