Trim63 CLIA Kit for Rat(Rattus norvegicus) | EIAab.comTrim63 CLIA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Trim63(Gene name) > Rat

Trim63 (Gene name),

E3 ubiquitin-protein ligase TRIM63 (Protein name ), TRI63_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Trim63(Murf1);

Protein name:

E3 ubiquitin-protein ligase TRIM63;

Alternative:

Tripartite motif-containing protein 63;Muscle-specific RING finger protein 1(MuRF-1;MuRF1);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homooligomer and heterooligomer. Interacts with SUMO2, titin/TTN and GMEB1. Interacts with TRIM54 and probably with TRIM55 and TNNI3. Forms a ternary complex with GNB2L1 and PRKCE.

Function:

E3 ubiquitin ligase. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.

Subcellular Location:

Cytoplasm Nucleus Localizes to the M- and Z-lines in skeletal muscle. Colocalizes with TNNI3 in myocytes.

Protein Attributes:

Sequence length:

351

Sequence:

50:

100:

150:

200:

250:

300:

350:

351:

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

Q91Z63

UniGene:

Rn.40636

Pfam:

PF00643

String:

Q91Z63

KEGG:

rno:140939

STRING:

10116.ENSRNOP00000037509

Uniprot:

Q91Z63

FOR

ELISA Kit for Rat E3 ubiquitin-protein ligase TRIM63

Cat.:

E5054r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat E3 ubiquitin-protein ligase TRIM63

Cat.:

E5054m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Rat E3 ubiquitin-protein ligase TRIM63

Cat.:

E5054h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat E3 ubiquitin-protein ligase TRIM63

Cat.:

U5054r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat E3 ubiquitin-protein ligase TRIM63

Cat.:

U5054m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat E3 ubiquitin-protein ligase TRIM63

Cat.:

U5054h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rat E3 ubiquitin-protein ligase TRIM63

Cat.:

P5054Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat E3 ubiquitin-protein ligase TRIM63

Cat.:

P5054Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat E3 ubiquitin-protein ligase TRIM63

Cat.:

P5054Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Rat E3 ubiquitin-protein ligase TRIM63

Protein for Rat E3 ubiquitin-protein ligase TRIM63

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification of ubiquitin ligases required for skeletal muscle atrophy."
Bodine S.C. , Latres E. , Baumhueter S. , Lai V.K.-M. , Nunez L. , Clarke B.A. , Poueymirou W.T. , Panaro F.J. , Na E. , Dharmarajan K. , Pan Z.-Q. , Valenzuela D.M. , DeChiara T.M. , Stitt T.N. , Yancopoulos G.D. , Glass D.J.
Science294:1704-1708(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INDUCTION;FUNCTION
strain: Sprague-Dawley.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Prostate.
3.

"Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1."
McElhinny A.S. , Kakinuma K. , Sorimachi H. , Labeit S. , Gregorio C.C.
J. Cell Biol.157:125-136(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
4.

"Induction of MafBx and Murf ubiquitin ligase mRNAs in rat skeletal muscle after LPS injection."
Dehoux M.J.M. , van Beneden R.P. , Fernandez-Celemin L. , Lause P.L. , Thissen J.-P.M.
FEBS Lett.544:214-217(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
5.

"Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle."
Wray C.J. , Mammen J.M.V. , Hershko D.D. , Hasselgren P.-O.
Int. J. Biochem. Cell Biol.35:698-705(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
6.

"Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression."
Lecker S.H. , Jagoe R.T. , Gilbert A. , Gomes M. , Baracos V. , Bailey J. , Price S.R. , Mitch W.E. , Goldberg A.L.
FASEB J.18:39-51(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
7.

"Muscle ring finger protein-1 inhibits PKC-epsilon activation and prevents cardiomyocyte hypertrophy."
Arya R. , Kedar V. , Hwang J.R. , McDonough H. , Li H.-H. , Taylor J. , Patterson C.
J. Cell Biol.167:1147-1159(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"Indinavir alters regulators of protein anabolism and catabolism in skeletal muscle."
Hong-Brown L.Q. , Pruznak A.M. , Frost R.A. , Vary T.C. , Lang C.H.
Am. J. Physiol.289:E382-E390(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
9.

"Selective downregulation of ubiquitin conjugation cascade mRNA occurs in the senescent rat soleus muscle."
DeRuisseau K.C. , Kavazis A.N. , Powers S.K.
Exp. Gerontol.40:526-531(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION

Product Feedback Wall

* Email:
*Comments: