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Index > Protein center > LALBA(Gene name) > Human
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  • LALBA (Gene name),
  • Alpha-lactalbumin (Protein name ),  LALBA_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LALBA(LYZL7);
    Protein name:
    Alpha-lactalbumin;
    Alternative:
    Lysozyme-like protein 7;Lactose synthase B protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA).
    Function:
    Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    142
    Sequence:
    50:
    MRFFVPLFLV | GILFPAILAK | QFTKCELSQL | LKDIDGYGGI | ALPELICTMF | 
    100:
    HTSGYDTQAI | VENNESTEYG | LFQISNKLWC | KSSQVPQSRN | ICDISCDKFL | 
    142:
    DDDITDDIMC | AKKILDIKGI | DYWLAHKALC | TEKLEQWLCE | KL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    KEGG:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha-lactalbumin
    Cat.:
    E1018h
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    96T
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    ELISA Kit for Human Alpha-lactalbumin
    Cat.:
    E1018b
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    96T
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    ELISA Kit for Human Alpha-lactalbumin
    Cat.:
    E1018m
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    96T
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    ELISA Kit for Human Alpha-lactalbumin
    MSDS:
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    ELISA Kit for Human Alpha-lactalbumin
    Cat.:
    E1018p
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    Packing:
    96T
    ELISA Kit for Human Alpha-lactalbumin
    Cat.:
    E1018r
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    Packing:
    96T
    ELISA Kit for Human Alpha-lactalbumin
    Cat.:
    E1018d
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    Packing:
    96T
    CLIA Kit for Human Alpha-lactalbumin
    Cat.:
    U1018r
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    Packing:
    96T
    CLIA Kit for Human Alpha-lactalbumin
    Cat.:
    U1018d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Alpha-lactalbumin
    Cat.:
    U1018m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Alpha-lactalbumin
    Cat.:
    U1018p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Alpha-lactalbumin
    Cat.:
    U1018b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Alpha-lactalbumin
    MSDS:
    Please sign in first.
    CLIA Kit for Human Alpha-lactalbumin
    Cat.:
    U1018h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    Polyclonal Antibody for Human Alpha-lactalbumin
    Polyclonal Antibody for Human Alpha-lactalbumin
    Cat.:
    P1018Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Alpha-lactalbumin
    Cat.:
    P1018Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Alpha-lactalbumin
    Polyclonal Antibody for Human Alpha-lactalbumin
    Polyclonal Antibody for Human Alpha-lactalbumin
    Polyclonal Antibody for Human Alpha-lactalbumin
    Cat.:
    P1018Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Alpha-lactalbumin
    Monoclonal Antibody for Human Alpha-lactalbumin
    Monoclonal Antibody for Human Alpha-lactalbumin
    Monoclonal Antibody for Human Alpha-lactalbumin
    Monoclonal Antibody for Human Alpha-lactalbumin
    Monoclonal Antibody for Human Alpha-lactalbumin
    Monoclonal Antibody for Human Alpha-lactalbumin
    Protein for Human Alpha-lactalbumin
    Protein for Human Alpha-lactalbumin
    Protein for Human Alpha-lactalbumin
    Protein for Human Alpha-lactalbumin
    Protein for Human Alpha-lactalbumin
    Protein for Human Alpha-lactalbumin
    Protein for Human Alpha-lactalbumin

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    References
    1. 1.
      "Comparison of the nucleotide sequence of cloned human and guinea-pig pre-alpha-lactalbumin cDNA with that of chick pre-lysozyme cDNA suggests evolution from a common ancestral gene."
      Hall L. , Craig R.K. , Edbrooke M.R. , Campbell P.N.
      Nucleic Acids Res.10:3503-3515(1982) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Organization and sequence of the human alpha-lactalbumin gene."
      Hall L. , Emery D.C. , Davies M.S. , Parker D. , Craig R.K.
      Biochem. J.242:735-742(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Analysis of flanking sequence of human alpha-lactalbumin containing a putative locus control region."
      Fujiwara Y. , Takahashi R. , Hirabayashi M. , Ueda M. , Muramatsu T. , Yamanaka H. , Sekikawa K.
      Submitted (2000-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    7. 7.
      "The complete amino-acid sequence of human alpha-lactalbumin."
      Findlay J.B.C. , Brew K.
      Eur. J. Biochem.27:65-86(1972) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-142
    8. 8.
      "Identification of a new molecular form of human alpha-lactalbumin."
      Maynard F.
      J. Dairy Res.59:425-429(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 78-81 AND 90-112
      tissue: Milk.
    9. 9.
      "An unusual glycosylation site in alpha-lactalbumin from human milk."
      Cavaletto M. , Giuffrida M.G. , Giunta C. , Conti A.
      Protein Sci. 4 Suppl.1:119-119(1995)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-90
    10. 10.
      "Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry."
      Picariello G. , Ferranti P. , Mamone G. , Roepstorff P. , Addeo F.
      Proteomics8:3833-3847(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-64
      tissue: Milk.
    11. 11.
      "Crystal structure of human alpha-lactalbumin at 1.7-A resolution."
      Acharya K.R. , Ren J.S. , Stuart D.I. , Phillips D.C. , Fenna R.E.
      J. Mol. Biol.221:571-581(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS)
    12. 12.
      "Alpha-lactalbumin possesses a distinct zinc binding site."
      Ren J.S. , Stuart D.I. , Acharya K.R.
      J. Biol. Chem.268:19292-19298(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS)
    13. 13.
      "Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin."
      Chandra N. , Brew K. , Acharya K.R.
      Biochemistry37:4767-4772(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS)
    14. 14.
      "Crystallographic evaluation of internal motion of human alpha-lactalbumin refined by full-matrix least-squares method."
      Harata K. , Abe Y. , Muraki M.
      J. Mol. Biol.287:347-358(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS)
    15. 15.
      "Detection of a single nucleotide polymorphism in the human alpha-lactalbumin gene: implications for human milk proteins."
      Chowanadisai W. , Kelleher S.L. , Nemeth J.F. , Yachetti S. , Kuhlman C.F. , Jackson J.G. , Davis A.M. , Lien E.L. , Loennerdal B.
      J. Nutr. Biochem.16:272-278(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT VAL-46;IDENTIFICATION BY MASS SPECTROMETRY
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