Gene name:
Cmtr1 (Ftsjd2) ;
Protein name:
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 ;
Alternative:
Cap1 2'O-ribose methyltransferase 1 (MTr1) ;Cap methyltransferase 1 ;FtsJ methyltransferase domain-containing protein 2 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with POLR2A (via C-terminus).
Function:
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MKRRTDPECT | APLKKQKRIG | ELARHLSSTS | DDEPLSSVSH | AAKASTTSLS |
100:
GSDSETEGKQ | PCSDGFKDAF | KADSLVEGTS | SRYSMYNSVS | QKLMAKMGFR |
150:
EGEGLGKYSQ | GRKDIVETSN | QKGRRGLGLT | LQGFDQELNV | DWRDEPEPNA |
200:
CEQVSWFPEC | TTEIPDSREM | SDWMVVGKRK | MVIEDETEFC | GEELLHSMLK |
250:
CKSVFDILDG | EEMRRARTRA | NPYEMIRGVF | FLNRAAMKMA | NMDFVFDRMF |
300:
TNPLDSSGKP | LLKESDIDLL | YFADVCAGPG | GFSEYVLWRR | KWHAKGFGMT |
350:
LKGPNDFKLE | DFYSASSELF | EPYYGEGGVD | GDGDITRPEN | INAFRNFVLD |
400:
NTDRKGVHFV | MADGGFSVEG | QENLQEILSK | QLLLCQFLMA | LSVVRTGGHF |
450:
VCKTFDLFTP | FSVGLIYLLY | CCFERVCLFK | PVTSRPANSE | RYVVCKGLKV |
500:
GIDDVREYLF | SVNIQLNQLR | NTDSDVNLVV | PLSVIKGDHE | FNDYMIRSNE |
550:
SYCSLQIKAL | AKIHAFVQDT | TLSEPRQAEI | RKECLQLWEI | PDRARVAPSP |
600:
SDPKFKFFEL | IKDTDINIFS | YKPTLLTAKT | LEKIRPVLEY | RCMVSGSEQK |
650:
FLLGLGKSQI | YTWDGRQSDR | WVKLDLKTEL | PRDTLLCVEI | VHELKGEGKA |
700:
QRKISAIHIL | DVLVLNGSDV | REQHFNQRIQ | LAEKFVKAVS | KPSRPDMNPI |
750:
RVKEVYRLEE | MEKIFVRLEM | KLIKGSGGTP | KLSYTGRDDR | HFVPTGVYIV |
800:
RTVTEPWTMA | FSKGWKKKFF | YNKKTGESFF | TLPPESIAPF | HTCYYTRLFW |
837:
EWGDGFHMRD | SQKPQDPDKL | SKEDVLSFIQ | SHNPLGP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
Bovine
ELISA Kit for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
ELISA Kit for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
ELISA Kit for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
ELISA Kit for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
CLIA Kit for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
CLIA Kit for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
CLIA Kit for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
CLIA Kit for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Polyclonal Antibody for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Polyclonal Antibody for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Polyclonal Antibody for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Polyclonal Antibody for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Monoclonal Antibody for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Monoclonal Antibody for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Monoclonal Antibody for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Monoclonal Antibody for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Protein for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Protein for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Protein for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
Protein for Rat Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Brown Norway .
tissue :
Kidney .