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Index > Protein center > PPARA(Gene name) > Dog
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  • PPARA (Gene name),
  • Peroxisome proliferator-activated receptor alpha (Protein name ),  PPARA_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    PPARA(NR1C1);
    Protein name:
    Peroxisome proliferator-activated receptor alpha(PPAR-alpha);
    Alternative:
    Nuclear receptor subfamily 1 group C member 1;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Heterodimer; with RXRA. This heterodimerization is required for DNA binding and transactivation activity (By similarity). Interacts with AKAP13, LPIN1 and PRDM16. Also interacts with PPARBP coactivator in vitro Interacts with NCOA3 and NCOA6 coactivators. Interacts with CITED2; the interaction stimulates its transcriptional activity.
    Function:
    Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    468
    Sequence:
    50:
    MVDTESPICP | LSPLEADDLE | SPLSEEFLQE | MGNIQEISQS | IGEDSSGSFS | 
    100:
    FTEYQYLGSG | PGSDGSVITD | TLSPAPSPSS | VTHPAAPGGA | EEPSSVALNI | 
    150:
    ECRICGDRAS | GYHYGVHACE | GCKGFFRRTI | RLKLAYDKCD | RSCKIQKKNR | 
    200:
    NKCQYCRFHK | CLSVGMSHNA | IRFGRMPRSE | KAKLKAEILT | CEQDPEDAET | 
    250:
    ADLKSLAKRI | YEAYLKNFNM | NKVKARVILA | GKASNNPPFV | IHDMETLCMA | 
    300:
    EKTLVAKLVA | NGIQNKEAEV | RIFHCCQCTS | VETVTELTEF | AKSIPGFANL | 
    350:
    DLNDQVTLLK | YGVYEAIFAM | LSSVMNKDGM | LVAYGNGFIT | REFLKSLRKP | 
    400:
    FCDIMEPKFD | FAMKFNALEL | DDSDISLFVA | AIICCGDRPG | LLNVGHIEKM | 
    450:
    QEGIVHVLKL | HLQTNHPDNI | FLFPKLLQKM | ADLRQLVTEH | AQLVQVIKKT | 
    468:
    ESDAALHPLL | QEIYRDMY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Dog PPAR-alpha
    Cat.:
    E0934m
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Dog PPAR-alpha
    Cat.:
    E0934d
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Dog PPAR-alpha
    Cat.:
    E0934h
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    Packing:
    96T
    Range:
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    ELISA Kit for Dog PPAR-alpha
    Cat.:
    E0934r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog PPAR-alpha
    Cat.:
    U0934h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog PPAR-alpha
    Cat.:
    U0934r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog PPAR-alpha
    Cat.:
    U0934d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog PPAR-alpha
    Cat.:
    U0934m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Dog PPAR-alpha
    Polyclonal Antibody for Dog PPAR-alpha
    Cat.:
    P0934Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog PPAR-alpha
    Cat.:
    P0934Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog PPAR-alpha
    Cat.:
    P0934Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Dog PPAR-alpha
    Monoclonal Antibody for Dog PPAR-alpha
    Monoclonal Antibody for Dog PPAR-alpha
    Monoclonal Antibody for Dog PPAR-alpha
    Protein for Dog PPAR-alpha
    Protein for Dog PPAR-alpha
    Protein for Dog PPAR-alpha
    Protein for Dog PPAR-alpha

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    References
    1. 1.
      "Dog PPAR alpha cDNA sequence."
      Nagasawa M. , Ide T. , Murakami K.
      Submitted (2001-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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