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Index > Protein center > UCN(Gene name) > Human
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  • UCN (Gene name),
  • Urocortin (Protein name ),  UCN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    UCN;
    Protein name:
    Urocortin;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CRHR1 and CRHR2 (via their N-terminal extracellular domain).
    Function:
    Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    124
    Sequence:
    50:
    MRQAGRAALL | AALLLLVQLC | PGSSQRSPEA | AGVQDPSLRW | SPGARNQGGG | 
    100:
    ARALLLLLAE | RFPRRAGPGR | LGLGTAGERP | RRDNPSLSID | LTFHLLRTLL | 
    124:
    ELARTQSQRE | RAEQNRIIFD | SVGK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    MIM:
    Pfam:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Urocortin
    Cat.:
    E2199m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Urocortin
    Cat.:
    E2199h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Urocortin
    Cat.:
    E2199r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Urocortin
    Cat.:
    U2199m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Urocortin
    Cat.:
    U2199h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Urocortin
    Cat.:
    U2199r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Urocortin
    Cat.:
    P2199Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Urocortin
    Cat.:
    P2199Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Urocortin
    Cat.:
    P2199Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Urocortin
    Monoclonal Antibody for Human Urocortin
    Monoclonal Antibody for Human Urocortin
    Protein for Human Urocortin
    Protein for Human Urocortin
    Protein for Human Urocortin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION
      tissue: Placenta.
    2. 2.
      "The structures of the mouse and human urocortin genes (Ucn and UCN)."
      Zhao L. , Donaldson C.J. , Smith G.W. , Vale W.W.
      Genomics50:23-33(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;IDENTIFICATION BY MASS SPECTROMETRY
    7. 7.
      "Urocortin 1 in colonic mucosa in patients with ulcerative colitis."
      Saruta M. , Takahashi K. , Suzuki T. , Torii A. , Kawakami M. , Sasano H.
      J. Clin. Endocrinol. Metab.89:5352-5361(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;ASSOCIATION WITH INFLAMMATION IN ULCERATIVE COLITIS
    8. 8.
      "Common and divergent structural features of a series of corticotropin releasing factor-related peptides."
      Grace C.R.R. , Perrin M.H. , Cantle J.P. , Vale W.W. , Rivier J.E. , Riek R.
      J. Am. Chem. Soc.129:16102-16114(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 83-122
    9. 9.
      "Structural basis for hormone recognition by the Human CRFR2{alpha} G protein-coupled receptor."
      Pal K. , Swaminathan K. , Xu H.E. , Pioszak A.A.
      J. Biol. Chem.285:40351-40361(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.75 ANGSTROMS) OF 107-122 IN COMPLEX WITH CRHR2;MUTAGENESIS OF ARG-116; ILE-118; PHE-119 AND VAL-122;INTERACTION WITH CRHR2 AND CRHR1
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