Protein name:
UMP-CMP kinase 2, mitochondrial ;
Alternative:
2.7.4.6;Nucleoside-diphosphate kinase ) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs.
Subcellular Location:
Mitochondrion
Protein Attributes:
50:
MAFARRLLRG | PLSGPLLGRR | GVCAGAMAPP | RRFVLELPDC | TLAHFALGAD |
100:
APGDADAPDP | RLAALLGPPE | RSYSLCVPVT | PDAGCGARVR | AARLHQRLLH |
150:
QLRRGPFQRC | QLLRLLCYCP | GGQAGGAQQG | FLLRDPLDDP | DTRQALLELL |
200:
GACQEAPRPH | LGEFEADPRG | QLWQRLWEVQ | DGRRLQVGCA | QVVPVPEPPL |
250:
HPVVPDLPSS | VVFPDREAAR | AVLEECTSFI | PEARAVLDLV | DQCPKQIQKG |
300:
KFQVVAIEGL | DATGKTTVTQ | SVADSLKAVL | LKSPPSCIGQ | WRKIFDDEPT |
350:
IIRRAFYSLG | NYIVASEIAK | ESAKSPVIVD | RYWHSTATYA | IATEVSGGLQ |
400:
HLPPAHHPVY | QWPEDLLKPD | LILLLTVSPE | ERLQRLQGRG | MEKTREEAEL |
449:
EANSVFRQKV | EMSYQRMENP | GCHVVDASPS | REKVLQTVLS | LIQNSFSEP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human UMP-CMP kinase 2, mitochondrial
ELISA Kit for Human UMP-CMP kinase 2, mitochondrial
CLIA Kit for Human UMP-CMP kinase 2, mitochondrial
CLIA Kit for Human UMP-CMP kinase 2, mitochondrial
Polyclonal Antibody for Human UMP-CMP kinase 2, mitochondrial
Polyclonal Antibody for Human UMP-CMP kinase 2, mitochondrial
Monoclonal Antibody for Human UMP-CMP kinase 2, mitochondrial
Monoclonal Antibody for Human UMP-CMP kinase 2, mitochondrial
Protein for Human UMP-CMP kinase 2, mitochondrial
Protein for Human UMP-CMP kinase 2, mitochondrial
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
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Cited for NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
2.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
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more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Testis .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 9-449 (ISOFORM 1)
tissue :
Lymph . tissue :
Prostate .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for FUNCTION;CATALYTIC ACTIVITY
Vaild Sequence:
