Mapre1 CLIA Kit for Mouse(Mus musculus) | EIAab.comMapre1 CLIA Kit for Mouse(Mus musculus)

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Index > Protein center > Mapre1(Gene name) > Mouse

Mapre1 (Gene name),

Microtubule-associated protein RP/EB family member 1 (Protein name ), MARE1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mapre1;

Protein name:

Microtubule-associated protein RP/EB family member 1;

Alternative:

End-binding protein 1(EB1);APC-binding protein EB1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer. Interacts with DCTN1, DCTN2, DIAPH1, DIAPH2, TERF1 and dynein intermediate chain. Interacts with APC (via C-terminal domain), CLASP2, DST, KIF2C and STIM1; probably required for their targeting to the growing microtubule plus ends. Interacts with MTUS2; interaction is direct and probably targets MTUS2 to microtubules. Interacts with APC2. Interacts with CLASP1 (By similarity). According to PubMed:19553473, MAPRE1 does not interact with CDK5RAP2. Interacts with MACF1.

Function:

May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes (By similarity). May play a role in cell migration.

Subcellular Location:

Cytoplasm Cytoplasm cytoskeleton Cytoplasm cytoskeleton centrosome Associated with the microtubule network at the growing distal tip of microtubules. Also enriched at the centrosome.

Protein Attributes:

Sequence length:

268

Sequence:

50:

100:

150:

200:

250:

268:

EGFVIPDEGG | PQEEQEEY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:13589

SMR:

Q61166

UniGene:

Mm.143877

Pfam:

PF00307

String:

Q61166

Uniprot:

Q61166

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ELISA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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E2190m

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ELISA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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E2190r

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ELISA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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E2190c

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ELISA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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E2190h

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ELISA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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E2190b

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CLIA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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U2190m

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CLIA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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U2190r

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CLIA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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U2190c

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CLIA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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U2190b

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CLIA Kit for Mouse Microtubule-associated protein RP/EB family member 1

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U2190h

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Polyclonal Antibody for Mouse Microtubule-associated protein RP/EB family member 1

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P2190Rb-r

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Polyclonal Antibody for Mouse Microtubule-associated protein RP/EB family member 1

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P2190Rb-m

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Polyclonal Antibody for Mouse Microtubule-associated protein RP/EB family member 1

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P2190Rb-h

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Monoclonal Antibody for Mouse Microtubule-associated protein RP/EB family member 1

Protein for Mouse Microtubule-associated protein RP/EB family member 1

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

Sparks A.B. , Kay B.K.
Submitted (1996-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
3.

Bienvenut W.V. , Serrels B. , Brunton V.G. , Frame M.C.
Submitted (2008-02) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-17; 77-84; 114-150 AND 205-214;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Embryonic fibroblast.
4.

"EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration."
Wen Y. , Eng C.H. , Schmoranzer J. , Cabrera-Poch N. , Morris E.J.S. , Chen M. , Wallar B.J. , Alberts A.S. , Gundersen G.G.
Nat. Cell Biol.6:820-830(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH APC; DCTN1; DIAPH1 AND DIAPH2;MUTAGENESIS OF 211-GLU--GLU-213; 211-GLU--ASP-215 AND 220-LYS--ARG-222;FUNCTION
5.

"ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity."
Wu X. , Kodama A. , Fuchs E.
Cell135:137-148(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH MACF1
6.

"Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics."
Fong K.W. , Hau S.Y. , Kho Y.S. , Jia Y. , He L. , Qi R.Z.
Mol. Biol. Cell20:3660-3670(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
7.

"SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase."
van der Vaart B. , Manatschal C. , Grigoriev I. , Olieric V. , Gouveia S.M. , Bjelic S. , Demmers J. , Vorobjev I. , Hoogenraad C.C. , Steinmetz M.O. , Akhmanova A.
J. Cell Biol.193:1083-1099(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SLAIN2
8.

"RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly."
Lo J.C. , Jamsai D. , O'Connor A.E. , Borg C. , Clark B.J. , Whisstock J.C. , Field M.C. , Adams V. , Ishikawa T. , Aitken R.J. , Whittle B. , Goodnow C.C. , Ormandy C.J. , O'Bryan M.K.
PLoS Genet.8:E1002969-E1002969(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RABL2;TISSUE SPECIFICITY
9.

"Solution structure of the CH domain from mouse EB-1."
RIKEN structural genomics initiative (RSGI)
Submitted (2004-05) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 12-117

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