Gene name:
Scn9a (Kiaa4197) ;
Protein name:
Sodium channel protein type 9 subunit alpha ;
Alternative:
Sodium channel protein type IX subunit alpha ;Peripheral sodium channel 1 (PN1) ;Voltage-gated sodium channel subunit alpha Nav1.7 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with NEDD4 and NEDD4L.
Function:
Plays a role in pain mechanisms, especially in the development of inflammatory pain.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MAMLPPPGPQ | SFVHFTKQSL | ALIEQRISEE | KAKGHKDEKK | DDEEEGPKPS |
100:
SDLEAGKQLP | FIYGDIPPGM | VSEPLEDLDP | YYADKKTFIV | LNKGKAIFRF |
150:
NATPALYMLS | PFSPLRRISI | KILVHSLFSM | LIMCTILTNC | IFMTMSNPPD |
200:
WTKNVEYTFT | GIYTFESLIK | ILARGFCVGE | FTFLRDPWNW | LDFVVIVFAY |
250:
LTEFVNLGNV | SALRTFRVLR | ALKTISVIPG | LKTIVGALIQ | SVKKLSDVMI |
300:
LTVFCLSVFA | LIGLQLFMGN | LKHKCFRKDL | EQNETLESIM | STAESEEELK |
350:
RYFYYLEGSK | DALLCGFSTD | SGQCPEGYEC | VTAGRNPDYG | YTSFDTFGWA |
400:
FLALFRLMTQ | DYWENLYQQT | LRAAGKTYMI | FFVVVIFLGS | FYLINLILAV |
450:
VAMAYEEQNQ | ANIEEAKQKE | LEFQQMLDRL | KKEQEEAEAI | AAAAAEYTSL |
500:
GRSRIMGLSE | SSSETSRLSS | KSAKERRNRR | KKKKQKLSSG | EEKGDDEKLS |
550:
KSGSEESIRK | KSFHLGVEGH | HRAREKRLST | PNQSPLSIRG | SLFSARRSSR |
600:
TSLFSFKGRG | RDLGSETEFA | DDEHSIFGDN | ESRRGSLFVP | HRPRERRSSN |
650:
ISQASRSPPV | LPVNGKMHSA | VDCNGVVSLV | DGPSALMLPN | GQLLPEVIID |
700:
KATSDDSGTT | NQMRKKRLSS | SYFLSEDMLN | DPHLRQRAMS | RASILTNTVE |
750:
ELEESRQKCP | PWWYRFAHTF | LIWNCSPYWI | KFKKFIYFIV | MDPFVDLAIT |
800:
ICIVLNTLFM | AMEHHPMTDE | FKNVLAVGNL | VFTGIFAAEM | VLKLIAMDPY |
850:
EYFQVGWNIF | DSLIVTLSLV | ELFLADVEGL | SVLRSFRLLR | VFKLAKSWPT |
900:
LNMLIKIIGN | SVGALGNLTL | VLAIIVFIFA | VVGMQLFGKS | YKECVCKINE |
950:
NCKLPRWHMN | DFFHSFLIVF | RVLCGEWIET | MWDCMEVAGQ | TMCLIVYMMV |
1000:
MVIGNLVVLN | LFLALLLSSF | SSDNLTAIEE | DTDANNLQIA | VARIKRGINY |
1050:
VKQTLREFIL | KSFSKKPKGS | KDTKRTADPN | NKRENYISNR | TLAEISKDHN |
1100:
FLKEKDKISG | FSSSLDKSFM | DENDYQSFIH | NPSLTVTVPI | APGESDLENM |
1150:
NTEELSSDSD | SDYSKERRNR | SSSSECSTVD | NPLPGEEEAE | AEPINADEPE |
1200:
ACFTDGCVRR | FPCCQVNIDS | GKGKVWWTIR | KTCYRIVEHS | WFESFIVLMI |
1250:
LLSSGALAFE | DIYIEKKKTI | KIILEYADKI | FTYIFILEML | LKWVAYGYKT |
1300:
YFTNAWCWLD | FLIVDVSLVT | LVANTLGYSD | LGPIKSLRTL | RALRPLRALS |
1350:
RFEGMRVVVN | ALIGAIPSIM | NVLLVCLIFW | LIFSIMGVNL | FAGKFYECVN |
1400:
TTDGSRFSVS | QVANRSECFA | LMNVSGNVRW | KNLKVNFDNV | GLGYLSLLQV |
1450:
ATFKGWMDIM | YAAVDSVNVN | AQPIYEYNLY | MYIYFVIFII | FGSFFTLNLF |
1500:
IGVIIDNFNQ | QKKKLGGQDI | FMTEEQKKYY | NAMKKLGSKK | PQKPIPRPGN |
1550:
KFQGCIFDLV | TNQAFDITIM | VLICLNMVTM | MVEKEGQTDY | MSFVLYWINV |
