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Index > Protein center > VASP(Gene name) > Dog
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  • VASP (Gene name),
  • Vasodilator-stimulated phosphoprotein (Protein name ),  VASP_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VASP;
    Protein name:
    Vasodilator-stimulated phosphoprotein(VASP);
    Alternative:

    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Homotetramer. Interacts with PFN1, PFN2, LPP, ACTN1 and ACTG1. Interacts, via the EVH1 domain, with the Pro-rich regions of ZYX. This interaction is important for targeting to focal adhesions and the formation of actin-rich structures at the apical surface of cells. Interacts, via the EVH1 domain, with the Pro-rich domain of Listeria monocytogenes actA. Interacts with APBB1IP. Interacts, via the Pro-rich domain, with the C-terminal SH3 domain of DNMBP.
    Function:
    Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
    Subcellular Location:
    Cytoplasm Cytoplasm cytoskeleton Cell junction focal adhesion Cell projection lamellipodium membrane Cell projection filopodium membrane Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members. Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions.
    Protein Attributes:
    Sequence length:
    384
    Sequence:
    50:
    MSETVICSSW | ATVMLYDDSN | KRWLPAGTGP | QSFSRVQIYH | NPTANSFRVV | 
    100:
    GWKMQPDQQV | VINCAIVRGI | KYNQATPTFH | QWRDARQVWG | LNFGSKEDAT | 
    150:
    QFAAAMASAL | EALEGGGPPP | PPPPAAPPTW | SVQNGPASEE | VEQQKRQQPG | 
    200:
    PPEHLERRVS | NAGGPPAPPA | GGPPPPPGPP | PPPGPPPPPG | VSLSGGSAAG | 
    250:
    HGAGGGPPPA | PPLPTAQGTS | GGGTGAPGLA | AAIAGAKLRK | VSKQEEASGG | 
    300:
    PPVPKAESTR | STGGGLMEEM | NAMLARRRKA | TQVGEKPPKD | ESANEEPEAR | 
    350:
    VPVPAQSETV | RRPWEKNSTT | LPRMKSSSSV | TTSEAHPSTP | SSSDESDLER | 
    384:
    VKQELLEEVR | KELQKVKEEI | IEAFVQELRK | RGSP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Dog VASP
    Cat.:
    E9578h
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    Packing:
    96T
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    ELISA Kit for Dog VASP
    MSDS:
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    ELISA Kit for Dog VASP
    Cat.:
    E9578b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Dog VASP
    Cat.:
    E9578m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Dog VASP
    MSDS:
    Please sign in first.
    CLIA Kit for Dog VASP
    Cat.:
    U9578h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Dog VASP
    Cat.:
    U9578b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog VASP
    Cat.:
    U9578m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Dog VASP
    Cat.:
    P9578Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog VASP
    Cat.:
    P9578Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog VASP
    Polyclonal Antibody for Dog VASP
    Monoclonal Antibody for Dog VASP
    Monoclonal Antibody for Dog VASP
    Monoclonal Antibody for Dog VASP
    Monoclonal Antibody for Dog VASP
    Protein for Dog VASP
    Protein for Dog VASP
    Protein for Dog VASP
    Protein for Dog VASP

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    References
    1. 1.
      "Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP."
      Haffner C. , Jarchau T. , Reinhard M. , Hoppe J. , Lohmann S.M. , Walter U.
      EMBO J.14:19-27(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Cocker spaniel.
      tissue: Kidney.
    2. 2.
      "Rab13 regulates PKA signaling during tight junction assembly."
      Koehler K. , Louvard D. , Zahraoui A.
      J. Cell Biol.165:175-180(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PHOSPHORYLATION AT SER-160 BY PKA
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