LOXL2 CLIA Kit for Bovine(Bos taurus) | EIAab.comLOXL2 CLIA Kit for Bovine(Bos taurus)

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LOXL2 (Gene name),

Lysyl oxidase homolog 2 (Protein name ), LOXL2_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LOXL2;

Protein name:

Lysyl oxidase homolog 2;

Alternative:

Lysyl oxidase-like protein 2;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Component of some chromatin repressor complex. Interacts with SNAI1.

Function:

Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.

Subcellular Location:

Secreted Extracellular space Extracellular matrix Basement membrane Nucleus Chromosome Associated with chromatin (By similarity). It is unclear how LOXL2 is nuclear: it contains a clear signal sequence and is predicted to localize in the extracellular medium. However, different reports confirmed the intracellular location and its key role in transcription regulation.

Protein Attributes:

Sequence length:

774

Sequence:

50:

100:

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250:

300:

350:

400:

450:

500:

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650:

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750:

774:

SFSEETEKKF | EHFSGLINNQ | VSKR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Bt.3041

STRING:

9913.ENSBTAP00000008159

KEGG:

bta:532684

Pfam:

PF01186

Uniprot:

A6H737

FOR

ELISA Kit for Bovine Lysyl oxidase homolog 2

Cat.:

E14939h

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96T

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ELISA Kit for Bovine Lysyl oxidase homolog 2

MSDS:

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ELISA Kit for Bovine Lysyl oxidase homolog 2

MSDS:

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ELISA Kit for Bovine Lysyl oxidase homolog 2

Cat.:

E14939r

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ELISA Kit for Bovine Lysyl oxidase homolog 2

Cat.:

E14939m

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CLIA Kit for Bovine Lysyl oxidase homolog 2

Cat.:

U14939h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Bovine Lysyl oxidase homolog 2

MSDS:

Please sign in first.

CLIA Kit for Bovine Lysyl oxidase homolog 2

MSDS:

Please sign in first.

CLIA Kit for Bovine Lysyl oxidase homolog 2

MSDS:

Please sign in first.

CLIA Kit for Bovine Lysyl oxidase homolog 2

Cat.:

U14939m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Bovine Lysyl oxidase homolog 2

Monoclonal Antibody for Bovine Lysyl oxidase homolog 2

Protein for Bovine Lysyl oxidase homolog 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"A whole-genome assembly of the domestic cow, Bos taurus."
Zimin A.V. , Delcher A.L. , Florea L. , Kelley D.R. , Schatz M.C. , Puiu D. , Hanrahan F. , Pertea G. , Van Tassell C.P. , Sonstegard T.S. , Marcais G. , Roberts M. , Subramanian P. , Yorke J.A. , Salzberg S.L.
Genome Biol.10:R42.01-R42.10(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: Hereford.
2.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2007-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Fetal skin.

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