1600:
VFIILFTGEC | VLKLISLRHY | YFTVGWNIFD | FVVVILSIVG | MFLAEMIEKY |
1650:
FVSPTLFRVI | RLARIGRILR | LIKGAKGIRT | LLFALMMSLP | ALFNIGLLLF |
1700:
LVMFIYAIFG | MSNFAYVKKE | AGINDMFNFE | TFGNSMICLF | QITTSAGWDG |
1750:
LLAPILNSAP | PDCDPKKVHP | GSSVEGDCGN | PSVGIFYFVS | YIIISFLVVV |
1800:
NMYIAVILEN | FSVATEESTE | PLSEDDFEMF | YEVWEKFDPD | ATQFIEFCKL |
1850:
SDFAAALDPP | LLIAKPNKVQ | LIAMDLPMVS | GDRIHCLDIL | FAFTKRVLGE |
1900:
SGEMDSLRSQ | MEERFMSANP | SKVSYEPITT | TLKRKQEDVS | ATIIQRAYRR |
1950:
YRLRQNVKNI | SSIYIKDGDR | DDDLPNKEDI | VFDNVNENSS | PEKTDATAST |
1984:
ISPPSYDSVT | KPDQEKYETD | KTEKEDKEKD | ESRK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rabbit
Mouse
Rat
ELISA Kit for Mouse Sodium channel protein type 9 subunit alpha
ELISA Kit for Mouse Sodium channel protein type 9 subunit alpha
ELISA Kit for Mouse Sodium channel protein type 9 subunit alpha
ELISA Kit for Mouse Sodium channel protein type 9 subunit alpha
CLIA Kit for Mouse Sodium channel protein type 9 subunit alpha
CLIA Kit for Mouse Sodium channel protein type 9 subunit alpha
CLIA Kit for Mouse Sodium channel protein type 9 subunit alpha
CLIA Kit for Mouse Sodium channel protein type 9 subunit alpha
Polyclonal Antibody for Mouse Sodium channel protein type 9 subunit alpha
Polyclonal Antibody for Mouse Sodium channel protein type 9 subunit alpha
Polyclonal Antibody for Mouse Sodium channel protein type 9 subunit alpha
Polyclonal Antibody for Mouse Sodium channel protein type 9 subunit alpha
Monoclonal Antibody for Mouse Sodium channel protein type 9 subunit alpha
Monoclonal Antibody for Mouse Sodium channel protein type 9 subunit alpha
Monoclonal Antibody for Mouse Sodium channel protein type 9 subunit alpha
Monoclonal Antibody for Mouse Sodium channel protein type 9 subunit alpha
Protein for Mouse Sodium channel protein type 9 subunit alpha
Protein for Mouse Sodium channel protein type 9 subunit alpha
Protein for Mouse Sodium channel protein type 9 subunit alpha
Protein for Mouse Sodium channel protein type 9 subunit alpha
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
2.
"Mouse sodium channel 25 in m13mp19."
Jover E.
,
Shah V.
Submitted (1995-05) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1675-1983
tissue :
Brain .
3.
"Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N.
,
Kikuno R.F.
,
Ohara R.
,
Inamoto S.
,
Nagase T.
,
Ohara O.
,
Koga H.
Submitted (2005-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1740-1983
tissue :
Fetal brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NEDD4 AND NEDD4L;UBIQUITINATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN INFLAMMATORY PAIN