Protein name:
V-set domain-containing T-cell activation inhibitor 1 ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Subcellular Location:
Cell membrane
Lipid-anchor
GPI-anchor
Expressed at the cell surface. A soluble form has also been detected.
Protein Attributes:
50:
MASLGQIIFW | SIINVIIILA | GAIVLIIGFG | ISGKHFITVT | TFTSAGNIGE |
100:
DGTLSCTFEP | DIKLNGIVIQ | WLKEGIKGLV | HEFKEGKDDL | SQQHEMFRGR |
150:
TAVFADQVVV | GNASLRLKNV | QLTDAGTYTC | YIHTSKGKGN | ANLEYKTGAF |
200:
SMPEINVDYN | ASSESLRCEA | PRWFPQPTVA | WASQVDQGAN | FSEVSNTSFE |
250:
LNSENVTMKV | VSVLYNVTIN | NTYSCMIEND | IAKATGDIKV | TDSEVKRRSQ |
282:
LELLNSGPSP | CVSSVSAAGW | ALLSLSCCLM | LR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Rat V-set domain-containing T-cell activation inhibitor 1
ELISA Kit for Rat V-set domain-containing T-cell activation inhibitor 1
ELISA Kit for Rat V-set domain-containing T-cell activation inhibitor 1
CLIA Kit for Rat V-set domain-containing T-cell activation inhibitor 1
CLIA Kit for Rat V-set domain-containing T-cell activation inhibitor 1
CLIA Kit for Rat V-set domain-containing T-cell activation inhibitor 1
Polyclonal Antibody for Rat V-set domain-containing T-cell activation inhibitor 1
Polyclonal Antibody for Rat V-set domain-containing T-cell activation inhibitor 1
Polyclonal Antibody for Rat V-set domain-containing T-cell activation inhibitor 1
Monoclonal Antibody for Rat V-set domain-containing T-cell activation inhibitor 1
Monoclonal Antibody for Rat V-set domain-containing T-cell activation inhibitor 1
Monoclonal Antibody for Rat V-set domain-containing T-cell activation inhibitor 1
Protein for Rat V-set domain-containing T-cell activation inhibitor 1
Protein for Rat V-set domain-containing T-cell activation inhibitor 1
Protein for Rat V-set domain-containing T-cell activation inhibitor 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Thymus .