NR1D1 CLIA Kit for Human(Homo sapiens) | EIAab.comNR1D1 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > NR1D1(Gene name) > Human

NR1D1 (Gene name),

Nuclear receptor subfamily 1 group D member 1 (Protein name ), NR1D1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

NR1D1(EAR1;HREV;THRAL);

Protein name:

Nuclear receptor subfamily 1 group D member 1;

Alternative:

V-erbA-related protein 1(EAR-1);Rev-erbA-alpha;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with C1D and NR2E3.

Function:

Functions as a constitutive transcriptional repressor. Possible receptor for triiodothyronine.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

614

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

614:

MHSEKLLSFR | VDAQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:9572

Pfam:

PF00104

String:

P20393

STRING:

9606.ENSP00000246672

MIM:

602408

SMR:

P20393

UniGene:

Hs.592130

Uniprot:

P20393

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ELISA Kit for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

E10637h

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Manual:

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96T

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ELISA Kit for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

E10637b

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Packing:

96T

ELISA Kit for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

E10637r

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96T

ELISA Kit for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

E10637m

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96T

CLIA Kit for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

U10637h

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MSDS:

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Packing:

96T

CLIA Kit for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

U10637m

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MSDS:

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Packing:

96T

CLIA Kit for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

U10637b

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MSDS:

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Packing:

96T

CLIA Kit for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

U10637r

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96T

Polyclonal Antibody for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

P10637Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

P10637Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Nuclear receptor subfamily 1 group D member 1

Cat.:

P10637Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Nuclear receptor subfamily 1 group D member 1

Protein for Human Nuclear receptor subfamily 1 group D member 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus."
Miyajima N. , Horiuchi R. , Shibuya Y. , Fukushige S. , Matsubara K. , Toyoshima K. , Yamamoto T.
Cell57:31-39(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
tissue: Placenta.
2.

"Isolation of a cDNA encoding human Rev-ErbA alpha: transcription from the noncoding DNA strand of a thyroid hormone receptor gene results in a related protein that does not bind thyroid hormone."
Lazar M.A. , Jones K.E. , Chin W.W.
DNA Cell Biol.9:77-83(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
tissue: Fetal skeletal muscle.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: PNS.
4.

"Genomic organization of the human thyroid hormone receptor alpha (c-erbA-1) gene."
Laudet V. , Begue A. , Henry C. , Joubel A. , Martin P. , Stehelin D. , Saule S.
Nucleic Acids Res.19:1105-1112(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 549-614
5.

"Orphan nuclear hormone receptor Rev-erbalpha regulates the human apolipoprotein CIII promoter."
Coste H. , Rodriguez J.C.
J. Biol. Chem.277:27120-27129(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene."
Yin L. , Lazar M.A.
Mol. Endocrinol.19:1452-1459(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
7.

"The orphan nuclear receptor Rev-erb alpha regulates circadian expression of plasminogen activator inhibitor type 1."
Wang J. , Yin L. , Lazar M.A.
J. Biol. Chem.281:33842-33848(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock."
Yin L. , Wang J. , Klein P.S. , Lazar M.A.
Science311:1002-1005(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-55 AND SER-59;UBIQUITINATION
9.

"A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription."
Wang J. , Li Y. , Zhang M. , Liu Z. , Wu C. , Yuan H. , Li Y.Y. , Zhao X. , Lu H.
FEBS J.274:5370-5381(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZNHIT1
10.

"Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways."
Yin L. , Wu N. , Curtin J.C. , Qatanani M. , Szwergold N.R. , Reid R.A. , Waitt G.M. , Parks D.J. , Pearce K.H. , Wisely G.B. , Lazar M.A.
Science318:1786-1789(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;HEME-BINDING
11.

"Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbalpha."
Wu N. , Yin L. , Hanniman E.A. , Joshi S. , Lazar M.A.
Genes Dev.23:2201-2209(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
12.

"Nuclear receptor Rev-erbalpha: a heme receptor that coordinates circadian rhythm and metabolism."
Yin L. , Wu N. , Lazar M.A.
Nucl. Recept. Signal.8:E001-E001(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
13.

"A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbalpha."
Valnegri P. , Khelfaoui M. , Dorseuil O. , Bassani S. , Lagneaux C. , Gianfelice A. , Benfante R. , Chelly J. , Billuart P. , Sala C. , Passafaro M.
Nat. Neurosci.14:1293-1301(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH OPHN1
14.

"Cryptochromes mediate rhythmic repression of the glucocorticoid receptor."
Lamia K.A. , Papp S.J. , Yu R.T. , Barish G.D. , Uhlenhaut N.H. , Jonker J.W. , Downes M. , Evans R.M.
Nature480:552-556(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CRY1 AND PER2
15.

"Direct regulation of CLOCK expression by REV-ERB."
Crumbley C. , Burris T.P.
PLoS ONE6:E17290-E17290(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
16.

"REV-ERBs: more than the sum of the individual parts."
Stratmann M. , Schibler U.
Cell Metab.15:791-793(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
17.

"REV-ERB-erating nuclear receptor functions in circadian metabolism and physiology."
Ripperger J.A. , Albrecht U.
Cell Res.22:1319-1321(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
18.

"The nuclear receptor REV-ERBalpha mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines."
Gibbs J.E. , Blaikley J. , Beesley S. , Matthews L. , Simpson K.D. , Boyce S.H. , Farrow S.N. , Else K.J. , Singh D. , Ray D.W. , Loudon A.S.
Proc. Natl. Acad. Sci. U.S.A.109:582-587(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
19.

"DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbalpha."
Chini C.C. , Escande C. , Nin V. , Chini E.N.
Biochem. J.451:453-461(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CCAR2;PHOSPHORYLATION AT SER-55 AND SER-59;UBIQUITINATION
20.

"Structural elements of an orphan nuclear receptor-DNA complex."
Zhao Q. , Khorasanizadeh S. , Miyoshi Y. , Lazar M.A. , Rastinejad F.
Mol. Cell1:849-861(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 123-215

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