CD300A ELISA Kit for Human(Homo sapiens) | EIAab.comCD300A ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CD300A(Gene name) > Human

CD300A (Gene name),

CMRF35-like molecule 8 (Protein name ), CLM8_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CD300A(HSPC083;CMRF35H;IGSF12);

Protein name:

CMRF35-like molecule 8(CLM-8);

Alternative:

CMRF-35-H9(CMRF35-H9);CD300 antigen-like family member A;IRC1/IRC2;CMRF35-H;Inhibitory receptor protein 60(IRp60);Immunoglobulin superfamily member 12(IgSF12);NK inhibitory receptor;

CD:

CD300a;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Upon tyrosine-phosphorylation, interacts with PTN6/SHP-1 and PTPN11/SHP-2 and INPP5D.

Function:

Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.

Subcellular Location:

Cell membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

299

Sequence:

50:

100:

150:

200:

250:

299:

VEVEYSTVAS | PREELHYASV | VFDSNTNRIA | AQRPREEEPD | SDYSVIRKT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:11314

Pfam:

PF07686

STRING:

9606.ENSP00000353259

MIM:

606790

UniGene:

Hs.9688

String:

Q9UGN4

SMR:

Q9UGN4

Uniprot:

Q9UGN4

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ELISA Kit for Human CLM-8

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E9365h

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96T

ELISA Kit for Human CLM-8

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E9365r

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96T

ELISA Kit for Human CLM-8

Cat.:

E9365m

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96T

CLIA Kit for Human CLM-8

Cat.:

U9365m

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96T

CLIA Kit for Human CLM-8

Cat.:

U9365r

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96T

CLIA Kit for Human CLM-8

Cat.:

U9365h

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96T

Polyclonal Antibody for Human CLM-8

Cat.:

P9365Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human CLM-8

Cat.:

P9365Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human CLM-8

Cat.:

P9365Rb-m

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40ug/0.2ml

Monoclonal Antibody for Human CLM-8

Protein for Human CLM-8

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells."
Cantoni C. , Bottino C. , Augugliaro R. , Morelli L. , Marcenaro E. , Castriconi R. , Vitale M. , Pende D. , Sivori S. , Millo R. , Biassoni R. , Moretta L. , Moretta A.
Eur. J. Immunol.29:3148-3159(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;PHOSPHORYLATION
tissue: Lymphoid tissue.
2.

"IRC1 isoforms."
Cantoni C. , Biassoni R.
Submitted (1998-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3);VARIANT GLN-111
tissue: Lymphoid tissue.
3.

"The CMRF-35 mAb recognizes a second leukocyte membrane molecule with a domain similar to the poly Ig receptor."
Green B.J. , Clark G.J. , Hart D.N.J.
Int. Immunol.10:891-899(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
4.

"The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17."
Clark G.J. , Green B.J. , Hart D.N.J.
Tissue Antigens55:101-109(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1);FUNCTION
5.

"Human partial CDS cloned from CD34+ stem cells."
Zhang Q.H. , Ye M. , Zhou J. , Shen Y. , Wu X.Y. , Guan Z.Q. , Wang L. , Fan H.Y. , Mao Y.F. , Dai M. , Huang Q.H. , Chen S.J. , Chen Z.
Submitted (1999-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
tissue: Umbilical cord blood.
6.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Blood.
8.

"The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells."
Bachelet I. , Munitz A. , Moretta A. , Moretta L. , Levi-Schaffer F.
J. Immunol.175:7989-7995(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION;TISSUE SPECIFICITY
9.

"The crystal structure of IRp60 ectodomain."
Dimasi N. , Marquez J.A.
Submitted (2007-06) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 19-128
10.

"Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility."
Speckman R.A. , Wright Daw J.A. , Helms C. , Duan S. , Cao L. , Taillon-Miller P. , Kwok P.Y. , Menter A. , Bowcock A.M.
Hum. Genet.112:34-41(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLN-111

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