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Index > Protein center > Ppif(Gene name) > Mouse
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  • Ppif (Gene name),
  • Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Protein name ),  PPIF_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ppif;
    Protein name:
    Peptidyl-prolyl cis-trans isomerase F, mitochondrial(PPIase F);
    Alternative:
    Rotamase F;Cyclophilin F(CyP-D);Rotamase F;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
    Subcellular Location:
    Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    206
    Sequence:
    50:
    MLALRCGPRL | LGLLSGPRSA | PLLLSATRTC | SDGGARGANS | SSGNPLVYLD | 
    100:
    VGADGQPLGR | VVLELKADVV | PKTAENFRAL | CTGEKGFGYK | GSTFHRVIPA | 
    150:
    FMCQAGDFTN | HNGTGGRSIY | GSRFPDENFT | LKHVGPGVLS | MANAGPNTNG | 
    200:
    SQFFICTIKT | DWLDGKHVVF | GHVKEGMDVV | KKIESFGSKS | GKTSKKIVIT | 
    206:
    DCGQLS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse PPIase F
    Cat.:
    E9275m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse PPIase F
    Cat.:
    E9275h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse PPIase F
    Cat.:
    E9275b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse PPIase F
    Cat.:
    E9275r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse PPIase F
    Cat.:
    U9275m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse PPIase F
    Cat.:
    U9275h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse PPIase F
    Cat.:
    U9275b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse PPIase F
    Cat.:
    U9275r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse PPIase F
    Cat.:
    P9275Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse PPIase F
    Cat.:
    P9275Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse PPIase F
    Polyclonal Antibody for Mouse PPIase F
    Cat.:
    P9275Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse PPIase F
    Monoclonal Antibody for Mouse PPIase F
    Monoclonal Antibody for Mouse PPIase F
    Monoclonal Antibody for Mouse PPIase F
    Protein for Mouse PPIase F
    Protein for Mouse PPIase F
    Protein for Mouse PPIase F
    Protein for Mouse PPIase F

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    Linearity
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    References
    1. 1.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary tumor.
    2. 2.
      "Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death."
      Nakagawa T. , Shimizu S. , Watanabe T. , Yamaguchi O. , Otsu K. , Yamagata H. , Inohara H. , Kubo T. , Tsujimoto Y.
      Nature434:652-658(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    3. 3.
      "Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death."
      Baines C.P. , Kaiser R.A. , Purcell N.H. , Blair N.S. , Osinska H. , Hambleton M.A. , Brunskill E.W. , Sayen M.R. , Gottlieb R.A. , Dorn G.W. , Robbins J. , Molkentin J.D.
      Nature434:658-662(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    4. 4.
      "Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia."
      Schinzel A.C. , Takeuchi O. , Huang Z. , Fisher J.K. , Zhou Z. , Rubens J. , Hetz C. , Danial N.N. , Moskowitz M.A. , Korsmeyer S.J.
      Proc. Natl. Acad. Sci. U.S.A.102:12005-12010(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    5. 5.
      "Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation."
      Basso E. , Petronilli V. , Forte M.A. , Bernardi P.
      J. Biol. Chem.283:26307-26311(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    6. 6.
      "Cyclophilin D modulates mitochondrial F0F1-ATP synthase by interacting with the lateral stalk of the complex."
      Giorgio V. , Bisetto E. , Soriano M.E. , Dabbeni-Sala F. , Basso E. , Petronilli V. , Forte M.A. , Bernardi P. , Lippe G.
      J. Biol. Chem.284:33982-33988(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy."
      Hafner A.V. , Dai J. , Gomes A.P. , Xiao C.Y. , Palmeira C.M. , Rosenzweig A. , Sinclair D.A.
      Aging (Albany NY)2:914-923(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-166;INTERACTION WITH SIRT3
    8. 8.
      "Complement 1q-binding protein inhibits the mitochondrial permeability transition pore and protects against oxidative stress-induced death."
      McGee A.M. , Baines C.P.
      Biochem. J.433:119-125(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH C1QBP
    9. 9.
      "Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels."
      Chinopoulos C. , Konrad C. , Kiss G. , Metelkin E. , Torocsik B. , Zhang S.F. , Starkov A.A.
      FEBS J.278:1112-1125(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ATP5B
    10. 10.
      "Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore."
      Nguyen T.T. , Stevens M.V. , Kohr M. , Steenbergen C. , Sack M.N. , Murphy E.
      J. Biol. Chem.286:40184-40192(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: S-NITROSYLATION AT CYS-202
    11. 11.
      "p53 opens the mitochondrial permeability transition pore to trigger necrosis."
      Vaseva A.V. , Marchenko N.D. , Ji K. , Tsirka S.E. , Holzmann S. , Moll U.M.
      Cell149:1536-1548(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TP53
    12. 12.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-66; LYS-85; LYS-174 AND LYS-189;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    13. 13.
      "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J. , Newman J.C. , Held J.M. , Cusack M.P. , Sorensen D.J. , Li B. , Schilling B. , Mooney S.D. , Kahn C.R. , Verdin E. , Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-66;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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