Cmya5 ELISA Kit for Mouse(Mus musculus) | EIAab.comCmya5 ELISA Kit for Mouse(Mus musculus)

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Cmya5 (Gene name),

Cardiomyopathy-associated protein 5 (Protein name ), CMYA5_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cmya5(Sr553;Srfsd;Tims);

Protein name:

Cardiomyopathy-associated protein 5;

Alternative:

Myospryn;Heart and skeletal muscle-specific and sprouty domain-containing;Stretch-responsive fibronectin protein type 3;Stretch-response protein 553;TRIM-like protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with ACTN2, DES, DTNBP1/dysbindin and PRKAR2A.

Function:

N/A

Subcellular Location:

Cytoplasm Cytoplasm perinuclear region Found predominantly at the periphery of the nucleus but also throughout the cell. Localized at the Z-line costamere connection level of the sarcolemma and in lysosomes.

Protein Attributes:

Sequence length:

3739

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LFIVRHRFNE | GVHPAFALEK | PGRCTLHLGL | EPPDSVRHK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q70KF4

UniGene:

Mm.33857

Pfam:

PF00041

SMR:

Q70KF4

Uniprot:

Q70KF4

FOR

ELISA Kit for Mouse Cardiomyopathy-associated protein 5

CLIA Kit for Mouse Cardiomyopathy-associated protein 5

Polyclonal Antibody for Mouse Cardiomyopathy-associated protein 5

Monoclonal Antibody for Mouse Cardiomyopathy-associated protein 5

Protein for Mouse Cardiomyopathy-associated protein 5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Myospryn is a novel binding partner for dysbindin in muscle."
Benson M.A. , Tinsley C.L. , Blake D.J.
J. Biol. Chem.279:10450-10458(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH DTNBP1;TISSUE SPECIFICITY
strain: C57BL/6.
tissue: Skeletal muscle.
2.

"Characterisation of a novel stretch-sensitive gene encoding a Bbox/FN-3/SPRY domain containing protein."
McKoy G. , Kemp T. , Velineni R. , Shaw A.L. , Coulton G.R.
Submitted (2002-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/10.
tissue: Muscle.
3.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Tongue.
4.

"Identification and characterisation of novel skeletal muscle genes exhibiting increased expression in response to passive stretch."
Kemp T.J. , Sadusky T.J. , Coulton G.R.
Submitted (1999-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3534-3739;INDUCTION BY MECHANICAL STRETCH
strain: C57BL/10.
tissue: Skeletal muscle.
5.

"Myospryn is a direct transcriptional target for MEF2A that encodes a striated muscle, alpha-actinin-interacting, costamere-localized protein."
Durham J.T. , Brand O.M. , Arnold M. , Reynolds J.G. , Muthukumar L. , Weiler H. , Richardson J.A. , Naya F.J.
J. Biol. Chem.281:6841-6849(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ACTN2;DEVELOPMENTAL STAGE;TISSUE SPECIFICITY
6.

"Identification and mapping of protein kinase A binding sites in the costameric protein myospryn."
Reynolds J.G. , McCalmon S.A. , Tomczyk T. , Naya F.J.
Biochim. Biophys. Acta1773:891-902(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PRKAR2A;MUTAGENESIS OF LEU-3197; LEU-3309 AND CYS-3437;SUBCELLULAR LOCATION;PHOSPHORYLATION BY PKA
7.

"Proper perinuclear localization of the TRIM-like protein myospryn requires its binding partner desmin."
Kouloumenta A. , Mavroidis M. , Capetanaki Y.
J. Biol. Chem.282:35211-35221(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DES;SUBCELLULAR LOCATION
8.

"Deregulated protein kinase A signaling and myospryn expression in muscular dystrophy."
Reynolds J.G. , McCalmon S.A. , Donaghey J.A. , Naya F.J.
J. Biol. Chem.283:8070-8074(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH DMD;SUBCELLULAR LOCATION;INDUCTION;TISSUE SPECIFICITY
9.

"Interactions with M-band titin and calpain 3 link myospryn (CMYA5) to tibial and limb-girdle muscular dystrophies."
Sarparanta J. , Blandin G. , Charton K. , Vihola A. , Marchand S. , Milic A. , Hackman P. , Ehler E. , Richard I. , Udd B.
J. Biol. Chem.285:30304-30315(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
10.

"Myospryn is a calcineurin-interacting protein that negatively modulates slow-fiber-type transformation and skeletal muscle regeneration."
Kielbasa O.M. , Reynolds J.G. , Wu C.L. , Snyder C.M. , Cho M.Y. , Weiler H. , Kandarian S. , Naya F.J.
FASEB J.25:2276-2286(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PPP3CA

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