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Index > Protein center > SIGMAR1(Gene name) > Bovine
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  • SIGMAR1 (Gene name),
  • Sigma non-opioid intracellular receptor 1 (Protein name ),  SGMR1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SIGMAR1(OPRS1);
    Protein name:
    Sigma non-opioid intracellular receptor 1;
    Alternative:
    Sigma 1-type opioid receptor(Sigma1-receptor;Sigma1R);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Forms a ternary complex with ANK2 and ITPR3. The complex is disrupted by agonists. Interacts with KCNA4.
    Function:
    Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.
    Subcellular Location:
    Nucleus inner membrane Nucleus outer membrane Endoplasmic reticulum membrane Lipid droplet Cell junction Cell membrane Cell projection growth cone Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum. Enriched at cell-cell communication regions, growth cone and postsynaptic structures. Localization is modulated by ligand-binding.
    Protein Attributes:
    Sequence length:
    223
    Sequence:
    50:
    MCWAVGRRWA | WAALLLAVAA | VLAQVVWLWL | GTQSFVFQHE | EIAQLARQYA | 
    100:
    GLDHELAFSR | LIVELRRLHP | GHVLPDEDLQ | WVFVNAGGWM | GAMCLLHASL | 
    150:
    SEYVLLFGTA | LGSSGHSGRY | WAEISDTIIS | GTFHQWREGT | TKSEVFYPGE | 
    200:
    TVVHGPGEAT | AVEWGPNTWM | VEYGRGVIPS | TLGFALADTV | FSTQDFLTLF | 
    223:
    YTLRAYARGL | RLELTTYLFG | QDA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    E5642h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    E5642r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    E5642b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    E5642c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    E5642m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    U5642r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    U5642h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    U5642m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    U5642c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    U5642b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Polyclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Polyclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    P5642Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    P5642Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Cat.:
    P5642Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Monoclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Monoclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Monoclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Monoclonal Antibody for Bovine Sigma non-opioid intracellular receptor 1
    Protein for Bovine Sigma non-opioid intracellular receptor 1
    Protein for Bovine Sigma non-opioid intracellular receptor 1
    Protein for Bovine Sigma non-opioid intracellular receptor 1
    Protein for Bovine Sigma non-opioid intracellular receptor 1
    Protein for Bovine Sigma non-opioid intracellular receptor 1

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    References
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