Gene name:
Mapk14 (Csbp1;Csbp2) ;
Protein name:
Mitogen-activated protein kinase 14 (MAP kinase 14;MAPK 14) ;
Alternative:
Mitogen-activated protein kinase p38 alpha (MAP kinase p38 alpha) ;CRK1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Binds to a kinase interaction motif within the protein tyrosine phosphatase, PTPRR. This interaction retains MAPK14 in the cytoplasm and prevents nuclear accumulation. Interacts with FAM48A, SPAG9 and NP60.
Function:
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO during hypoxic stress.
Subcellular Location:
Cytoplasm
Nucleus
Protein Attributes:
50:
MSQERPTFYR | QELNKTVWEV | PERYQNLSPV | GSGAYGSVCA | AFDTKTGHRV |
100:
AVKKLSRPFQ | SIIHAKRTYR | ELRLLKHMKH | ENVIGLLDVF | TPARSLEEFN |
150:
DVYLVTHLMG | ADLNNIVKCQ | KLTDDHVQFL | IYQILRGLKY | IHSADIIHRD |
200:
LKPSNLAVNE | DCELKILDFG | LARHTDDEMT | GYVATRWYRA | PEIMLNWMHY |
250:
NQTVDIWSVG | CIMAELLTGR | TLFPGTDHID | QLKLILRLVG | TPGAELLKKI |
300:
SSESARNYIQ | SLAQMPKMNF | ANVFIGANPL | AVDLLEKMLV | LDSDKRITAA |
350:
QALAHAYFAQ | YHDPDDEPVA | EPYDQSFESR | DFLIDEWKSL | TYDEVISFVP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Dog
Mouse
Rat
ELISA Kit for Rat MAP kinase 14
ELISA Kit for Rat MAP kinase 14
ELISA Kit for Rat MAP kinase 14
ELISA Kit for Rat MAP kinase 14
CLIA Kit for Rat MAP kinase 14
CLIA Kit for Rat MAP kinase 14
CLIA Kit for Rat MAP kinase 14
CLIA Kit for Rat MAP kinase 14
Polyclonal Antibody for Rat MAP kinase 14
Polyclonal Antibody for Rat MAP kinase 14
Polyclonal Antibody for Rat MAP kinase 14
Polyclonal Antibody for Rat MAP kinase 14
Monoclonal Antibody for Rat MAP kinase 14
Monoclonal Antibody for Rat MAP kinase 14
Monoclonal Antibody for Rat MAP kinase 14
Monoclonal Antibody for Rat MAP kinase 14
Protein for Rat MAP kinase 14
Protein for Rat MAP kinase 14
Protein for Rat MAP kinase 14
Protein for Rat MAP kinase 14
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain :
Lewis .
tissue :
Kidney .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON FUNCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON ENZYME REGULATION;REVIEW ON FUNCTION