Protein name:
Latent-transforming growth factor beta-binding protein 4 (LTBP-4) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Forms part of the large latent transforming growth factor beta precursor complex; removal is essential for activation of complex. Interacts with LTBP1 and TGFB1. Binds to FBN1.
Function:
May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).
Subcellular Location:
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MPRPGTSGRR | PLLLVLLLPL | FAAATSAASP | SPSPSQVVEV | PGVPSRPASV |
100:
AVCRCCPGQT | SRRSRCIRAF | CRVRSCQPKK | CAGPQRCLNP | VPAVPSPSPS |
150:
VRKRQVSLNW | QPLTLQEARA | LLKRRRPRGP | GGRGLLRRRP | PQRAPAGKAP |
200:
VLCPLICHNG | GVCVKPDRCL | CPPDFAGKFC | QLHSSGARPP | APAVPGLTRS |
250:
VYTMPLANHR | DDEHGVASMV | SVHVEHPQEA | SVVVHQVERV | SGPWEEADAE |
300:
AVARAEAAAR | AEAAAPYTVL | AQSAPREDGY | SDASGFGYCF | RELRGGECAS |
350:
PLPGLRTQEV | CCRGAGLAWG | VHDCQLCSER | LGNSERVSAP | DGPCPTGFER |
400:
VNGSCEDVDE | CATGGRCQHG | ECANTRGGYT | CVCPDGFLLD | SSRSSCISQH |
450:
VISEAKGPCF | RVLRDGGCSL | PILRNITKQI | CCCSRVGKAW | GRGCQLCPPF |
500:
GSEGFREICP | AGPGYHYSAS | DLRYNTRPLG | QEPPRVSLSQ | PRTLPATSRP |
550:
SAGFLPTHRL | EPRPEPRPDP | RPGPELPLPS | IPAWTGPEIP | ESGPSSGMCQ |
600:
RNPQVCGPGR | CISRPSGYTC | ACDSGFRLSP | QGTRCIDVDE | CRRVPPPCAP |
650:
GRCENSPGSF | RCVCGPGFRA | GPRAAECLDV | DECHRVPPPC | DLGRCENTPG |
700:
SFLCVCPAGY | QAAPHGASCQ | DVDECTQSPG | LCGRGACKNL | PGSFRCVCPA |
750:
GFRGSACEED | VDECAQEPPP | CGPGRCDNTA | GSFHCACPAG | FRSRGPGAPC |
800:
QDVDECARSP | PPCTYGRCEN | TEGSFQCVCP | MGFQPNTAGS | ECEDVDECEN |
850:
HLACPGQECV | NSPGSFQCRT | CPSGHHLHRG | RCTDVDECSS | GAPPCGPHGH |
900:
CTNTEGSFRC | SCAPGYRAPS | GRPGPCADVN | ECLEGDFCFP | HGECLNTDGS |
950:
FACTCAPGYR | PGPRGASCLD | VDECSEEDLC | QSGICTNTDG | SFECICPPGH |
1000:
RAGPDLASCL | DVDECRERGP | ALCGSQRCEN | SPGSYRCVRD | CDPGYHAGPE |
1050:
GTCDDVDECQ | EYGPEICGAQ | RCENTPGSYR | CTPACDPGYQ | PTPGGGCQDV |
1100:
DECRNRSFCG | AHAVCQNLPG | SFQCLCDQGY | EGARDGRHCV | DVNECETLQG |
1150:
VCGAALCENV | EGSFLCVCPN | SPEEFDPMTG | RCVPPRTSAG | TFPGSQPQAP |
1200:
ASPVLPARPP | PPPLPRRPST | PRQGPVGSGR | RECYFDTAAP | DACDNILARN |
1250:
VTWQECCCTV | GEGWGSGCRI | QQCPGTETAE | YQSLCPHGRG | YLAPSGDLSL |
1300:
RRDVDECQLF | RDQVCKSGVC | VNTAPGYSCY | CSNGYYYHTQ | RLECIDNDEC |
1350:
ADEEPACEGG | RCVNTVGSYH | CTCEPPLVLD | GSQRRCVSNE | SQSLDDNLGV |
1400:
CWQEVGADLV | CSHPRLDRQA | TYTECCCLYG | EAWGMDCALC | PAQDSDDFEA |
1450:
LCNVLRPPAY | SPPRPGGFGL | PYEYGPDLGP | PYQGLPYGPE | LYPPPALPYD |
1500:
PYPPPPGPFA | RREAPYGAPR | FDMPDFEDDG | GPYGESEAPA | PPGPGTRWPY |
1550:
RSRDTRRSFP | EPEEPPEGGS | YAGSLAEPYE | ELEAEECGIL | DGCTNGRCVR |
1600:
VPEGFTCRCF | DGYRLDMTRM | ACVDINECDE | AEAASPLCVN | ARCLNTDGSF |
1624:
RCICRPGFAP | THQPHHCAPA | RPRA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human LTBP-4
ELISA Kit for Human LTBP-4
CLIA Kit for Human LTBP-4
CLIA Kit for Human LTBP-4
Polyclonal Antibody for Human LTBP-4
Polyclonal Antibody for Human LTBP-4
Monoclonal Antibody for Human LTBP-4
Monoclonal Antibody for Human LTBP-4
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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Recovery
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Linearity
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);TISSUE SPECIFICITY;VARIANT MET-1141
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);SUBCELLULAR LOCATION;ALTERNATIVE SPLICING;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;INTERACTION WITH LTBP1 AND TGFB1;VARIANTS ILE-194; ALA-787; ALA-820 AND MET-1141
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
tissue :
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : VARIANT URDS GLY-311